SULFAMETHOXAZOLE AND TRIMETHOPRIM

Sulfamethoxazole And Trimethoprim Adverse Events Reported to the FDA Over Time

How are Sulfamethoxazole And Trimethoprim adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Sulfamethoxazole And Trimethoprim, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Sulfamethoxazole And Trimethoprim is flagged as the suspect drug causing the adverse event.

Most Common Sulfamethoxazole And Trimethoprim Adverse Events Reported to the FDA

What are the most common Sulfamethoxazole And Trimethoprim adverse events reported to the FDA?

Pyrexia	250 (2.31%)
Renal Failure Acute	235 (2.17%)
Rash	179 (1.65%)
Nausea	139 (1.28%)
Hyperkalaemia	135 (1.25%)
Drug Interaction	107 (.99%)
Vomiting	103 (.95%)
Pruritus	93 (.86%)
Asthenia	88 (.81%)
Stevens-johnson Syndrome	88 (.81%)
Diarrhoea	86 (.79%)
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Blood Creatinine Increased	84 (.77%)
Hypotension	82 (.76%)
Thrombocytopenia	80 (.74%)
Urticaria	80 (.74%)
Drug Hypersensitivity	78 (.72%)
Dyspnoea	76 (.7%)
Headache	74 (.68%)
Chills	72 (.66%)
Neutropenia	72 (.66%)
Fatigue	70 (.65%)
Pancytopenia	67 (.62%)
Dizziness	66 (.61%)
Anaemia	64 (.59%)
Platelet Count Decreased	61 (.56%)
Dehydration	58 (.53%)
Hypersensitivity	58 (.53%)
Renal Impairment	57 (.53%)
Pain	56 (.52%)
Pneumocystis Jiroveci Pneumonia	56 (.52%)
Toxic Epidermal Necrolysis	55 (.51%)
Abdominal Pain	51 (.47%)
Sepsis	51 (.47%)
Erythema	50 (.46%)
Decreased Appetite	48 (.44%)
Pneumonia	48 (.44%)
Angioedema	47 (.43%)
Multi-organ Failure	46 (.42%)
Blood Urea Increased	45 (.42%)
Confusional State	45 (.42%)
Rash Generalised	45 (.42%)
Drug Ineffective	44 (.41%)
Drug Rash With Eosinophilia And Sys...	43 (.4%)
Malaise	41 (.38%)
Leukopenia	40 (.37%)
Respiratory Failure	39 (.36%)
Tremor	38 (.35%)
Urinary Tract Infection	38 (.35%)
Arthralgia	36 (.33%)
Condition Aggravated	36 (.33%)
Alanine Aminotransferase Increased	35 (.32%)
Rhabdomyolysis	35 (.32%)
Death	34 (.31%)
Hyponatraemia	34 (.31%)
Pain In Extremity	34 (.31%)
Tubulointerstitial Nephritis	34 (.31%)
Hepatitis	33 (.3%)
Rash Erythematous	33 (.3%)
Renal Failure	33 (.3%)
Skin Exfoliation	33 (.3%)
Aspartate Aminotransferase Increase...	32 (.3%)
Bone Marrow Failure	32 (.3%)
Cough	32 (.3%)
Metabolic Acidosis	32 (.3%)
Rash Maculo-papular	32 (.3%)
White Blood Cell Count Decreased	32 (.3%)
Convulsion	31 (.29%)
Hypertension	31 (.29%)
Hypoglycaemia	31 (.29%)
Lymphadenopathy	31 (.29%)
Myalgia	31 (.29%)
Oedema Peripheral	31 (.29%)
Septic Shock	31 (.29%)
Tachycardia	31 (.29%)
Abdominal Pain Upper	30 (.28%)
Chest Pain	30 (.28%)
Liver Disorder	30 (.28%)
Pleural Effusion	30 (.28%)
Cytomegalovirus Infection	29 (.27%)
Erythema Multiforme	29 (.27%)
Hepatic Function Abnormal	29 (.27%)
Interstitial Lung Disease	29 (.27%)
Jaundice	29 (.27%)
Cholestasis	28 (.26%)
Haemoglobin Decreased	28 (.26%)
Drug Eruption	27 (.25%)
Weight Decreased	27 (.25%)
Febrile Neutropenia	26 (.24%)
General Physical Health Deteriorati...	25 (.23%)
Insomnia	25 (.23%)
Rash Pruritic	25 (.23%)
Transplant Rejection	25 (.23%)
Anaphylactic Reaction	24 (.22%)
C-reactive Protein Increased	24 (.22%)
Completed Suicide	24 (.22%)
Gamma-glutamyltransferase Increased	24 (.22%)
Staphylococcal Infection	24 (.22%)
Blister	23 (.21%)
Blood Bilirubin Increased	23 (.21%)
Drug Toxicity	23 (.21%)
Aspergillosis	22 (.2%)

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This graph shows the top adverse events submitted to the FDA for Sulfamethoxazole And Trimethoprim, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Sulfamethoxazole And Trimethoprim is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Sulfamethoxazole And Trimethoprim

What are the most common Sulfamethoxazole And Trimethoprim adverse events reported to the FDA?

