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LASILIX

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Lasilix Adverse Events Reported to the FDA Over Time

How are Lasilix adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Lasilix, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Lasilix is flagged as the suspect drug causing the adverse event.

Most Common Lasilix Adverse Events Reported to the FDA

What are the most common Lasilix adverse events reported to the FDA?

Renal Failure Acute
224 (4.5%)
Hyponatraemia
123 (2.47%)
Renal Failure
122 (2.45%)
Dehydration
110 (2.21%)
Drug Interaction
109 (2.19%)
Hyperkalaemia
108 (2.17%)
Fall
81 (1.63%)
Malaise
53 (1.06%)
Thrombocytopenia
53 (1.06%)
Blood Creatinine Increased
50 (1%)
Hypotension
48 (.96%)
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General Physical Health Deteriorati...
46 (.92%)
Hypokalaemia
45 (.9%)
Cardiac Failure
44 (.88%)
Bradycardia
42 (.84%)
Pruritus
41 (.82%)
Pyrexia
38 (.76%)
Anaemia
37 (.74%)
Condition Aggravated
36 (.72%)
Diarrhoea
36 (.72%)
Eosinophilia
34 (.68%)
Asthenia
33 (.66%)
Confusional State
33 (.66%)
Somnolence
33 (.66%)
Loss Of Consciousness
32 (.64%)
Vomiting
31 (.62%)
International Normalised Ratio Incr...
30 (.6%)
Dyspnoea
29 (.58%)
Alanine Aminotransferase Increased
28 (.56%)
Encephalopathy
28 (.56%)
Hypoglycaemia
26 (.52%)
Overdose
25 (.5%)
Haematoma
24 (.48%)
Oedema Peripheral
24 (.48%)
Disorientation
23 (.46%)
Atrial Fibrillation
22 (.44%)
Coma
22 (.44%)
Depressed Level Of Consciousness
22 (.44%)
Pancytopenia
22 (.44%)
Aspartate Aminotransferase Increase...
21 (.42%)
Blood Urea Increased
21 (.42%)
Interstitial Lung Disease
21 (.42%)
Lactic Acidosis
21 (.42%)
Rhabdomyolysis
20 (.4%)
Weight Decreased
20 (.4%)
Cytolytic Hepatitis
19 (.38%)
Rash Pustular
19 (.38%)
Acute Pulmonary Oedema
18 (.36%)
Drug Rash With Eosinophilia And Sys...
18 (.36%)
Eczema
18 (.36%)
Gamma-glutamyltransferase Increased
18 (.36%)
Hypertension
18 (.36%)
Neutropenia
18 (.36%)
Torsade De Pointes
18 (.36%)
Toxic Skin Eruption
18 (.36%)
Agranulocytosis
17 (.34%)
Blood Creatine Phosphokinase Increa...
17 (.34%)
Cholestasis
17 (.34%)
Hypochloraemia
17 (.34%)
Lung Disorder
17 (.34%)
Orthostatic Hypotension
17 (.34%)
Convulsion
16 (.32%)
Renal Impairment
16 (.32%)
Toxic Epidermal Necrolysis
16 (.32%)
Acute Generalised Exanthematous Pus...
15 (.3%)
Creatinine Renal Clearance Decrease...
15 (.3%)
Haemodialysis
15 (.3%)
Pulmonary Embolism
15 (.3%)
Purpura
15 (.3%)
Septic Shock
15 (.3%)
Abdominal Pain
14 (.28%)
Blood Alkaline Phosphatase Increase...
14 (.28%)
Cardiac Arrest
14 (.28%)
Leukocytosis
14 (.28%)
Anorexia
13 (.26%)
Cardiomegaly
13 (.26%)
Death
13 (.26%)
Inflammation
13 (.26%)
Jaundice
13 (.26%)
Pulmonary Fibrosis
13 (.26%)
Respiratory Distress
13 (.26%)
Syncope
13 (.26%)
Ascites
12 (.24%)
C-reactive Protein Increased
12 (.24%)
Haemoglobin Decreased
12 (.24%)
Hepatic Failure
12 (.24%)
Hypercapnia
12 (.24%)
Leukopenia
12 (.24%)
Renal Failure Chronic
12 (.24%)
Respiratory Failure
12 (.24%)
Sudden Death
12 (.24%)
Dermatitis Bullous
11 (.22%)
Dermatitis Exfoliative
11 (.22%)
Dialysis
11 (.22%)
Dizziness
11 (.22%)
Electrocardiogram Qt Prolonged
11 (.22%)
Headache
11 (.22%)
Oedema
11 (.22%)
Sepsis
11 (.22%)
Skin Necrosis
11 (.22%)
Aphasia
10 (.2%)

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This graph shows the top adverse events submitted to the FDA for Lasilix, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Lasilix is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Lasilix

What are the most common Lasilix adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Lasilix, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Lasilix is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Lasilix According to Those Reporting Adverse Events

Why are people taking Lasilix, according to those reporting adverse events to the FDA?

Drug Use For Unknown Indication
378
Hypertension
160
Cardiac Failure
83
Essential Hypertension
67
Ill-defined Disorder
29
Product Used For Unknown Indication
16
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Oedema
15
Oedema Peripheral
11
Renal Failure
9
Acute Pulmonary Oedema
9
Hypertensive Heart Disease
9
Renal Failure Chronic
7
Diuretic Therapy
5
Myocardial Infarction
4
Polyuria
4
Hypertensive Cardiomyopathy
4
Ischaemic Cardiomyopathy
4
Myocardial Ischaemia
3
Prophylaxis
3
Oedema Due To Cardiac Disease
3
Diuretic Effect
3
Unevaluable Event
3
Atrial Fibrillation
2
Cardiomegaly
2
Angina Pectoris
2
Oliguria
1
Mitral Valve Disease
1
Cardiac Disorder
1
Fluid Retention
1
Respiratory Failure
1
Cirrhosis Alcoholic
1
Ventricular Septal Defect
1
Pulmonary Oedema
1
Atrial Septal Defect
1
Cardiac Failure Congestive
1
Pulmonary Hypertension
1
Nephrotic Syndrome
1
Superinfection
1
Left Ventricular Failure
1
Cardiac Valve Disease
1
Premedication
1
Cardiomyopathy
1
Dyspnoea
1
Pregnancy Induced Hypertension
1
Wrong Drug Administered
1
Anaesthesia
1
Lymphoedema
1
Ascites
1
Congestive Cardiomyopathy
1

Lasilix Case Reports

What Lasilix safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Lasilix. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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