VANCOMYCIN

Vancomycin Adverse Events Reported to the FDA Over Time

How are Vancomycin adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Vancomycin, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Vancomycin is flagged as the suspect drug causing the adverse event.

Most Common Vancomycin Adverse Events Reported to the FDA

What are the most common Vancomycin adverse events reported to the FDA?

Renal Failure Acute	665 (2.72%)
Pyrexia	532 (2.17%)
Drug Rash With Eosinophilia And Sys...	400 (1.63%)
Rash	386 (1.58%)
Renal Failure	274 (1.12%)
Pruritus	266 (1.09%)
Toxic Epidermal Necrolysis	264 (1.08%)
Thrombocytopenia	242 (.99%)
Blood Creatinine Increased	235 (.96%)
Hypotension	217 (.89%)
Sepsis	199 (.81%)
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Stevens-johnson Syndrome	197 (.8%)
Erythema	176 (.72%)
Neutropenia	176 (.72%)
Diarrhoea	170 (.69%)
Dyspnoea	168 (.69%)
Renal Impairment	168 (.69%)
Septic Shock	165 (.67%)
Drug Hypersensitivity	159 (.65%)
Eosinophilia	159 (.65%)
Rash Erythematous	153 (.62%)
Anaemia	148 (.6%)
Pneumonia	145 (.59%)
Red Man Syndrome	142 (.58%)
Tachycardia	131 (.54%)
Multi-organ Failure	124 (.51%)
Staphylococcal Infection	123 (.5%)
Alanine Aminotransferase Increased	122 (.5%)
Aspartate Aminotransferase Increase...	121 (.49%)
Platelet Count Decreased	121 (.49%)
Rash Generalised	121 (.49%)
Rash Maculo-papular	119 (.49%)
Nausea	118 (.48%)
Chills	117 (.48%)
Dermatitis Exfoliative	117 (.48%)
Leukopenia	117 (.48%)
Infusion Related Reaction	116 (.47%)
Respiratory Failure	115 (.47%)
Nephropathy Toxic	114 (.47%)
White Blood Cell Count Decreased	114 (.47%)
Drug Ineffective	111 (.45%)
Vomiting	110 (.45%)
Pancytopenia	109 (.45%)
Condition Aggravated	105 (.43%)
Toxic Skin Eruption	105 (.43%)
Haemodialysis	101 (.41%)
General Physical Health Deteriorati...	100 (.41%)
Urticaria	99 (.4%)
Hepatic Function Abnormal	97 (.4%)
Drug Interaction	95 (.39%)
Drug Level Increased	95 (.39%)
Hypersensitivity	95 (.39%)
Oedema Peripheral	94 (.38%)
Tubulointerstitial Nephritis	90 (.37%)
Liver Disorder	88 (.36%)
Skin Exfoliation	87 (.36%)
Dialysis	85 (.35%)
Disseminated Intravascular Coagulat...	85 (.35%)
Renal Tubular Necrosis	85 (.35%)
Haemoglobin Decreased	84 (.34%)
Headache	81 (.33%)
Confusional State	78 (.32%)
Metabolic Acidosis	78 (.32%)
Agranulocytosis	76 (.31%)
Linear Iga Disease	76 (.31%)
Purpura	74 (.3%)
Drug Eruption	73 (.3%)
Hypokalaemia	73 (.3%)
Rash Pruritic	73 (.3%)
Anaphylactic Reaction	71 (.29%)
Face Oedema	71 (.29%)
Infection	71 (.29%)
Lymphadenopathy	71 (.29%)
Pleural Effusion	71 (.29%)
Acute Respiratory Distress Syndrome	70 (.29%)
Cytolytic Hepatitis	70 (.29%)
Dehydration	70 (.29%)
Cardiac Arrest	69 (.28%)
Respiratory Distress	69 (.28%)
Hypoxia	68 (.28%)
Blister	67 (.27%)
Febrile Neutropenia	67 (.27%)
Acute Generalised Exanthematous Pus...	66 (.27%)
Asthenia	66 (.27%)
Death	63 (.26%)
Hypertension	63 (.26%)
Blood Alkaline Phosphatase Increase...	62 (.25%)
Pain	61 (.25%)
Dizziness	59 (.24%)
Flushing	59 (.24%)
Gamma-glutamyltransferase Increased	59 (.24%)
Haemorrhage	58 (.24%)
Dermatitis Bullous	57 (.23%)
Deafness	56 (.23%)
Blood Urea Increased	54 (.22%)
Cholestasis	54 (.22%)
Cellulitis	53 (.22%)
Convulsion	53 (.22%)
Inflammation	52 (.21%)
Cardio-respiratory Arrest	51 (.21%)
Disorientation	51 (.21%)

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This graph shows the top adverse events submitted to the FDA for Vancomycin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vancomycin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Vancomycin

What are the most common Vancomycin adverse events reported to the FDA?

