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Merrem Adverse Events Reported to the FDA Over Time

How are Merrem adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Merrem, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Merrem is flagged as the suspect drug causing the adverse event.

Most Common Merrem Adverse Events Reported to the FDA

What are the most common Merrem adverse events reported to the FDA?

Convulsion
24 (5.21%)
Rash
13 (2.82%)
Skin Exfoliation
13 (2.82%)
Stevens-johnson Syndrome
12 (2.6%)
Drug Interaction
11 (2.39%)
Death
10 (2.17%)
Pyrexia
10 (2.17%)
Rash Generalised
10 (2.17%)
Rash Maculo-papular
10 (2.17%)
Erythema
7 (1.52%)
Neutropenia
7 (1.52%)
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Pruritus
7 (1.52%)
Cardiac Arrest
6 (1.3%)
Agnosia
5 (1.08%)
Agranulocytosis
5 (1.08%)
Anticonvulsant Drug Level Decreased
5 (1.08%)
Deafness
5 (1.08%)
Infection
5 (1.08%)
Renal Failure Acute
5 (1.08%)
Thrombocytopenia
5 (1.08%)
Tremor
5 (1.08%)
Chills
4 (.87%)
Dermatitis Bullous
4 (.87%)
Diarrhoea
4 (.87%)
Dyspnoea
4 (.87%)
Electrolyte Imbalance
4 (.87%)
Face Oedema
4 (.87%)
Headache
4 (.87%)
Hypersensitivity
4 (.87%)
Malaise
4 (.87%)
Nausea
4 (.87%)
Rhabdomyolysis
4 (.87%)
Tooth Discolouration
4 (.87%)
Accidental Overdose
3 (.65%)
Anaphylactic Reaction
3 (.65%)
Bone Marrow Failure
3 (.65%)
Drug Ineffective
3 (.65%)
Drug Level Decreased
3 (.65%)
Drug Level Increased
3 (.65%)
Dysuria
3 (.65%)
Eosinophil Count Increased
3 (.65%)
Hepatitis
3 (.65%)
Hepatotoxicity
3 (.65%)
Leukocytoclastic Vasculitis
3 (.65%)
Leukopenia
3 (.65%)
Pain
3 (.65%)
Sepsis
3 (.65%)
Urticaria
3 (.65%)
Abdominal Infection
2 (.43%)
Anaemia
2 (.43%)
Angioedema
2 (.43%)
Apnoea
2 (.43%)
Balance Disorder
2 (.43%)
Bedridden
2 (.43%)
Blister
2 (.43%)
Bradycardia
2 (.43%)
Cholestasis
2 (.43%)
Complex Partial Seizures
2 (.43%)
Constipation
2 (.43%)
Dysphagia
2 (.43%)
Eosinophilia
2 (.43%)
Grand Mal Convulsion
2 (.43%)
Heart Rate Increased
2 (.43%)
Hypertransaminasaemia
2 (.43%)
Idiopathic Pulmonary Fibrosis
2 (.43%)
Infusion Related Reaction
2 (.43%)
Injection Site Necrosis
2 (.43%)
Jaundice
2 (.43%)
Laceration
2 (.43%)
Laryngeal Oedema
2 (.43%)
Liver Disorder
2 (.43%)
Medication Error
2 (.43%)
Palpitations
2 (.43%)
Pathogen Resistance
2 (.43%)
Platelet Count Decreased
2 (.43%)
Post Procedural Infection
2 (.43%)
Postural Orthostatic Tachycardia Sy...
2 (.43%)
Rash Macular
2 (.43%)
Renal Failure
2 (.43%)
Skin Lesion
2 (.43%)
Status Epilepticus
2 (.43%)
White Blood Cell Count Decreased
2 (.43%)
Abdominal Pain
1 (.22%)
Abscess
1 (.22%)
Actinic Keratosis
1 (.22%)
Ageusia
1 (.22%)
Agitation
1 (.22%)
Atonic Seizures
1 (.22%)
Atrial Fibrillation
1 (.22%)
Bacteraemia
1 (.22%)
Blood Alkaline Phosphatase Increase...
1 (.22%)
Blood Amylase Increased
1 (.22%)
Blood Creatinine Increased
1 (.22%)
Blood Pressure Increased
1 (.22%)
Body Temperature Increased
1 (.22%)
Bronchiectasis
1 (.22%)
Bronchospasm
1 (.22%)
Cardiac Disorder
1 (.22%)
Cardiac Failure
1 (.22%)
Catheter Related Complication
1 (.22%)
Choking
1 (.22%)

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This graph shows the top adverse events submitted to the FDA for Merrem, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Merrem is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Merrem

What are the most common Merrem adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Merrem, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Merrem is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Merrem According to Those Reporting Adverse Events

Why are people taking Merrem, according to those reporting adverse events to the FDA?

Sepsis
17
Product Used For Unknown Indication
16
Infection
15
Drug Use For Unknown Indication
11
Pneumonia
9
Brain Abscess
7
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Pyrexia
6
Pseudomonas Infection
6
Bronchopneumonia
5
Encephalitis
5
Antibiotic Prophylaxis
5
Respiratory Tract Infection
4
Febrile Neutropenia
4
Staphylococcal Infection
4
Urinary Tract Infection
4
Bacteraemia
3
Abdominal Abscess
3
Cystic Fibrosis
3
Klebsiella Sepsis
3
Antibiotic Therapy
3
Cellulitis
2
Infection Prophylaxis
2
Chronic Sinusitis
2
Cerebral Haemorrhage
2
Urinary Tract Infection Pseudomonal
2
Bacterial Sepsis
2
Postoperative Wound Infection
2
Nosocomial Infection
2
Peritonitis
2
Pneumonitis
2
Sinusitis
2
Urosepsis
2
Neutropenia
2
Osteomyelitis
2
Urinary Tract Infection Bacterial
1
Peritonitis Bacterial
1
Pyelonephritis
1
Postoperative Infection
1
Klebsiella Infection
1
Bacterial Infection
1
Osteomyelitis Bacterial
1
Blood Culture Positive
1
Staphylococcal Sepsis
1
Infected Skin Ulcer
1
Escherichia Infection
1
Sputum Culture Positive
1
Lymphoma
1
Abscess
1
Cholecystitis Acute
1
Liver Abscess
1
Periarthritis
1

Drug Labels

LabelLabelerEffective
MerremivAstraZeneca Pharmaceuticals LP28-MAR-13

Merrem Case Reports

What Merrem safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Merrem. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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