LOVASTATIN

Lovastatin Adverse Events Reported to the FDA Over Time

How are Lovastatin adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Lovastatin, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Lovastatin is flagged as the suspect drug causing the adverse event.

Most Common Lovastatin Adverse Events Reported to the FDA

What are the most common Lovastatin adverse events reported to the FDA?

Myalgia	129 (3.5%)
Rhabdomyolysis	105 (2.85%)
Drug Interaction	72 (1.95%)
Asthenia	64 (1.74%)
Arthralgia	61 (1.66%)
Fatigue	58 (1.57%)
Muscle Spasms	56 (1.52%)
Pain In Extremity	56 (1.52%)
Completed Suicide	55 (1.49%)
Blood Creatine Phosphokinase Increa...	49 (1.33%)
Muscular Weakness	45 (1.22%)
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Dizziness	38 (1.03%)
Pain	36 (.98%)
Nausea	34 (.92%)
Headache	32 (.87%)
Insomnia	32 (.87%)
Gait Disturbance	31 (.84%)
Drug Ineffective	27 (.73%)
Dyspnoea	26 (.71%)
Renal Failure Acute	26 (.71%)
Renal Failure	25 (.68%)
Back Pain	24 (.65%)
Chest Pain	24 (.65%)
Feeling Abnormal	24 (.65%)
Abasia	23 (.62%)
Abdominal Pain Upper	22 (.6%)
Myopathy	22 (.6%)
Oedema Peripheral	22 (.6%)
Alanine Aminotransferase Increased	19 (.52%)
Blood Cholesterol Increased	19 (.52%)
Diarrhoea	19 (.52%)
Pyrexia	19 (.52%)
Amnesia	18 (.49%)
Anxiety	18 (.49%)
Aspartate Aminotransferase Increase...	18 (.49%)
Drug Toxicity	18 (.49%)
Malaise	18 (.49%)
Memory Impairment	18 (.49%)
Muscle Injury	18 (.49%)
Constipation	17 (.46%)
Hypoaesthesia	17 (.46%)
Loss Of Consciousness	17 (.46%)
Medication Error	17 (.46%)
Pruritus	17 (.46%)
Weight Decreased	17 (.46%)
Amyotrophic Lateral Sclerosis	16 (.43%)
Blood Glucose Increased	16 (.43%)
Hepatitis	16 (.43%)
Liver Function Test Abnormal	16 (.43%)
Paraesthesia	16 (.43%)
Activities Of Daily Living Impaired	15 (.41%)
Hepatic Enzyme Increased	15 (.41%)
Mental Status Changes	15 (.41%)
Suicidal Ideation	15 (.41%)
Tremor	15 (.41%)
Urticaria	15 (.41%)
Akathisia	14 (.38%)
Chromaturia	14 (.38%)
Fall	14 (.38%)
Physical Assault	14 (.38%)
Poisoning	14 (.38%)
Vomiting	14 (.38%)
Abdominal Pain	13 (.35%)
Blood Creatinine Increased	13 (.35%)
Blood Pressure Increased	13 (.35%)
Confusional State	13 (.35%)
Depression	13 (.35%)
Rash	13 (.35%)
Vision Blurred	13 (.35%)
Cardiac Arrest	12 (.33%)
Hepatic Steatosis	12 (.33%)
Liver Disorder	12 (.33%)
Muscle Disorder	12 (.33%)
Alopecia	11 (.3%)
Cardiac Failure Congestive	11 (.3%)
Death	11 (.3%)
Dry Mouth	11 (.3%)
Dyskinesia	11 (.3%)
Hyperkalaemia	11 (.3%)
Myocardial Infarction	11 (.3%)
Palpitations	11 (.3%)
Aggression	10 (.27%)
Catheter Sepsis	10 (.27%)
Coagulopathy	10 (.27%)
Movement Disorder	10 (.27%)
Neuropathy Peripheral	10 (.27%)
Pneumonia	10 (.27%)
Staphylococcal Sepsis	10 (.27%)
Swelling Face	10 (.27%)
Systemic Lupus Erythematosus	10 (.27%)
Thinking Abnormal	10 (.27%)
Anaemia	9 (.24%)
Arthropathy	9 (.24%)
Coma	9 (.24%)
Condition Aggravated	9 (.24%)
Cough	9 (.24%)
Drug Hypersensitivity	9 (.24%)
Hypertension	9 (.24%)
Hypotension	9 (.24%)
Mastication Disorder	9 (.24%)
Pancreatitis	9 (.24%)

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This graph shows the top adverse events submitted to the FDA for Lovastatin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Lovastatin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Lovastatin

What are the most common Lovastatin adverse events reported to the FDA?

