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Verapamil Adverse Events Reported to the FDA Over Time

How are Verapamil adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Verapamil, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Verapamil is flagged as the suspect drug causing the adverse event.

Most Common Verapamil Adverse Events Reported to the FDA

What are the most common Verapamil adverse events reported to the FDA?

Completed Suicide
1048 (4.65%)
Hypotension
581 (2.58%)
Bradycardia
520 (2.31%)
Drug Interaction
398 (1.76%)
Overdose
303 (1.34%)
Dizziness
297 (1.32%)
Drug Ineffective
250 (1.11%)
Dyspnoea
244 (1.08%)
Drug Toxicity
233 (1.03%)
Nausea
230 (1.02%)
Death
229 (1.02%)
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Cardiac Arrest
221 (.98%)
Vomiting
200 (.89%)
Atrial Fibrillation
197 (.87%)
Metabolic Acidosis
196 (.87%)
Asthenia
195 (.86%)
Suicide Attempt
190 (.84%)
Intentional Overdose
176 (.78%)
Hyperkalaemia
166 (.74%)
Renal Failure
163 (.72%)
Renal Failure Acute
163 (.72%)
Headache
158 (.7%)
Cardiogenic Shock
152 (.67%)
Malaise
143 (.63%)
Syncope
142 (.63%)
Loss Of Consciousness
138 (.61%)
Atrioventricular Block Complete
136 (.6%)
Blood Pressure Increased
136 (.6%)
Somnolence
135 (.6%)
Shock
134 (.59%)
Fatigue
128 (.57%)
Hypertension
126 (.56%)
Blood Pressure Decreased
121 (.54%)
Chest Pain
115 (.51%)
Atrioventricular Block
108 (.48%)
Medication Error
106 (.47%)
Pulmonary Oedema
102 (.45%)
Cardiac Failure
100 (.44%)
Palpitations
99 (.44%)
Abdominal Pain
98 (.43%)
Cough
96 (.43%)
Heart Rate Decreased
95 (.42%)
Constipation
92 (.41%)
Hallucination
90 (.4%)
Hyperhidrosis
90 (.4%)
Poisoning
90 (.4%)
Depressed Level Of Consciousness
89 (.39%)
Blood Creatinine Increased
87 (.39%)
Diarrhoea
87 (.39%)
Cardio-respiratory Arrest
86 (.38%)
Confusional State
86 (.38%)
Pyrexia
84 (.37%)
Respiratory Arrest
84 (.37%)
Nodal Rhythm
82 (.36%)
Anuria
81 (.36%)
Dehydration
79 (.35%)
Hyperglycaemia
77 (.34%)
Oedema Peripheral
76 (.34%)
Multiple Drug Overdose
75 (.33%)
Atrioventricular Block First Degree
73 (.32%)
Cardiomegaly
71 (.31%)
Rhabdomyolysis
71 (.31%)
Coma
69 (.31%)
Feeling Abnormal
69 (.31%)
Multiple Drug Overdose Intentional
69 (.31%)
Hypokalaemia
68 (.3%)
Anxiety
67 (.3%)
Fall
67 (.3%)
Circulatory Collapse
66 (.29%)
Condition Aggravated
65 (.29%)
Pruritus
65 (.29%)
Pulse Absent
65 (.29%)
Depression
64 (.28%)
Multi-organ Failure
63 (.28%)
Orthostatic Hypotension
61 (.27%)
Arrhythmia
60 (.27%)
Blood Creatine Phosphokinase Increa...
60 (.27%)
Heart Rate Increased
60 (.27%)
Hypoxia
60 (.27%)
Blood Glucose Increased
59 (.26%)
Haemodialysis
58 (.26%)
Oedema
58 (.26%)
Sinus Bradycardia
58 (.26%)
Decreased Appetite
56 (.25%)
Abdominal Discomfort
55 (.24%)
Arthralgia
55 (.24%)
Toxic Epidermal Necrolysis
55 (.24%)
Atrioventricular Block Second Degre...
54 (.24%)
Hepatitis
54 (.24%)
Intentional Drug Misuse
53 (.24%)
Blood Pressure Inadequately Control...
52 (.23%)
Presyncope
52 (.23%)
Tachycardia
52 (.23%)
Acute Respiratory Distress Syndrome
50 (.22%)
General Physical Health Deteriorati...
50 (.22%)
Alanine Aminotransferase Increased
49 (.22%)
Off Label Use
49 (.22%)
Hypersensitivity
48 (.21%)
Renal Impairment
48 (.21%)
Hypoglycaemia
47 (.21%)
Myocardial Infarction
47 (.21%)

