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DOLIPRANE

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Doliprane Adverse Events Reported to the FDA Over Time

How are Doliprane adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Doliprane, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Doliprane is flagged as the suspect drug causing the adverse event.

Most Common Doliprane Adverse Events Reported to the FDA

What are the most common Doliprane adverse events reported to the FDA?

Cytolytic Hepatitis
57 (3.13%)
Pyrexia
39 (2.14%)
Thrombocytopenia
33 (1.81%)
Condition Aggravated
26 (1.43%)
Neutropenia
25 (1.37%)
Pruritus
23 (1.26%)
Agranulocytosis
20 (1.1%)
Jaundice
20 (1.1%)
Vomiting
20 (1.1%)
Diarrhoea
19 (1.04%)
Rash Maculo-papular
18 (.99%)
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Colitis Ischaemic
15 (.82%)
Drug Ineffective
15 (.82%)
Eosinophilia
15 (.82%)
Renal Failure
15 (.82%)
Renal Failure Acute
15 (.82%)
Somnolence
15 (.82%)
Stevens-johnson Syndrome
15 (.82%)
Cholestasis
14 (.77%)
Asthenia
13 (.71%)
Headache
13 (.71%)
Nausea
13 (.71%)
Abdominal Pain
12 (.66%)
Epilepsy
11 (.6%)
Multi-organ Failure
11 (.6%)
Septic Shock
11 (.6%)
Alanine Aminotransferase Increased
10 (.55%)
Aspartate Aminotransferase Increase...
10 (.55%)
Convulsion
10 (.55%)
Gamma-glutamyltransferase Increased
10 (.55%)
General Physical Health Deteriorati...
10 (.55%)
Haemoglobin Decreased
10 (.55%)
Hepatitis
10 (.55%)
Inflammation
10 (.55%)
Pneumonia
10 (.55%)
Abdominal Pain Upper
9 (.49%)
Drug Interaction
9 (.49%)
Encephalopathy
9 (.49%)
Fatigue
9 (.49%)
Hepatic Failure
9 (.49%)
Hepatic Fibrosis
9 (.49%)
Hyperhidrosis
9 (.49%)
Hypotension
9 (.49%)
Leukopenia
9 (.49%)
Rectal Haemorrhage
9 (.49%)
Urticaria
9 (.49%)
Anaemia
8 (.44%)
Drug Exposure During Pregnancy
8 (.44%)
Drug Rash With Eosinophilia And Sys...
8 (.44%)
Erythema
8 (.44%)
Fall
8 (.44%)
Haemolytic Anaemia
8 (.44%)
International Normalised Ratio Incr...
8 (.44%)
Loss Of Consciousness
8 (.44%)
Lung Disorder
8 (.44%)
Respiratory Disorder
8 (.44%)
Toxic Skin Eruption
8 (.44%)
Acute Respiratory Distress Syndrome
7 (.38%)
Balance Disorder
7 (.38%)
Blood Alkaline Phosphatase Increase...
7 (.38%)
Blood Lactate Dehydrogenase Increas...
7 (.38%)
Chills
7 (.38%)
Cough
7 (.38%)
Face Oedema
7 (.38%)
Haematoma
7 (.38%)
Hepatitis Fulminant
7 (.38%)
Hypertension
7 (.38%)
Hyperthermia
7 (.38%)
Lymphadenopathy
7 (.38%)
Malaise
7 (.38%)
Medication Error
7 (.38%)
Monocytopenia
7 (.38%)
Oedema Peripheral
7 (.38%)
Paraesthesia
7 (.38%)
Suicide Attempt
7 (.38%)
Transaminases Increased
7 (.38%)
Arthralgia
6 (.33%)
Bacterial Infection
6 (.33%)
Blindness Transient
6 (.33%)
Blood Creatinine Increased
6 (.33%)
C-reactive Protein Increased
6 (.33%)
Cellulitis
6 (.33%)
Conjunctivitis
6 (.33%)
Creatinine Renal Clearance Decrease...
6 (.33%)
Dermatitis Bullous
6 (.33%)
Dermatitis Exfoliative
6 (.33%)
Feeding Disorder
6 (.33%)
Hepatic Enzyme Increased
6 (.33%)
Hepatitis Cholestatic
6 (.33%)
Hepatomegaly
6 (.33%)
Leukocytosis
6 (.33%)
Muscular Weakness
6 (.33%)
Pleural Effusion
6 (.33%)
Prurigo
6 (.33%)
Rash Erythematous
6 (.33%)
Skin Exfoliation
6 (.33%)
Tachycardia
6 (.33%)
Toxic Epidermal Necrolysis
6 (.33%)
Ventricular Hypoplasia
6 (.33%)
Altered State Of Consciousness
5 (.27%)
Anuria
5 (.27%)

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This graph shows the top adverse events submitted to the FDA for Doliprane, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Doliprane is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Doliprane

What are the most common Doliprane adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Doliprane, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Doliprane is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Doliprane According to Those Reporting Adverse Events

Why are people taking Doliprane, according to those reporting adverse events to the FDA?

Drug Use For Unknown Indication
210
Pain
125
Pyrexia
76
Product Used For Unknown Indication
28
Headache
27
Influenza
21
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Arthralgia
13
Bone Pain
12
Rheumatoid Arthritis
12
Bronchitis
12
Back Pain
11
Toothache
11
Crohns Disease
9
Nasopharyngitis
8
Prophylaxis
7
Ill-defined Disorder
7
Myalgia
6
Osteoarthritis
6
Hyperthermia
6
Chest Pain
6
Tonsillitis
6
Migraine
5
Bronchitis Acute
4
Gastroenteritis
4
Pharyngolaryngeal Pain
4
Unevaluable Event
4
Pharyngitis
4
Ankylosing Spondylitis
4
Musculoskeletal Pain
3
Suicide Attempt
3
Tracheobronchitis
3
Myositis
3
Pain In Extremity
3
Cancer Pain
3
Pyelonephritis Acute
3
Ear Infection
3
Neck Pain
3
Upper Respiratory Tract Infection
3
Abdominal Pain
3
Laryngitis
3
Chills
2
Cough
2
Otitis Media Acute
2
Analgesic Effect
2
Renal Colic
2
Infection
2
Shoulder Pain
2
Viral Tonsillitis
2
H1n1 Influenza
2
Lung Disorder
2
Joint Swelling
2

Doliprane Case Reports

What Doliprane safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Doliprane. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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