Muscle	390 (10.58%)
Neurological	194 (5.26%)
Musculoskeletal And Connective Tiss...	121 (3.28%)
Therapeutic And Nontherapeutic Effe...	117 (3.18%)
Gastrointestinal Signs	115 (3.12%)
Joint	83 (2.25%)
Hepatic And Hepatobiliary	81 (2.2%)
Hepatobiliary	81 (2.2%)
Epidermal And Dermal Conditions	80 (2.17%)
Renal Disorders	74 (2.01%)
Suicidal And Self-injurious Behavio...	74 (2.01%)
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Respiratory	69 (1.87%)
Enzyme	61 (1.66%)
Injuries	60 (1.63%)
Movement Disorders	59 (1.6%)
Medication Errors	53 (1.44%)
Sleep Disorders	52 (1.41%)
Cardiac Arrhythmias	50 (1.36%)
Infections - Pathogen Unspecified	50 (1.36%)
Gastrointestinal Motility And Defec...	49 (1.33%)
Mental Impairment	45 (1.22%)
Anxiety Disorders	41 (1.11%)
Chemical Injury And Poisoning	40 (1.09%)
Lifestyle Issues	39 (1.06%)
Lipid Analyses	37 (1%)
Urinary Tract Signs	35 (.95%)
Headaches	33 (.9%)
Cardiac And Vascular Investigations	30 (.81%)
Physical Examination Topics	29 (.79%)
Renal And Urinary Tract Investigati...	28 (.76%)
Vision	27 (.73%)
Neuromuscular	26 (.71%)
Electrolyte And Fluid Balance Condi...	25 (.68%)
Psychiatric	25 (.68%)
Appetite And General Nutritional	24 (.65%)
Metabolic, Nutritional And Blood Ga...	24 (.65%)
Water, Electrolyte And Mineral	23 (.62%)
Oral Soft Tissue Conditions	22 (.6%)
Angiedema And Urticaria	21 (.57%)
Bacterial Infectious	21 (.57%)
Coronary Artery	20 (.54%)
Deliria	20 (.54%)
Body Temperature Conditions	19 (.52%)
Hematology Investigations	19 (.52%)
Skin Appendage Conditions	18 (.49%)
Vascular	18 (.49%)
Viral Infectious	16 (.43%)
Anemias Nonhemolytic And Marrow Dep...	15 (.41%)
Bone Disorders	15 (.41%)
Decreased And Nonspecific Blood Pre...	15 (.41%)
Depressed Mood Disorders	15 (.41%)
Disturbances In Thinking	15 (.41%)
Legal Issues	15 (.41%)
Peripheral Neuropathies	15 (.41%)
Allergic Conditions	14 (.38%)
Central Nervous System Vascular	14 (.38%)
Heart Failures	14 (.38%)
Personality Disorders	13 (.35%)
Salivary Gland Conditions	13 (.35%)
Bone And Joint Injuries	12 (.33%)
Cardiac Disorder Signs	12 (.33%)
Connective Tissue Disorders	12 (.33%)
Fatal Outcomes	11 (.3%)
Mood Disorders	11 (.3%)
Myocardial	11 (.3%)
Coagulopathies And Bleeding Diathes...	10 (.27%)
Vascular Hypertensive	10 (.27%)
Exocrine Pancreas Conditions	9 (.24%)
Glucose Metabolism Disorders	9 (.24%)
Lower Respiratory Tract Disorders	9 (.24%)
Tendon, Ligament And Cartilage	9 (.24%)
Upper Respiratory Tract Disorders	9 (.24%)
Immunology And Allergy	8 (.22%)
Musculoskeletal And Connective Tiss...	8 (.22%)
Neurological Disorders Congenital	8 (.22%)
Arteriosclerosis, Stenosis, Vascula...	7 (.19%)
Endocrine Investigations	7 (.19%)
Gastrointestinal Conditions	7 (.19%)
Tissue	7 (.19%)
Tongue Conditions	7 (.19%)
Administration Site Reactions	6 (.16%)
Bronchial Disorders	6 (.16%)
Changes In Physical Activity	6 (.16%)
Dental And Gingival Conditions	6 (.16%)
Gastrointestinal Ulceration And Per...	6 (.16%)
Hematological And Lymphoid Tissue T...	6 (.16%)
Investigations, Imaging And Histopa...	6 (.16%)
Platelet	6 (.16%)
Product Quality Issues	6 (.16%)
Pulmonary Vascular	6 (.16%)
Sexual Function And Fertility	6 (.16%)
Sleep Disturbances	6 (.16%)
Spleen, Lymphatic And Reticulendoth...	6 (.16%)
Therapeutic Procedures And Supporti...	6 (.16%)
Toxicology And Therapeutic Drug Mon...	6 (.16%)
Acid-base	5 (.14%)
Aural	5 (.14%)
Congenital And Hereditary	5 (.14%)
Embolism And Thrombosis	5 (.14%)
Eye	5 (.14%)
Gastrointestinal Hemorrhages	5 (.14%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Lovastatin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Lovastatin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.