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This graph shows the top adverse events submitted to the FDA for Verapamil, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Verapamil is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Verapamil

What are the most common Verapamil adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Verapamil, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Verapamil is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Verapamil According to Those Reporting Adverse Events

Why are people taking Verapamil, according to those reporting adverse events to the FDA?

Hypertension
2893
Drug Use For Unknown Indication
1313
Product Used For Unknown Indication
927
Atrial Fibrillation
566
Blood Pressure
240
Arrhythmia
197
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Migraine
172
Cardiac Disorder
148
Tachycardia
142
Supraventricular Tachycardia
141
Ill-defined Disorder
99
Essential Hypertension
93
Blood Pressure Increased
81
Suicide Attempt
76
Angina Pectoris
74
Cluster Headache
61
Heart Rate Irregular
59
Palpitations
58
Blood Pressure Abnormal
57
Atrial Flutter
40
Heart Rate Increased
33
Tachycardia Paroxysmal
32
Migraine Prophylaxis
31
Tachyarrhythmia
30
Headache
29
Hypertrophic Cardiomyopathy
28
Intentional Overdose
27
Mitral Valve Prolapse
26
Coronary Artery Disease
26
Myocardial Ischaemia
25
Atrial Tachycardia
23
Cardiac Failure
22
Prophylaxis
22
Depression
19
Cardiomyopathy
19
Overdose
17
Sinus Tachycardia
14
Heart Rate
13
Arteriospasm Coronary
13
Ventricular Tachycardia
12
Supraventricular Extrasystoles
11
Chest Pain
11
Heart Rate Abnormal
11
Ventricular Extrasystoles
11
Completed Suicide
11
Cardiovascular Disorder
10
Myocardial Infarction
10
Vasospasm
10
Cardiac Fibrillation
9
Ischaemic Cardiomyopathy
9
Acute Myocardial Infarction
9

