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VINDESINE

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Vindesine Adverse Events Reported to the FDA Over Time

How are Vindesine adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Vindesine, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Vindesine is flagged as the suspect drug causing the adverse event.

Most Common Vindesine Adverse Events Reported to the FDA

What are the most common Vindesine adverse events reported to the FDA?

Febrile Neutropenia
42 (2.78%)
Infection
37 (2.45%)
Thrombocytopenia
35 (2.32%)
Mucosal Inflammation
34 (2.25%)
Anaemia
33 (2.19%)
Febrile Bone Marrow Aplasia
27 (1.79%)
Pyrexia
26 (1.72%)
Sepsis
22 (1.46%)
Neutropenia
20 (1.32%)
Pancytopenia
20 (1.32%)
Acute Myeloid Leukaemia
19 (1.26%)
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Bone Marrow Failure
18 (1.19%)
Death
17 (1.13%)
Pneumocystis Jiroveci Pneumonia
17 (1.13%)
Pneumonia
15 (.99%)
Ileus Paralytic
14 (.93%)
Septic Shock
14 (.93%)
Diarrhoea
13 (.86%)
Acute Promyelocytic Leukaemia
12 (.79%)
Drug Toxicity
12 (.79%)
Dyspnoea
11 (.73%)
Interstitial Lung Disease
11 (.73%)
Oesophageal Candidiasis
11 (.73%)
Palmar-plantar Erythrodysaesthesia ...
11 (.73%)
Coagulopathy
10 (.66%)
Dysphagia
10 (.66%)
Haemoglobin Decreased
10 (.66%)
Leukopenia
10 (.66%)
Neurotoxicity
10 (.66%)
Renal Failure
10 (.66%)
Stomatitis
10 (.66%)
Venoocclusive Liver Disease
10 (.66%)
Alanine Aminotransferase Increased
9 (.6%)
Drug Ineffective
9 (.6%)
Hepatotoxicity
9 (.6%)
Hypoxia
9 (.6%)
Malignant Neoplasm Progression
9 (.6%)
Oral Candidiasis
9 (.6%)
Platelet Count Decreased
9 (.6%)
White Blood Cell Count Decreased
9 (.6%)
Aspartate Aminotransferase Increase...
8 (.53%)
Cardiac Failure
8 (.53%)
Escherichia Infection
8 (.53%)
Hiatus Hernia
8 (.53%)
Hyponatraemia
8 (.53%)
Lymphoma
8 (.53%)
Off Label Use
8 (.53%)
Pulmonary Fibrosis
8 (.53%)
Vomiting
8 (.53%)
Acute Respiratory Distress Syndrome
7 (.46%)
Aplasia
7 (.46%)
Asthenia
7 (.46%)
Blood Lactate Dehydrogenase Increas...
7 (.46%)
Cough
7 (.46%)
Deep Vein Thrombosis
7 (.46%)
Dialysis
7 (.46%)
Histiocytosis Haematophagic
7 (.46%)
Nausea
7 (.46%)
Oesophagitis
7 (.46%)
Renal Failure Acute
7 (.46%)
Tachycardia
7 (.46%)
Ascites
6 (.4%)
Cardiac Arrest
6 (.4%)
Chills
6 (.4%)
Clostridium Difficile Colitis
6 (.4%)
Cytomegalovirus Viraemia
6 (.4%)
Disease Progression
6 (.4%)
Enterocolitis
6 (.4%)
Haemorrhage
6 (.4%)
Headache
6 (.4%)
Lung Disorder
6 (.4%)
Nephropathy Toxic
6 (.4%)
Pneumocystis Jiroveci Infection
6 (.4%)
Pneumonitis
6 (.4%)
Blood Culture Positive
5 (.33%)
Caecitis
5 (.33%)
Gamma-glutamyltransferase Increased
5 (.33%)
Gastroenteritis
5 (.33%)
General Physical Health Deteriorati...
5 (.33%)
Haematotoxicity
5 (.33%)
Hepatic Failure
5 (.33%)
Hypertriglyceridaemia
5 (.33%)
Hypovolaemic Shock
5 (.33%)
Lymphopenia
5 (.33%)
Multi-organ Failure
5 (.33%)
Neutropenic Infection
5 (.33%)
Pleural Effusion
5 (.33%)
Pseudomonal Sepsis
5 (.33%)
Pseudomonas Infection
5 (.33%)
Rectal Haemorrhage
5 (.33%)
Staphylococcal Infection
5 (.33%)
Sudden Death
5 (.33%)
Treatment Failure
5 (.33%)
Treatment Related Secondary Maligna...
5 (.33%)
Weight Decreased
5 (.33%)
Abdominal Pain
4 (.26%)
Acute Lymphocytic Leukaemia Recurre...
4 (.26%)
Aspergillosis
4 (.26%)
Blast Cell Crisis
4 (.26%)
Blood Creatinine Increased
4 (.26%)
Cardiac Disorder
4 (.26%)

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This graph shows the top adverse events submitted to the FDA for Vindesine, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vindesine is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Vindesine

What are the most common Vindesine adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Vindesine, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vindesine is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Vindesine According to Those Reporting Adverse Events

Why are people taking Vindesine, according to those reporting adverse events to the FDA?

T-cell Lymphoma
76
Non-hodgkins Lymphoma
53
Diffuse Large B-cell Lymphoma
49
Acute Lymphocytic Leukaemia
36
Lymphoma
32
B-cell Lymphoma
28
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Product Used For Unknown Indication
26
Peripheral T-cell Lymphoma Unspecif...
22
Burkitts Lymphoma
17
Adult T-cell Lymphoma/leukaemia
15
Hodgkins Disease
12
Chemotherapy
11
Drug Use For Unknown Indication
11
Leukaemia
7
Anaplastic Large Cell Lymphoma T- A...
4
Lung Neoplasm Malignant
4
Multiple Myeloma
4
Acute Lymphocytic Leukaemia Recurre...
3
B Precursor Type Acute Leukaemia
3
Chronic Myeloid Leukaemia
3
Langerhans Cell Granulomatosis
3
Ill-defined Disorder
3
Lymphoproliferative Disorder
2
Diffuse Large B-cell Lymphoma Stage...
2
Neoplasm Malignant
2
Uterine Leiomyosarcoma
2
Acute Promyelocytic Leukaemia
2
Peripheral T-cell Lymphoma Unspecif...
2
Lung Squamous Cell Carcinoma Stage ...
2
T-cell Lymphoma Stage Iv
2
Haematological Malignancy
2
Central Nervous System Lymphoma
2
Malignant Melanoma
2
Acute Myeloid Leukaemia
2
Non-hodgkins Lymphoma Metastatic
2
Lung Squamous Cell Carcinoma Stage ...
1
Lung Adenocarcinoma Stage Iv
1
Precursor T-lymphoblastic Lymphoma/...
1
Precursor B-lymphoblastic Lymphoma
1
Breast Cancer
1
Immunoblastic Lymphoma
1
Small Cell Lung Cancer Stage Unspec...
1
Malignant Respiratory Tract Neoplas...
1
Hodgkins Disease Stage Iii
1

Vindesine Case Reports

What Vindesine safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Vindesine. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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