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Vepesid Adverse Events Reported to the FDA Over Time

How are Vepesid adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Vepesid, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Vepesid is flagged as the suspect drug causing the adverse event.

Most Common Vepesid Adverse Events Reported to the FDA

What are the most common Vepesid adverse events reported to the FDA?

Interstitial Lung Disease
45 (2.37%)
Neutropenia
43 (2.26%)
White Blood Cell Count Decreased
34 (1.79%)
Malignant Neoplasm Progression
30 (1.58%)
Pyrexia
30 (1.58%)
Sepsis
29 (1.53%)
Anaemia
28 (1.47%)
Acute Myeloid Leukaemia
26 (1.37%)
Bone Marrow Failure
25 (1.32%)
Vomiting
24 (1.26%)
Pneumonia
22 (1.16%)
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Death
21 (1.11%)
Thrombocytopenia
21 (1.11%)
Febrile Neutropenia
20 (1.05%)
Nausea
20 (1.05%)
Pancytopenia
20 (1.05%)
Cardiac Failure
19 (1%)
Disseminated Intravascular Coagulat...
19 (1%)
Septic Shock
18 (.95%)
Dyspnoea
17 (.9%)
Leukopenia
17 (.9%)
Platelet Count Decreased
17 (.9%)
Renal Failure
17 (.9%)
Treatment Related Secondary Maligna...
17 (.9%)
Diarrhoea
16 (.84%)
Myelodysplastic Syndrome
16 (.84%)
Pneumonitis
16 (.84%)
C-reactive Protein Increased
14 (.74%)
Deep Vein Thrombosis
14 (.74%)
Renal Impairment
14 (.74%)
Stomatitis
14 (.74%)
Blood Pressure Decreased
13 (.68%)
Alanine Aminotransferase Increased
12 (.63%)
Aspartate Aminotransferase Increase...
12 (.63%)
Encephalopathy
12 (.63%)
Pulmonary Embolism
12 (.63%)
Acute Respiratory Distress Syndrome
11 (.58%)
Febrile Bone Marrow Aplasia
11 (.58%)
Renal Failure Acute
11 (.58%)
Respiratory Failure
11 (.58%)
Diplopia
10 (.53%)
Disorientation
10 (.53%)
Infection
10 (.53%)
Leukodystrophy
10 (.53%)
Multi-organ Failure
10 (.53%)
Pleural Effusion
10 (.53%)
Pupils Unequal
10 (.53%)
Tremor
10 (.53%)
Convulsion
9 (.47%)
Blood Creatinine Increased
8 (.42%)
Confusional State
8 (.42%)
Dysarthria
8 (.42%)
Histiocytosis Haematophagic
8 (.42%)
Hypokalaemia
8 (.42%)
Memory Impairment
8 (.42%)
Neoplasm Recurrence
8 (.42%)
Nervous System Disorder
8 (.42%)
Neutrophil Count Decreased
8 (.42%)
Dehydration
7 (.37%)
Drug Ineffective
7 (.37%)
Haemoglobin Decreased
7 (.37%)
Hyperthermia
7 (.37%)
Liver Disorder
7 (.37%)
Pneumonia Bacterial
7 (.37%)
Respiratory Distress
7 (.37%)
Subdural Haematoma
7 (.37%)
Venoocclusive Liver Disease
7 (.37%)
Agranulocytosis
6 (.32%)
Blood Lactate Dehydrogenase Increas...
6 (.32%)
Cytomegalovirus Infection
6 (.32%)
Gastrointestinal Haemorrhage
6 (.32%)
General Physical Health Deteriorati...
6 (.32%)
Hypersensitivity
6 (.32%)
Leukaemia
6 (.32%)
Lung Disorder
6 (.32%)
Mucosal Inflammation
6 (.32%)
Neoplasm Progression
6 (.32%)
Oxygen Saturation Decreased
6 (.32%)
Pregnancy
6 (.32%)
Rash
6 (.32%)
Thrombotic Microangiopathy
6 (.32%)
Tumour Lysis Syndrome
6 (.32%)
Abdominal Pain
5 (.26%)
Alopecia
5 (.26%)
Asthenia
5 (.26%)
Blood Urea Increased
5 (.26%)
Cough
5 (.26%)
Fatigue
5 (.26%)
Hemiparesis
5 (.26%)
Hepatic Failure
5 (.26%)
Hypertension
5 (.26%)
Hyponatraemia
5 (.26%)
Hypotension
5 (.26%)
Loss Of Consciousness
5 (.26%)
Lymphoma
5 (.26%)
Pneumothorax
5 (.26%)
Pseudomembranous Colitis
5 (.26%)
Renal Disorder
5 (.26%)
Shock
5 (.26%)
Arrhythmia
4 (.21%)
Aspergillosis
4 (.21%)

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This graph shows the top adverse events submitted to the FDA for Vepesid, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vepesid is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Vepesid

What are the most common Vepesid adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Vepesid, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vepesid is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Vepesid According to Those Reporting Adverse Events

Why are people taking Vepesid, according to those reporting adverse events to the FDA?

Small Cell Lung Cancer Stage Unspec...
63
Stem Cell Transplant
61
Non-hodgkins Lymphoma
53
Lymphoma
44
Lung Neoplasm Malignant
31
Testis Cancer
30
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Acute Lymphocytic Leukaemia
27
Hodgkins Disease
18
Bone Sarcoma
14
Acute Myeloid Leukaemia
14
Adult T-cell Lymphoma/leukaemia
14
Ovarian Cancer
12
Neoplasm Malignant
11
Histiocytosis Haematophagic
11
Diffuse Large B-cell Lymphoma
11
Drug Use For Unknown Indication
11
Prostate Cancer
11
Neuroblastoma
11
B-cell Lymphoma
11
Cervix Carcinoma
11
Bronchial Carcinoma
7
Lung Cancer Metastatic
7
Ewings Sarcoma
6
Nongerminomatous Germ Cell Tumour O...
6
Choriocarcinoma
5
Ovarian Germ Cell Cancer
5
Hepatoblastoma
5
Bone Marrow Transplant
5
Retinoblastoma Bilateral
5
Burkitts Lymphoma
5
Malignant Mediastinal Neoplasm
5
Adrenocortical Carcinoma
5
Germ Cell Cancer
5
Malignant Soft Tissue Neoplasm
5
Testicular Germ Cell Cancer
4
Gastric Cancer
4
Cord Blood Transplant Therapy
4
Rhabdomyosarcoma
4
Malignant Fibrous Histiocytoma
4
Medulloblastoma
3
Allogenic Bone Marrow Transplantati...
3
Leukaemia
3
Bone Marrow Conditioning Regimen
3
Synovial Sarcoma
3
Alveolar Soft Part Sarcoma
3
Multiple Myeloma
3
Glioblastoma Multiforme
3
Seminoma
3
Chronic Myelomonocytic Leukaemia
3
Lymphoproliferative Disorder
3
Brain Neoplasm
3

Vepesid Case Reports

What Vepesid safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Vepesid. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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