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ZYVOXID

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Zyvoxid Adverse Events Reported to the FDA Over Time

How are Zyvoxid adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Zyvoxid, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Zyvoxid is flagged as the suspect drug causing the adverse event.

Most Common Zyvoxid Adverse Events Reported to the FDA

What are the most common Zyvoxid adverse events reported to the FDA?

Anaemia
53 (4.8%)
Thrombocytopenia
52 (4.71%)
Renal Failure Acute
22 (1.99%)
Pancytopenia
18 (1.63%)
Pyrexia
15 (1.36%)
Confusional State
14 (1.27%)
Cytolytic Hepatitis
14 (1.27%)
Drug Interaction
14 (1.27%)
Hepatitis Acute
13 (1.18%)
Nausea
13 (1.18%)
Lactic Acidosis
12 (1.09%)
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Leukopenia
12 (1.09%)
Gamma-glutamyltransferase Increased
11 (1%)
Hepatitis Cholestatic
11 (1%)
Blood Bilirubin Increased
10 (.9%)
Jaundice
10 (.9%)
Hepatic Failure
9 (.81%)
Jaundice Cholestatic
9 (.81%)
Multi-organ Failure
9 (.81%)
Serotonin Syndrome
9 (.81%)
Abdominal Pain
8 (.72%)
Heparin-induced Thrombocytopenia
8 (.72%)
Rash
8 (.72%)
Transaminases Increased
8 (.72%)
C-reactive Protein Increased
7 (.63%)
Chills
7 (.63%)
Condition Aggravated
7 (.63%)
Drug Ineffective
7 (.63%)
Hallucination
7 (.63%)
Hypotension
7 (.63%)
Pain In Extremity
7 (.63%)
Pancreatitis
7 (.63%)
Vomiting
7 (.63%)
Arthralgia
6 (.54%)
Death
6 (.54%)
Myoclonus
6 (.54%)
Neuropathy Peripheral
6 (.54%)
Neutropenia
6 (.54%)
Polyarthritis
6 (.54%)
Renal Failure
6 (.54%)
Acute Generalised Exanthematous Pus...
5 (.45%)
Delirium
5 (.45%)
Drug Rash With Eosinophilia And Sys...
5 (.45%)
Dyspnoea
5 (.45%)
General Physical Health Deteriorati...
5 (.45%)
Hepatitis
5 (.45%)
Oedema Peripheral
5 (.45%)
Pathogen Resistance
5 (.45%)
Platelet Count Decreased
5 (.45%)
Polyneuropathy
5 (.45%)
Septic Shock
5 (.45%)
Shock
5 (.45%)
Acute Respiratory Distress Syndrome
4 (.36%)
Alanine Aminotransferase Increased
4 (.36%)
Aspartate Aminotransferase Increase...
4 (.36%)
Blood Alkaline Phosphatase Increase...
4 (.36%)
Cardiac Arrest
4 (.36%)
Cardiac Failure
4 (.36%)
Cholestasis
4 (.36%)
Encephalopathy
4 (.36%)
Eosinophilia
4 (.36%)
Haemodynamic Instability
4 (.36%)
Hepatic Encephalopathy
4 (.36%)
Hypoglycaemia
4 (.36%)
Hypokinesia
4 (.36%)
Mycotic Aneurysm
4 (.36%)
Paraesthesia
4 (.36%)
Pharyngeal Oedema
4 (.36%)
Staphylococcal Infection
4 (.36%)
Supraventricular Tachycardia
4 (.36%)
Toxic Encephalopathy
4 (.36%)
Tremor
4 (.36%)
Ventricular Extrasystoles
4 (.36%)
Acidosis
3 (.27%)
Agitation
3 (.27%)
Agranulocytosis
3 (.27%)
Anorexia
3 (.27%)
Asthenia
3 (.27%)
Blindness
3 (.27%)
Blood Urea Increased
3 (.27%)
Bone Marrow Failure
3 (.27%)
Cerebral Haemorrhage
3 (.27%)
Cholecystitis
3 (.27%)
Dehydration
3 (.27%)
Depressed Level Of Consciousness
3 (.27%)
Dermatitis
3 (.27%)
Dysaesthesia
3 (.27%)
Dyspnoea Exertional
3 (.27%)
Enterococcal Infection
3 (.27%)
Fatigue
3 (.27%)
Flatulence
3 (.27%)
Grand Mal Convulsion
3 (.27%)
Haematemesis
3 (.27%)
Haemoglobin Decreased
3 (.27%)
Haemoptysis
3 (.27%)
Haemorrhage
3 (.27%)
Hepatosplenomegaly
3 (.27%)
Hiccups
3 (.27%)
Hyperreflexia
3 (.27%)
Hypersensitivity
3 (.27%)
Hypertension
3 (.27%)

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This graph shows the top adverse events submitted to the FDA for Zyvoxid, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Zyvoxid is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Zyvoxid

What are the most common Zyvoxid adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Zyvoxid, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Zyvoxid is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Zyvoxid According to Those Reporting Adverse Events

Why are people taking Zyvoxid, according to those reporting adverse events to the FDA?

Staphylococcal Infection
45
Drug Use For Unknown Indication
24
Infection
19
Pneumonia Staphylococcal
11
Osteitis
10
Pneumonia
10
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Enterococcal Infection
9
Respiratory Tract Infection
8
Skin Infection
8
Lung Abscess
8
Endocarditis
8
Sepsis
8
Lung Disorder
7
Tuberculosis
6
Intervertebral Discitis
6
Septic Shock
6
Staphylococcal Sepsis
5
Device Related Infection
5
Arthritis Bacterial
5
Prophylaxis
4
Superinfection Lung
4
Infected Skin Ulcer
3
Abdominal Abscess
3
Klebsiella Infection
3
Abscess
3
Osteomyelitis
3
Bacterial Infection
3
Abnormal Faeces
2
Sinusitis
2
Erythema
2
Arthrodesis
2
Nocardiosis
2
Injury
2
Soft Tissue Infection
2
Urinary Tract Infection
2
Postoperative Wound Infection
2
Lung Infection
2
Peritonitis
2
Tracheobronchitis
2
Ill-defined Disorder
2
Pneumonia Legionella
1
Meningitis Tuberculous
1
Prostatitis
1
Cellulitis
1
Soft Tissue Necrosis
1
Respiratory Tract Infection Bacteri...
1
Meningitis
1
Bacteraemia
1
Escherichia Infection
1
Postoperative Infection
1
Streptococcal Infection
1

Zyvoxid Case Reports

What Zyvoxid safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Zyvoxid. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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