NIFEDIPINE

Nifedipine Adverse Events Reported to the FDA Over Time

How are Nifedipine adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Nifedipine, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Nifedipine is flagged as the suspect drug causing the adverse event.

Most Common Nifedipine Adverse Events Reported to the FDA

What are the most common Nifedipine adverse events reported to the FDA?

Hypotension	237 (2.33%)
Drug Exposure During Pregnancy	175 (1.72%)
Dizziness	166 (1.63%)
Drug Ineffective	165 (1.62%)
Blood Pressure Increased	152 (1.49%)
Drug Interaction	130 (1.28%)
Headache	121 (1.19%)
Completed Suicide	117 (1.15%)
Oedema Peripheral	116 (1.14%)
Dyspnoea	111 (1.09%)
Hypertension	111 (1.09%)
	Show More
Cardiac Arrest	107 (1.05%)
Malaise	107 (1.05%)
Bradycardia	89 (.87%)
Palpitations	87 (.85%)
Overdose	86 (.84%)
Nausea	84 (.83%)
Asthenia	76 (.75%)
Shock	72 (.71%)
Chest Pain	68 (.67%)
Caesarean Section	65 (.64%)
Premature Baby	64 (.63%)
Blood Pressure Decreased	62 (.61%)
Hypoxia	61 (.6%)
Vomiting	61 (.6%)
Condition Aggravated	60 (.59%)
Renal Failure Acute	59 (.58%)
Blood Pressure Inadequately Control...	58 (.57%)
Heart Rate Increased	58 (.57%)
Fatigue	57 (.56%)
Pulmonary Oedema	57 (.56%)
Multi-organ Failure	56 (.55%)
Metabolic Acidosis	51 (.5%)
Renal Failure	51 (.5%)
Loss Of Consciousness	50 (.49%)
Confusional State	46 (.45%)
Drug Toxicity	45 (.44%)
Drug Effect Decreased	42 (.41%)
Intra-uterine Death	42 (.41%)
Tachycardia	42 (.41%)
Depressed Level Of Consciousness	41 (.4%)
Medication Residue	39 (.38%)
Abdominal Pain	38 (.37%)
Suicide Attempt	38 (.37%)
Flushing	36 (.35%)
Feeling Abnormal	35 (.34%)
Rash	35 (.34%)
Back Pain	34 (.33%)
Multiple Drug Overdose	34 (.33%)
Orthostatic Hypotension	34 (.33%)
Rhabdomyolysis	34 (.33%)
Syncope	34 (.33%)
Erythema	33 (.32%)
Respiratory Arrest	33 (.32%)
Alanine Aminotransferase Increased	32 (.31%)
Oedema	31 (.3%)
Pyrexia	31 (.3%)
Acute Pulmonary Oedema	30 (.29%)
Blood Creatinine Increased	30 (.29%)
Cardiac Failure	30 (.29%)
Jaundice	30 (.29%)
Muscle Spasms	30 (.29%)
Musculoskeletal Stiffness	29 (.28%)
Myocardial Infarction	29 (.28%)
Blood Pressure Systolic Increased	28 (.28%)
Muscular Weakness	28 (.28%)
Arrhythmia	27 (.27%)
Blood Potassium Decreased	27 (.27%)
Lactic Acidosis	27 (.27%)
Pain	27 (.27%)
Pruritus	27 (.27%)
Sinus Tachycardia	27 (.27%)
Angina Pectoris	26 (.26%)
Atrial Fibrillation	26 (.26%)
Diarrhoea	26 (.26%)
Hypoglycaemia	26 (.26%)
Cardio-respiratory Arrest	25 (.25%)
Constipation	25 (.25%)
Cyanosis	25 (.25%)
Death	25 (.25%)
Pleural Effusion	25 (.25%)
Renal Impairment	25 (.25%)
Somnolence	25 (.25%)
Arthralgia	24 (.24%)
Chest Discomfort	24 (.24%)
Convulsion	24 (.24%)
Cough	24 (.24%)
No Therapeutic Response	24 (.24%)
Paraesthesia	24 (.24%)
Aspartate Aminotransferase Increase...	23 (.23%)
Dysgeusia	23 (.23%)
Intentional Overdose	23 (.23%)
Toxic Epidermal Necrolysis	23 (.23%)
Tremor	23 (.23%)
Anxiety	22 (.22%)
Blood Glucose Increased	22 (.22%)
Dialysis	22 (.22%)
Heart Rate Irregular	22 (.22%)
Joint Swelling	22 (.22%)
Pancreatic Carcinoma	22 (.22%)
Premature Labour	22 (.22%)

Share/Embed Graph Export Data

This graph shows the top adverse events submitted to the FDA for Nifedipine, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Nifedipine is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Nifedipine

What are the most common Nifedipine adverse events reported to the FDA?

