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Meropen Adverse Events Reported to the FDA Over Time

How are Meropen adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Meropen, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Meropen is flagged as the suspect drug causing the adverse event.

Most Common Meropen Adverse Events Reported to the FDA

What are the most common Meropen adverse events reported to the FDA?

Hepatic Function Abnormal
88 (3.46%)
Liver Disorder
68 (2.67%)
Pyrexia
63 (2.48%)
Interstitial Lung Disease
56 (2.2%)
Platelet Count Decreased
46 (1.81%)
Renal Impairment
45 (1.77%)
Disseminated Intravascular Coagulat...
42 (1.65%)
Aspartate Aminotransferase Increase...
40 (1.57%)
Pneumonia
38 (1.49%)
Alanine Aminotransferase Increased
35 (1.38%)
Sepsis
35 (1.38%)
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Rash
33 (1.3%)
Gamma-glutamyltransferase Increased
29 (1.14%)
Blood Urea Increased
27 (1.06%)
Renal Failure
27 (1.06%)
White Blood Cell Count Decreased
27 (1.06%)
Blood Creatinine Increased
26 (1.02%)
Drug Eruption
26 (1.02%)
Blood Alkaline Phosphatase Increase...
25 (.98%)
Toxic Epidermal Necrolysis
21 (.83%)
Blood Lactate Dehydrogenase Increas...
20 (.79%)
Depressed Level Of Consciousness
20 (.79%)
Anaemia
19 (.75%)
Blood Bilirubin Increased
19 (.75%)
Multi-organ Failure
19 (.75%)
Pancytopenia
19 (.75%)
Blood Pressure Decreased
18 (.71%)
C-reactive Protein Increased
18 (.71%)
Renal Disorder
18 (.71%)
Shock
18 (.71%)
Respiratory Failure
17 (.67%)
White Blood Cell Count Increased
17 (.67%)
Dyspnoea
16 (.63%)
Thrombocytopenia
16 (.63%)
Haemolytic Anaemia
15 (.59%)
Renal Failure Acute
15 (.59%)
Anaphylactic Shock
14 (.55%)
Drug Rash With Eosinophilia And Sys...
14 (.55%)
Septic Shock
14 (.55%)
Agranulocytosis
13 (.51%)
Hepatic Failure
13 (.51%)
Dizziness
12 (.47%)
Neutrophil Count Decreased
12 (.47%)
Oxygen Saturation Decreased
12 (.47%)
Acute Respiratory Distress Syndrome
11 (.43%)
Condition Aggravated
11 (.43%)
Eosinophilia
11 (.43%)
Erythema
11 (.43%)
Haemoglobin Decreased
11 (.43%)
Infection
11 (.43%)
Leukopenia
11 (.43%)
Anuria
10 (.39%)
Blister
10 (.39%)
Bone Marrow Failure
10 (.39%)
Drug Hypersensitivity
10 (.39%)
Drug Level Increased
10 (.39%)
Feeling Abnormal
10 (.39%)
Haemodialysis
10 (.39%)
Hiccups
10 (.39%)
Staphylococcal Infection
10 (.39%)
Cardiac Failure
9 (.35%)
Cystitis Haemorrhagic
9 (.35%)
Dyskinesia
9 (.35%)
Haematocrit Decreased
9 (.35%)
Malaise
9 (.35%)
Oliguria
9 (.35%)
Pulmonary Haemorrhage
9 (.35%)
Stevens-johnson Syndrome
9 (.35%)
Altered State Of Consciousness
8 (.31%)
Cardio-respiratory Arrest
8 (.31%)
Death
8 (.31%)
Dermatitis Exfoliative
8 (.31%)
Hypokalaemia
8 (.31%)
Hyponatraemia
8 (.31%)
Lung Disorder
8 (.31%)
Lymphocyte Count Decreased
8 (.31%)
Nausea
8 (.31%)
Pancreatitis Acute
8 (.31%)
Vomiting
8 (.31%)
Wheezing
8 (.31%)
Anaphylactic Reaction
7 (.28%)
Bronchopulmonary Aspergillosis
7 (.28%)
Dehydration
7 (.28%)
Drug Interaction
7 (.28%)
Gastrointestinal Haemorrhage
7 (.28%)
General Physical Health Deteriorati...
7 (.28%)
Granulocytopenia
7 (.28%)
Heart Rate Decreased
7 (.28%)
Histiocytosis Haematophagic
7 (.28%)
Hypoalbuminaemia
7 (.28%)
Jaundice
7 (.28%)
Liver Function Test Abnormal
7 (.28%)
Myocardial Infarction
7 (.28%)
Oculomucocutaneous Syndrome
7 (.28%)
Red Blood Cell Count Decreased
7 (.28%)
Tumour Lysis Syndrome
7 (.28%)
Urticaria
7 (.28%)
Acute Generalised Exanthematous Pus...
6 (.24%)
Acute Graft Versus Host Disease
6 (.24%)
Acute Respiratory Failure
6 (.24%)
Body Temperature Increased
6 (.24%)

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This graph shows the top adverse events submitted to the FDA for Meropen, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Meropen is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Meropen

What are the most common Meropen adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Meropen, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Meropen is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Meropen According to Those Reporting Adverse Events

Why are people taking Meropen, according to those reporting adverse events to the FDA?

Pneumonia
201
Sepsis
81
Infection
70
Pyrexia
57
Drug Use For Unknown Indication
47
Febrile Neutropenia
29
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Infection Prophylaxis
24
Pneumonia Bacterial
18
Prophylaxis
18
Peritonitis
16
Urinary Tract Infection
16
Pneumonia Aspiration
15
Pancreatitis Acute
11
Meningitis Bacterial
11
Antibiotic Prophylaxis
9
Pseudomonas Infection
9
Meningitis
9
Bacterial Infection
8
Disseminated Intravascular Coagulat...
8
Pyelonephritis
7
Cellulitis
6
Bronchopulmonary Aspergillosis
6
Antibiotic Therapy
6
Product Used For Unknown Indication
6
Fungal Infection
6
Brain Abscess
5
Malaise
5
Acute Lymphocytic Leukaemia
5
Pneumonia Staphylococcal
4
Urosepsis
4
Liver Abscess
4
Cholecystitis
4
Inflammation
3
Septic Shock
3
Escherichia Bacteraemia
3
Aspergillosis
3
Altered State Of Consciousness
3
Cholangitis
3
Lung Abscess
3
Ill-defined Disorder
3
C-reactive Protein Increased
3
Pancreatitis
3
Pyelonephritis Acute
3
Agranulocytosis
3
Post Procedural Infection
3
Type 2 Diabetes Mellitus
3
Enteritis Infectious
3
Pleurisy
2
Encephalitis
2
Pneumonia Pneumococcal
2
Serratia Infection
2

Meropen Case Reports

What Meropen safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Meropen. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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