Drug Labels

LabelLabelerEffective
Verapamil HydrochlorideBryant Ranch Prepack01-OCT-86
Verapamil HydrochloridePD-Rx Pharmaceuticals, Inc.28-AUG-06
Verapamil HydrochlorideBryant Ranch Prepack20-APR-10
Verapamil HydrochlorideState of Florida DOH Central Pharmacy03-JUN-10
Verapamil HydrochlorideState of Florida DOH Central Pharmacy19-AUG-10
Verapamil HydrochlorideBlenheim Pharmacal, Inc.20-AUG-10
Verapamil HydrochlorideMylan Pharmaceuticals Inc.26-AUG-10
Calan SrG.D. Searle LLC Division of Pfizer Inc02-SEP-10
Verapamil HydrochlorideREMEDYREPACK INC. 22-NOV-10
Verapamil HydrochlorideRebel Distributors Corp01-DEC-10
Verapamil HydrochlorideRebel Distributors Corp04-JAN-11
Trandolapril And Verapamil HydrochlorideGlenmark Generics Inc., USA17-JAN-11
Verapamil HydrochloridePreferred Pharmaceuticals, Inc.27-JAN-11
Verapamil HydrochloridePD-Rx Pharmaceuticals, Inc.27-JAN-11
Verapamil HydrochlorideMylan Institutional Inc.04-MAR-11
Verapamil HydrochlorideMylan Institutional Inc.08-APR-11
Verapamil HydrochlorideREMEDYREPACK INC. 25-JUL-11
Verapamil HydrochlorideREMEDYREPACK INC. 08-AUG-11
VerapamilPD-Rx Pharmaceuticals, Inc.11-AUG-11
Verapamil HydrochlorideREMEDYREPACK INC. 24-AUG-11
Verapamil HydrochlorideKremers Urban Pharmaceuticals Inc.01-SEP-11
Verelan PmUCB, Inc.01-SEP-11
Verapamil HydrochlorideHospira, Inc.03-OCT-11
CalanG.D. Searle LLC Division of Pfizer Inc18-OCT-11
Covera-hsG.D. Searle LLC Division of Pfizer Inc18-OCT-11
Verapamil HydrochlorideREMEDYREPACK INC. 16-NOV-11
VerelanUCB, Inc.01-DEC-11
Verapamil HydrochlorideREMEDYREPACK INC. 07-DEC-11
Verapamil HydrochlorideREMEDYREPACK INC. 13-DEC-11
Verapamil HydrochlorideCaraco Pharmaceutical Laboratories, Ltd.03-JAN-12
TarkaPhysicians Total Care, Inc.13-FEB-12
Verapamil HydrochlorideCardinal Health03-APR-12
VerapamilApotex Corp.12-APR-12
Verapamil HydrochlorideHeritage Pharmaceuticals Inc.19-APR-12
Verapamil HydrochlorideNCS HealthCare of KY, Inc dba Vangard Labs23-APR-12
Verapamil HydrochlorideHeritage Pharmaceuticals Inc.26-APR-12
Verapamil HydrochlorideGeneral Injectables & Vaccines, Inc08-JUN-12
Verapamil Hydrochloride General Injectables & Vaccines, Inc12-JUN-12
Verapamil HydrochlorideWatson Laboratories, Inc.14-JUN-12
Verapamil HydrochlorideNCS HealthCare of KY, Inc dba Vangard Labs18-JUN-12
Verapamil HydrochlorideGlenmark Generics Inc.,USA21-JUN-12
Verapamil HydrochloridePhysicians Total Care, Inc.27-JUN-12
Verapamil HydrochloridePhysicians Total Care, Inc.27-JUN-12
Verapamil HydrochloridePhysicians Total Care, Inc.27-JUN-12
Verapamil HydrochlorideMylan Pharmaceuticals Inc.30-JUN-12
Verapamil HydrochloridePreferred Pharmaceuticals, Inc.24-JUL-12
Verapamil HydrochlorideIVAX Pharmaceuticals, Inc.03-AUG-12
Verapamil HydrochlorideMajor Pharmaceuticals06-AUG-12
Verapamil HydrochlorideCardinal Health09-AUG-12
Verapamil HydrochloridePhysicians Total Care, Inc.18-SEP-12
TarkaAbbott Laboratories25-SEP-12
Verapamil HydrochlorideREMEDYREPACK INC. 02-OCT-12
Verapamil HydrochlorideWatson Laboratories, Inc.07-DEC-12
Verapamil HydrochlorideBryant Ranch Prepack17-JAN-13
Verelan PmBryant Ranch Prepack17-JAN-13
Verapamil HydrochlorideBryant Ranch Prepack18-JAN-13
Verapamil HydrochlorideBryant Ranch Prepack18-JAN-13
Verapamil HydrochlorideMylan Pharmaceuticals Inc.22-JAN-13
Verapamil HydrochloridepmMylan Pharmaceuticals Inc.13-FEB-13
Verapamil HydrochlorideREMEDYREPACK INC. 14-MAR-13
Verapamil HydrochlorideCardinal Health30-APR-13

Verapamil Case Reports

What Verapamil safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Verapamil. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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