Epidermal And Dermal Conditions	3432 (14.02%)
Renal Disorders	1352 (5.52%)
Infections - Pathogen Unspecified	1230 (5.02%)
Bacterial Infectious	759 (3.1%)
Respiratory	718 (2.93%)
White Blood Cell	676 (2.76%)
Hematology Investigations	670 (2.74%)
Neurological	601 (2.45%)
Hepatic And Hepatobiliary	571 (2.33%)
Body Temperature Conditions	558 (2.28%)
Hepatobiliary	445 (1.82%)
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Cardiac Arrhythmias	440 (1.8%)
Renal And Urinary Tract Investigati...	402 (1.64%)
Therapeutic And Nontherapeutic Effe...	383 (1.56%)
Gastrointestinal Signs	372 (1.52%)
Allergic Conditions	371 (1.52%)
Anemias Nonhemolytic And Marrow Dep...	366 (1.49%)
Electrolyte And Fluid Balance Condi...	301 (1.23%)
Decreased And Nonspecific Blood Pre...	292 (1.19%)
Platelet	274 (1.12%)
Nephropathies	273 (1.12%)
Fungal Infectious	266 (1.09%)
Lower Respiratory Tract Disorders	260 (1.06%)
Gastrointestinal Motility And Defec...	219 (.89%)
Administration Site Reactions	215 (.88%)
Hematological And Lymphoid Tissue T...	212 (.87%)
Cardiac And Vascular Investigations	174 (.71%)
Skin Vascular Abnormalities	170 (.69%)
Medication Errors	169 (.69%)
Procedural And Device Related Injur...	155 (.63%)
Deliria	153 (.62%)
Central Nervous System Vascular	151 (.62%)
Joint	151 (.62%)
Viral Infectious	149 (.61%)
Toxicology And Therapeutic Drug Mon...	145 (.59%)
Injuries	143 (.58%)
Oral Soft Tissue Conditions	142 (.58%)
Musculoskeletal And Connective Tiss...	135 (.55%)
Angiedema And Urticaria	132 (.54%)
Hearing	128 (.52%)
Coagulopathies And Bleeding Diathes...	127 (.52%)
Physical Examination Topics	126 (.51%)
Enzyme	123 (.5%)
Movement Disorders	122 (.5%)
Microbiology And Serology	115 (.47%)
Muscle	114 (.47%)
Vascular	114 (.47%)
Spleen, Lymphatic And Reticulendoth...	111 (.45%)
Gastrointestinal Hemorrhages	106 (.43%)
Seizures	106 (.43%)
Acid-base	95 (.39%)
Pleural	95 (.39%)
Heart Failures	90 (.37%)
Encephalopathies	89 (.36%)
Headaches	87 (.36%)
Water, Electrolyte And Mineral	81 (.33%)
Urinary Tract Signs	80 (.33%)
Coronary Artery	79 (.32%)
Metabolic, Nutritional And Blood Ga...	79 (.32%)
Ocular Infections, Irritations And ...	77 (.31%)
Skin Appendage Conditions	77 (.31%)
Chemical Injury And Poisoning	75 (.31%)
Glucose Metabolism Disorders	74 (.3%)
Protein And Chemistry Analyses	74 (.3%)
Fatal Outcomes	72 (.29%)
Anxiety Disorders	69 (.28%)
Vascular Hemorrhagic	68 (.28%)
Gastrointestinal Inflammatory Condi...	67 (.27%)
Upper Respiratory Tract Disorders	67 (.27%)
Bronchial Disorders	65 (.27%)
Lifestyle Issues	63 (.26%)
Vascular Hypertensive	63 (.26%)
Gastrointestinal Ulceration And Per...	62 (.25%)
Appetite And General Nutritional	59 (.24%)
Cardiac Valve	55 (.22%)
Inner Ear And Viiith Cranial Nerve	55 (.22%)
Psychiatric	55 (.22%)
Immune	50 (.2%)
Ocular Neuromuscular	50 (.2%)
Peripheral Neuropathies	50 (.2%)
Vision	50 (.2%)
Neonatal And Perinatal Conditions	49 (.2%)
Peritoneal And Retroperitoneal Cond...	47 (.19%)
Therapeutic Procedures And Supporti...	46 (.19%)
Cardiac Disorder Signs	45 (.18%)
Skin And Subcutaneous Tissue	45 (.18%)
Bone And Joint Injuries	43 (.18%)
Bone And Joint Therapeutic Procedur...	43 (.18%)
Bone, Calcium, Magnesium And Phosph...	42 (.17%)
Disturbances In Thinking	42 (.17%)
Immunology And Allergy	41 (.17%)
Depressed Mood Disorders	39 (.16%)
Gastrointestinal Therapeutic Proced...	39 (.16%)
Hemolyses And Related Conditions	39 (.16%)
Bone Disorders	38 (.16%)
Eye	37 (.15%)
Tongue Conditions	37 (.15%)
Tissue	36 (.15%)
Embolism And Thrombosis	35 (.14%)
Protein And Amino Acid Metabolism	35 (.14%)
Vascular Inflammations	35 (.14%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Vancomycin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vancomycin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.