DrugCite
Search

DOCETAXEL

Adverse Events
Drug Profile
Learn More
Reference
About Results
Comments

Docetaxel Adverse Events Reported to the FDA Over Time

How are Docetaxel adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Docetaxel, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Docetaxel is flagged as the suspect drug causing the adverse event.

Most Common Docetaxel Adverse Events Reported to the FDA

What are the most common Docetaxel adverse events reported to the FDA?

Diarrhoea
1766 (2.47%)
Neutropenia
1567 (2.19%)
Febrile Neutropenia
1487 (2.08%)
Dyspnoea
1308 (1.83%)
Pyrexia
1267 (1.77%)
Nausea
1240 (1.73%)
Vomiting
1202 (1.68%)
Dehydration
1174 (1.64%)
Pneumonia
861 (1.2%)
Fatigue
756 (1.06%)
Asthenia
681 (.95%)
Show More Show More
Hypotension
677 (.95%)
Anaemia
667 (.93%)
Abdominal Pain
657 (.92%)
Interstitial Lung Disease
657 (.92%)
White Blood Cell Count Decreased
585 (.82%)
Death
575 (.8%)
Sepsis
573 (.8%)
Mucosal Inflammation
541 (.76%)
Haemoglobin Decreased
516 (.72%)
Leukopenia
492 (.69%)
Pleural Effusion
473 (.66%)
Hyponatraemia
460 (.64%)
Hypokalaemia
449 (.63%)
Respiratory Failure
443 (.62%)
General Physical Health Deteriorati...
410 (.57%)
Renal Failure Acute
410 (.57%)
Renal Failure
404 (.56%)
Pulmonary Embolism
401 (.56%)
Pain
385 (.54%)
Stomatitis
361 (.5%)
Thrombocytopenia
360 (.5%)
Decreased Appetite
349 (.49%)
Neutrophil Count Decreased
349 (.49%)
Disease Progression
341 (.48%)
Chest Pain
326 (.46%)
Rash
319 (.45%)
Oedema Peripheral
305 (.43%)
Dizziness
296 (.41%)
Atrial Fibrillation
278 (.39%)
Septic Shock
278 (.39%)
Erythema
274 (.38%)
Malaise
273 (.38%)
Platelet Count Decreased
264 (.37%)
Cough
263 (.37%)
Syncope
263 (.37%)
Palmar-plantar Erythrodysaesthesia ...
262 (.37%)
Blood Creatinine Increased
260 (.36%)
Dysphagia
259 (.36%)
Infection
259 (.36%)
Back Pain
253 (.35%)
Confusional State
247 (.35%)
Constipation
242 (.34%)
Urinary Tract Infection
241 (.34%)
Weight Decreased
236 (.33%)
Cardiac Arrest
235 (.33%)
Pancytopenia
234 (.33%)
Multi-organ Failure
233 (.33%)
Neutropenic Sepsis
232 (.32%)
Myalgia
229 (.32%)
Disseminated Intravascular Coagulat...
225 (.31%)
Hypoxia
225 (.31%)
Fall
223 (.31%)
Pneumonitis
218 (.3%)
Anorexia
215 (.3%)
Malignant Neoplasm Progression
206 (.29%)
Arthralgia
205 (.29%)
Chills
204 (.29%)
Haematocrit Decreased
196 (.27%)
Oedema
193 (.27%)
Tachycardia
191 (.27%)
Deep Vein Thrombosis
190 (.27%)
Flushing
189 (.26%)
Myocardial Infarction
185 (.26%)
Hypocalcaemia
183 (.26%)
Loss Of Consciousness
183 (.26%)
Hypersensitivity
182 (.25%)
Hyperglycaemia
181 (.25%)
Gastrointestinal Haemorrhage
180 (.25%)
Alopecia
177 (.25%)
Alanine Aminotransferase Increased
172 (.24%)
Aspartate Aminotransferase Increase...
172 (.24%)
Acute Respiratory Distress Syndrome
168 (.23%)
Neuropathy Peripheral
166 (.23%)
Cardiac Failure
157 (.22%)
Colitis
157 (.22%)
Blood Pressure Decreased
153 (.21%)
Drug Toxicity
153 (.21%)
Chest Discomfort
151 (.21%)
Hypomagnesaemia
151 (.21%)
Infusion Related Reaction
151 (.21%)
Haemoptysis
149 (.21%)
Pneumothorax
149 (.21%)
Headache
144 (.2%)
Hepatic Failure
144 (.2%)
Intestinal Perforation
144 (.2%)
Heart Rate Increased
140 (.2%)
Ascites
138 (.19%)
Blood Sodium Decreased
136 (.19%)
Cardiac Failure Congestive
136 (.19%)
Bone Marrow Failure
135 (.19%)