Epidermal And Dermal Conditions	1031 (9.51%)
Infections - Pathogen Unspecified	417 (3.85%)
Gastrointestinal Signs	402 (3.71%)
Renal Disorders	376 (3.47%)
Respiratory	325 (3%)
Hepatic And Hepatobiliary	321 (2.96%)
Neurological	284 (2.62%)
Electrolyte And Fluid Balance Condi...	263 (2.43%)
Body Temperature Conditions	256 (2.36%)
Hematology Investigations	251 (2.31%)
Therapeutic And Nontherapeutic Effe...	208 (1.92%)
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Anemias Nonhemolytic And Marrow Dep...	201 (1.85%)
White Blood Cell	199 (1.84%)
Bacterial Infectious	194 (1.79%)
Renal And Urinary Tract Investigati...	180 (1.66%)
Hepatobiliary	177 (1.63%)
Allergic Conditions	174 (1.6%)
Viral Infectious	168 (1.55%)
Fungal Infectious	162 (1.49%)
Cardiac Arrhythmias	132 (1.22%)
Angiedema And Urticaria	128 (1.18%)
Muscle	127 (1.17%)
Gastrointestinal Motility And Defec...	112 (1.03%)
Appetite And General Nutritional	101 (.93%)
Cardiac And Vascular Investigations	99 (.91%)
Decreased And Nonspecific Blood Pre...	97 (.89%)
Musculoskeletal And Connective Tiss...	93 (.86%)
Platelet	93 (.86%)
Lower Respiratory Tract Disorders	86 (.79%)
Movement Disorders	82 (.76%)
Headaches	79 (.73%)
Urinary Tract Signs	79 (.73%)
Oral Soft Tissue Conditions	77 (.71%)
Deliria	72 (.66%)
Nephropathies	68 (.63%)
Physical Examination Topics	64 (.59%)
Procedural And Device Related Injur...	62 (.57%)
Enzyme	61 (.56%)
Medication Errors	60 (.55%)
Chemical Injury And Poisoning	58 (.53%)
Immune	58 (.53%)
Glucose Metabolism Disorders	57 (.53%)
Water, Electrolyte And Mineral	57 (.53%)
Anxiety Disorders	52 (.48%)
Seizures	50 (.46%)
Joint	48 (.44%)
Skin Vascular Abnormalities	47 (.43%)
Ocular Infections, Irritations And ...	46 (.42%)
Acid-base	45 (.42%)
Upper Respiratory Tract Disorders	44 (.41%)
Microbiology And Serology	43 (.4%)
Injuries	41 (.38%)
Metabolic, Nutritional And Blood Ga...	41 (.38%)
Protein And Chemistry Analyses	41 (.38%)
Skin Appendage Conditions	41 (.38%)
Fatal Outcomes	39 (.36%)
Spleen, Lymphatic And Reticulendoth...	39 (.36%)
Exocrine Pancreas Conditions	38 (.35%)
Gastrointestinal Hemorrhages	37 (.34%)
Pleural	37 (.34%)
Suicidal And Self-injurious Behavio...	36 (.33%)
Sleep Disorders	35 (.32%)
Depressed Mood Disorders	34 (.31%)
Vision	34 (.31%)
Vascular Hypertensive	33 (.3%)
Central Nervous System Vascular	31 (.29%)
Vascular	31 (.29%)
Coagulopathies And Bleeding Diathes...	30 (.28%)
Peritoneal And Retroperitoneal Cond...	30 (.28%)
Psychiatric	30 (.28%)
Cardiac Disorder Signs	29 (.27%)
Encephalopathies	28 (.26%)
Disturbances In Thinking	27 (.25%)
Myocardial	27 (.25%)
Hematological And Lymphoid Tissue T...	26 (.24%)
Immunodeficiency Syndromes	26 (.24%)
Mental Impairment	26 (.24%)
Tissue	26 (.24%)
Lifestyle Issues	25 (.23%)
Tongue Conditions	24 (.22%)
Eye	23 (.21%)
Hemolyses And Related Conditions	23 (.21%)
Lipid Metabolism	23 (.21%)
Neurological, Special Senses And Ps...	22 (.2%)
Vascular Hemorrhagic	22 (.2%)
Mycobacterial Infectious	21 (.19%)
Toxicology And Therapeutic Drug Mon...	21 (.19%)
Bronchial Disorders	20 (.18%)
Gastrointestinal	20 (.18%)
Schizophrenia And Other Psychotic	20 (.18%)
Skin And Subcutaneous Tissue	20 (.18%)
Hematopoietic Neoplasms	19 (.18%)
Pulmonary Vascular	19 (.18%)
Gastrointestinal Inflammatory Condi...	18 (.17%)
Peripheral Neuropathies	18 (.17%)
Coronary Artery	17 (.16%)
Gastrointestinal Conditions	17 (.16%)
Heart Failures	17 (.16%)
Mood Disorders	17 (.16%)
Musculoskeletal And Connective Tiss...	17 (.16%)
Vascular Inflammations	17 (.16%)

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This graph shows the top categories of adverse events submitted to the FDA for Sulfamethoxazole And Trimethoprim, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Sulfamethoxazole And Trimethoprim is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.