The DrugCite Adverse Event Calculator is built on the Naranjo algorithm. This simple tool helps you identify the probability of an adverse event being associated with a drug. Simply answer the 10 questions below and the probability of an adverse event will be displayed at the bottom.
YES | NO | UNKOWN | |
---|---|---|---|
Are there previous conclusive reports on this reaction? | |||
Did the adverse event appear after the suspected drug was administered? | |||
Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered? | |||
Did the adverse reaction reappear when the drug was readministered? | |||
Are there alternative causes (other than the drug) that could on their own have caused the reaction? | |||
Did the reaction reappear when a placebo was given? | |||
Was the drug detected in the blood (or other fluids) in concentrations known to be toxic? | |||
Was the reaction more severe when the dose was increased, or less severe when the dose was decreased? | |||
Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | |||
Was the adverse event confirmed by any objective evidence? |