ExportShare/Embed GraphExport Export Data

This graph shows the top adverse events submitted to the FDA for Docetaxel, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Docetaxel is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Docetaxel

What are the most common Docetaxel adverse events reported to the FDA?

Show More Show More

ExportShare/Embed Graph Export Export Data

This graph shows the top categories of adverse events submitted to the FDA for Docetaxel, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Docetaxel is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Docetaxel According to Those Reporting Adverse Events

Why are people taking Docetaxel, according to those reporting adverse events to the FDA?

Breast Cancer
4769
Prostate Cancer
1621
Non-small Cell Lung Cancer
1571
Breast Cancer Metastatic
911
Head And Neck Cancer
368
Gastric Cancer
334
Show More Show More
Lung Neoplasm Malignant
319
Drug Use For Unknown Indication
308
Prostate Cancer Metastatic
306
Neoplasm Malignant
258
Oesophageal Carcinoma
239
Ovarian Cancer
228
Squamous Cell Carcinoma
223
Chemotherapy
214
Pancreatic Carcinoma
149
Non-small Cell Lung Cancer Metastat...
102
Product Used For Unknown Indication
98
Metastatic Gastric Cancer
96
Non-small Cell Lung Cancer Stage Iv
95
Lung Cancer Metastatic
85
Lung Adenocarcinoma
82
Metastases To Bone
82
Oesophageal Adenocarcinoma
59
Prostate Cancer Stage Iv
58
Sarcoma
53
Breast Cancer Recurrent
51
Pancreatic Carcinoma Metastatic
51
Hypopharyngeal Cancer
48
Laryngeal Cancer
48
Breast Cancer Female
47
Neoplasm
45
Gastrooesophageal Cancer
45
Adenocarcinoma
40
Uterine Cancer
38
Bladder Cancer
38
Nasopharyngeal Cancer
37
Adenocarcinoma Pancreas
37
Metastasis
35
Lung Squamous Cell Carcinoma Stage ...
34
Bronchial Carcinoma
34
Metastases To Lung
34
Prostate Cancer Recurrent
32
Metastatic Neoplasm
31
Lip And/or Oral Cavity Cancer
31
Oesophageal Cancer Metastatic
30
Breast Cancer Stage Iv
30
Breast Cancer Stage Ii
29
Non-small Cell Lung Cancer Recurren...
29
Tongue Neoplasm Malignant Stage Uns...
29
Lung Adenocarcinoma Stage Iv
28
Carcinoma
26

Drug Labels

LabelLabelerEffective
DocetaxelHospira, Inc.09-NOV-11
Taxoteresanofi-aventis U.S. LLC13-DEC-11
Taxoteresanofi-aventis U.S. LLC05-JAN-12
DocetaxelAccord Healthcare Inc.01-APR-12
DocetaxelSandoz Inc01-APR-12
DocetaxelAccord Healthcare Inc.01-APR-12
DocefrezSun Pharma Global FZE20-JUL-12
DocetaxelWinthrop U.S.01-JAN-13

Docetaxel Case Reports

What Docetaxel safety concerns are being reported by doctors and researchers in the medical literature?

Powered by Google

About Results

This report contains aggregated drug side effects and adverse events for Docetaxel. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

Comments

Share your experience with Docetaxel.