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LEVOMEPROMAZINE

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Levomepromazine Adverse Events Reported to the FDA Over Time

How are Levomepromazine adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Levomepromazine, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Levomepromazine is flagged as the suspect drug causing the adverse event.

Most Common Levomepromazine Adverse Events Reported to the FDA

What are the most common Levomepromazine adverse events reported to the FDA?

Drug Interaction
52 (2.68%)
Neuroleptic Malignant Syndrome
30 (1.55%)
Somnolence
28 (1.44%)
Drug Ineffective
23 (1.19%)
Confusional State
21 (1.08%)
Insomnia
21 (1.08%)
Drug Toxicity
19 (.98%)
Delirium
18 (.93%)
Hypothermia
18 (.93%)
Vomiting
18 (.93%)
Agitation
17 (.88%)
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Dehydration
16 (.83%)
Loss Of Consciousness
16 (.83%)
Overdose
16 (.83%)
Suicide Attempt
16 (.83%)
Tremor
16 (.83%)
Diarrhoea
15 (.77%)
Rhabdomyolysis
15 (.77%)
Cardio-respiratory Arrest
14 (.72%)
Drug Exposure During Pregnancy
14 (.72%)
Extrapyramidal Disorder
14 (.72%)
Pneumonia
14 (.72%)
Mesothelioma
13 (.67%)
Pneumonia Aspiration
13 (.67%)
Aggression
12 (.62%)
Anxiety
12 (.62%)
Convulsion
12 (.62%)
Dysarthria
12 (.62%)
Gait Disturbance
12 (.62%)
Ileus Paralytic
12 (.62%)
Pyrexia
12 (.62%)
Blood Creatine Phosphokinase Increa...
11 (.57%)
Completed Suicide
11 (.57%)
Irritability
11 (.57%)
Lung Neoplasm Malignant
11 (.57%)
Multiple Drug Overdose Intentional
11 (.57%)
Weight Decreased
11 (.57%)
Akathisia
10 (.52%)
Anaemia
10 (.52%)
Apathy
10 (.52%)
Coma
10 (.52%)
Decreased Appetite
10 (.52%)
Delusion
10 (.52%)
Hallucination
10 (.52%)
Intentional Overdose
10 (.52%)
Multiple Drug Overdose
10 (.52%)
Nausea
10 (.52%)
Suicidal Ideation
10 (.52%)
Agranulocytosis
9 (.46%)
Constipation
9 (.46%)
Death
9 (.46%)
Deep Vein Thrombosis
9 (.46%)
Disorientation
9 (.46%)
Dysphagia
9 (.46%)
Sudden Death
9 (.46%)
Tachycardia
9 (.46%)
Therapeutic Agent Toxicity
9 (.46%)
Depressed Level Of Consciousness
8 (.41%)
Drug Level Increased
8 (.41%)
Liver Disorder
8 (.41%)
Oliguria
8 (.41%)
Pulmonary Oedema
8 (.41%)
Schizophrenia
8 (.41%)
Serotonin Syndrome
8 (.41%)
Thrombocytopenia
8 (.41%)
Asthenia
7 (.36%)
Bedridden
7 (.36%)
Blood Creatinine Increased
7 (.36%)
Cachexia
7 (.36%)
Compartment Syndrome
7 (.36%)
Condition Aggravated
7 (.36%)
Consciousness Fluctuating
7 (.36%)
Dyskinesia
7 (.36%)
Dyspnoea
7 (.36%)
Hepatic Function Abnormal
7 (.36%)
Hyperhidrosis
7 (.36%)
Hypotension
7 (.36%)
Lethargy
7 (.36%)
Metastases To Liver
7 (.36%)
Pruritus
7 (.36%)
White Blood Cell Count Increased
7 (.36%)
Abdominal Pain
6 (.31%)
Blood Pressure Increased
6 (.31%)
Bradycardia
6 (.31%)
Caesarean Section
6 (.31%)
Catatonia
6 (.31%)
Circadian Rhythm Sleep Disorder
6 (.31%)
Cognitive Disorder
6 (.31%)
Disease Recurrence
6 (.31%)
Disturbance In Attention
6 (.31%)
Fall
6 (.31%)
Haemodialysis
6 (.31%)
Hypoglycaemia
6 (.31%)
Liver Function Test Abnormal
6 (.31%)
Malaise
6 (.31%)
Myocardial Infarction
6 (.31%)
Myoclonus
6 (.31%)
Platelet Count Decreased
6 (.31%)
Renal Failure Acute
6 (.31%)
Abdominal Distension
5 (.26%)
Arrhythmia
5 (.26%)

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This graph shows the top adverse events submitted to the FDA for Levomepromazine, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Levomepromazine is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Levomepromazine

What are the most common Levomepromazine adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Levomepromazine, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Levomepromazine is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Levomepromazine According to Those Reporting Adverse Events

Why are people taking Levomepromazine, according to those reporting adverse events to the FDA?

Schizophrenia
122
Drug Use For Unknown Indication
108
Product Used For Unknown Indication
65
Insomnia
53
Depression
28
Ill-defined Disorder
25
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Nausea
24
Psychotic Disorder
21
Sleep Disorder
15
Antiemetic Supportive Care
14
Schizophrenia, Paranoid Type
14
Bipolar I Disorder
12
Agitation
12
Anxiety
9
Mental Retardation Severity Unspeci...
8
Vomiting
8
Schizoaffective Disorder
7
Prophylaxis Of Nausea And Vomiting
7
Aggression
7
Delirium
5
Sedation
5
Mental Disorder
4
Restlessness
4
Delusion
4
Sleep Disorder Therapy
4
Hallucination
3
Sedative Therapy
3
Dementia Alzheimers Type
3
Autism
3
Impulsive Behaviour
3
Anxiety Disorder
3
Pain
3
Schizophreniform Disorder
2
Vitamin B12 Deficiency
2
Bipolar Disorder
2
Foetal Exposure During Pregnancy
2
Tension
2
Schizophrenia, Disorganised Type
2
Encephalitis Herpes
2
Cerebral Ischaemia
2
Affect Lability
2
Delusional Disorder, Unspecified Ty...
2
Borderline Personality Disorder
2
Frontotemporal Dementia
2
Antisocial Behaviour
1
Muscle Spasms
1
Depressed Mood
1
Multiple Drug Overdose
1
Mania
1
Irritability
1
Negativism
1

Levomepromazine Case Reports

What Levomepromazine safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Levomepromazine. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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