Neurological	583 (5.73%)
Cardiac Arrhythmias	552 (5.42%)
Cardiac And Vascular Investigations	488 (4.79%)
Decreased And Nonspecific Blood Pre...	454 (4.46%)
Therapeutic And Nontherapeutic Effe...	424 (4.16%)
Respiratory	401 (3.94%)
Gastrointestinal Signs	304 (2.99%)
Chemical Injury And Poisoning	267 (2.62%)
Epidermal And Dermal Conditions	264 (2.59%)
Medication Errors	236 (2.32%)
Renal Disorders	191 (1.88%)
	Show More
Suicidal And Self-injurious Behavio...	164 (1.61%)
Cardiac Disorder Signs	133 (1.31%)
Muscle	133 (1.31%)
Lower Respiratory Tract Disorders	130 (1.28%)
Headaches	128 (1.26%)
Coronary Artery	122 (1.2%)
Vascular Hypertensive	122 (1.2%)
Musculoskeletal And Connective Tiss...	104 (1.02%)
Electrolyte And Fluid Balance Condi...	99 (.97%)
Infections - Pathogen Unspecified	98 (.96%)
Neonatal And Perinatal Conditions	97 (.95%)
Hepatic And Hepatobiliary	92 (.9%)
Central Nervous System Vascular	91 (.89%)
Hepatobiliary	90 (.88%)
Product Quality Issues	90 (.88%)
Acid-base	87 (.85%)
Gastrointestinal Motility And Defec...	84 (.83%)
Hematology Investigations	84 (.83%)
Physical Examination Topics	82 (.81%)
Renal And Urinary Tract Investigati...	82 (.81%)
Vascular	80 (.79%)
Obstetric And Gynecological Therape...	76 (.75%)
Metabolic, Nutritional And Blood Ga...	75 (.74%)
Enzyme	73 (.72%)
Myocardial	69 (.68%)
Deliria	67 (.66%)
Heart Failures	67 (.66%)
Joint	67 (.66%)
Movement Disorders	67 (.66%)
Glucose Metabolism Disorders	64 (.63%)
Anxiety Disorders	56 (.55%)
Lifestyle Issues	56 (.55%)
Dental And Gingival Conditions	54 (.53%)
Water, Electrolyte And Mineral	52 (.51%)
Allergic Conditions	51 (.5%)
Anemias Nonhemolytic And Marrow Dep...	51 (.5%)
Arteriosclerosis, Stenosis, Vascula...	51 (.5%)
Vision	49 (.48%)
Urinary Tract Signs	47 (.46%)
Abortions And Stillbirth	46 (.45%)
White Blood Cell	46 (.45%)
Hematological And Lymphoid Tissue T...	44 (.43%)
Seizures	44 (.43%)
Injuries	43 (.42%)
Body Temperature Conditions	38 (.37%)
Maternal Complications Of Labour An...	36 (.35%)
Connective Tissue Disorders	35 (.34%)
Gastrointestinal Conditions	35 (.34%)
Psychiatric	35 (.34%)
Fetal Complications	32 (.31%)
Gastrointestinal Stenosis And Obstr...	32 (.31%)
Appetite And General Nutritional	31 (.3%)
Bacterial Infectious	31 (.3%)
Placental, Amniotic And Cavity Diso...	31 (.3%)
Pleural	31 (.3%)
Skin Appendage Conditions	31 (.3%)
Fatal Outcomes	29 (.28%)
Platelet	29 (.28%)
Procedural And Device Related Injur...	28 (.28%)
Sleep Disorders	28 (.28%)
Gallbladder	27 (.27%)
Mood Disorders	27 (.27%)
Toxicology And Therapeutic Drug Mon...	27 (.27%)
Bronchial Disorders	26 (.26%)
Gastrointestinal Neoplasms Malignan...	26 (.26%)
Upper Respiratory Tract Disorders	26 (.26%)
Nephropathies	25 (.25%)
Therapeutic Procedures And Supporti...	25 (.25%)
Maternal Complications Of Pregnancy	23 (.23%)
Neonatal Respiratory	22 (.22%)
Neuromuscular	22 (.22%)
Oral Soft Tissue Conditions	22 (.22%)
Bone, Calcium, Magnesium And Phosph...	21 (.21%)
Depressed Mood Disorders	21 (.21%)
Exocrine Pancreas Conditions	20 (.2%)
Gastrointestinal Hemorrhages	19 (.19%)
Pregnancy, Labour, Delivery And Pos...	19 (.19%)
Protein And Chemistry Analyses	19 (.19%)
Lipid Analyses	18 (.18%)
Gastrointestinal Ulceration And Per...	17 (.17%)
Gastrointestinal Vascular Condition...	17 (.17%)
Skin Vascular Abnormalities	15 (.15%)
Investigations, Imaging And Histopa...	14 (.14%)
Peritoneal And Retroperitoneal Cond...	14 (.14%)
Pulmonary Vascular	14 (.14%)
Spinal Cord And Nerve Root	14 (.14%)
Angiedema And Urticaria	13 (.13%)
Eye	13 (.13%)
Gastrointestinal Inflammatory Condi...	13 (.13%)
Gastrointestinal Tract Disorders Co...	13 (.13%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Nifedipine, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Nifedipine is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.