DrugCite
Search

PERINDOPRIL

Adverse Events
Drug Profile
Learn More
Reference
About Results
Comments

Perindopril Adverse Events Reported to the FDA Over Time

How are Perindopril adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Perindopril, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Perindopril is flagged as the suspect drug causing the adverse event.

Most Common Perindopril Adverse Events Reported to the FDA

What are the most common Perindopril adverse events reported to the FDA?

Renal Failure Acute
373 (2.59%)
Hypotension
213 (1.48%)
Renal Failure
206 (1.43%)
Hyperkalaemia
201 (1.4%)
Fall
197 (1.37%)
Dyspnoea
194 (1.35%)
Dizziness
188 (1.31%)
Drug Interaction
188 (1.31%)
Cardiac Murmur
162 (1.13%)
Atrial Fibrillation
156 (1.08%)
Malaise
144 (1%)
Show More Show More
Fatigue
141 (.98%)
Pyrexia
135 (.94%)
Paraesthesia
133 (.92%)
Oedema Peripheral
118 (.82%)
Hyponatraemia
108 (.75%)
Cough
107 (.74%)
Dehydration
103 (.72%)
Drug Ineffective
103 (.72%)
Hypertension
100 (.7%)
Metabolic Acidosis
100 (.7%)
Loss Of Consciousness
94 (.65%)
Ventricular Tachycardia
93 (.65%)
Feeling Abnormal
92 (.64%)
Urinary Tract Infection
92 (.64%)
Diarrhoea
83 (.58%)
Venous Pressure Jugular Increased
83 (.58%)
Nausea
81 (.56%)
Angioedema
80 (.56%)
Bradycardia
78 (.54%)
Left Ventricular Dysfunction
78 (.54%)
Sinus Tachycardia
78 (.54%)
White Blood Cell Count Increased
78 (.54%)
Blood Creatinine Increased
75 (.52%)
Rash
75 (.52%)
Thrombocytopenia
73 (.51%)
Constipation
72 (.5%)
Vomiting
70 (.49%)
Weight Decreased
70 (.49%)
Oedema
69 (.48%)
Neutrophil Count Increased
68 (.47%)
Overdose
68 (.47%)
Pruritus
67 (.47%)
Asthenia
66 (.46%)
Confusional State
65 (.45%)
Diabetes Mellitus
65 (.45%)
Haemoptysis
64 (.44%)
Lactic Acidosis
64 (.44%)
General Physical Health Deteriorati...
63 (.44%)
Cardiac Failure
62 (.43%)
Dyspnoea Exertional
61 (.42%)
Lower Respiratory Tract Infection
61 (.42%)
Dissociation
59 (.41%)
Hiatus Hernia
59 (.41%)
Iron Deficiency Anaemia
59 (.41%)
Skin Disorder
59 (.41%)
Abdominal Tenderness
58 (.4%)
Muscular Weakness
58 (.4%)
Staphylococcal Infection
58 (.4%)
Drug Eruption
57 (.4%)
Hypoglycaemia
57 (.4%)
Mean Cell Volume Decreased
57 (.4%)
Hypoxia
56 (.39%)
Alveolitis
55 (.38%)
Body Mass Index Decreased
55 (.38%)
Oropharyngeal Pain
55 (.38%)
Respiratory Failure
55 (.38%)
Dermatomyositis
54 (.38%)
Orthostatic Hypotension
54 (.38%)
Hypokalaemia
53 (.37%)
Monocyte Count Increased
53 (.37%)
Acute Respiratory Distress Syndrome
52 (.36%)
Anorexia
50 (.35%)
Cytolytic Hepatitis
50 (.35%)
Headache
50 (.35%)
Blood Pressure Increased
48 (.33%)
Dysphagia
48 (.33%)
Syncope
48 (.33%)
Condition Aggravated
47 (.33%)
Eosinophilia
46 (.32%)
Agranulocytosis
44 (.31%)
Toxic Skin Eruption
44 (.31%)
Decreased Appetite
43 (.3%)
White Blood Cell Disorder
42 (.29%)
Physical Assault
41 (.29%)
Interstitial Lung Disease
40 (.28%)
Shock
40 (.28%)
International Normalised Ratio Incr...
39 (.27%)
Pancreatitis Acute
39 (.27%)
Rhabdomyolysis
39 (.27%)
Abdominal Pain
38 (.26%)
Cardiac Arrest
38 (.26%)
Alanine Aminotransferase Increased
37 (.26%)
Anuria
37 (.26%)
Aortic Dissection
37 (.26%)
Renal Impairment
36 (.25%)
Renal Tubular Necrosis
36 (.25%)
Aspartate Aminotransferase Increase...
35 (.24%)
Myalgia
35 (.24%)
Coma
34 (.24%)
Anaemia
33 (.23%)

ExportShare/Embed GraphExport Export Data

This graph shows the top adverse events submitted to the FDA for Perindopril, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Perindopril is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Perindopril

What are the most common Perindopril adverse events reported to the FDA?

Show More Show More

ExportShare/Embed Graph Export Export Data

This graph shows the top categories of adverse events submitted to the FDA for Perindopril, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Perindopril is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Perindopril According to Those Reporting Adverse Events

Why are people taking Perindopril, according to those reporting adverse events to the FDA?

Hypertension
2205
Drug Use For Unknown Indication
776
Product Used For Unknown Indication
575
Ill-defined Disorder
232
Cardiac Failure Congestive
155
Essential Hypertension
149
Show More Show More
Cardiac Failure
135
Blood Pressure
66
Prophylaxis
57
Myocardial Ischaemia
53
Myocardial Infarction
44
Coronary Artery Disease
38
Blood Pressure Increased
32
Cardiac Disorder
24
Atrial Fibrillation
22
Angina Pectoris
17
Congestive Cardiomyopathy
16
Cardiac Failure Chronic
13
Overdose
13
Cardiomyopathy
12
Cerebrovascular Accident
11
Cerebrovascular Accident Prophylaxi...
11
Cardiovascular Event Prophylaxis
10
Unevaluable Event
10
Blood Pressure Abnormal
9
Left Ventricular Failure
8
Acute Myocardial Infarction
8
Ejection Fraction Decreased
8
Ischaemic Cardiomyopathy
8
Chest Pain
8
Arrhythmia Prophylaxis
7
Maternal Exposure Timing Unspecifie...
7
Cardiovascular Disorder
7
Nephropathy
7
Drug Exposure During Pregnancy
6
Thrombosis Prophylaxis
5
Transient Ischaemic Attack
5
Hypotension
5
Aortic Bypass
5
Diabetic Nephropathy
5
Hypertensive Heart Disease
5
Blood Pressure Management
5
Coronary Angioplasty
5
Renal Disorder
4
Acute Coronary Syndrome
4
Microalbuminuria
4
Hiv Infection
3
Infarction
3
Mental Disorder
3
Diabetes Mellitus
3
Gout
3

Drug Labels

LabelLabelerEffective
Perindopril ErbumineAurobindo Pharma Limited11-NOV-09
Perindopril ErbumineLupin Pharmaceuticals, Inc01-JAN-10
AceonAbbott Products, Inc.02-SEP-11
Perindopril ErbumineAurobindo Pharma Limited17-MAY-12
Perindopril ErbumineRoxane Laboratories, Inc.31-MAY-12
AceonXOMA (US) LLC11-MAR-13

Perindopril Case Reports

What Perindopril safety concerns are being reported by doctors and researchers in the medical literature?

Powered by Google

About Results

This report contains aggregated drug side effects and adverse events for Perindopril. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

Comments

Share your experience with Perindopril.