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Cycrin Adverse Events Reported to the FDA Over Time

How are Cycrin adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Cycrin, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Cycrin is flagged as the suspect drug causing the adverse event.

Most Common Cycrin Adverse Events Reported to the FDA

What are the most common Cycrin adverse events reported to the FDA?

Breast Cancer
1856 (21.14%)
Breast Cancer Female
1606 (18.29%)
Breast Cancer Metastatic
178 (2.03%)
Drug Ineffective
146 (1.66%)
Unintended Pregnancy
128 (1.46%)
Breast Cancer In Situ
101 (1.15%)
Breast Operation
100 (1.14%)
Ovarian Cancer
86 (.98%)
Oestrogen Receptor Assay Positive
85 (.97%)
Mastectomy
70 (.8%)
Pain
68 (.77%)
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Cerebrovascular Accident
60 (.68%)
Progesterone Receptor Assay Positiv...
59 (.67%)
Thrombosis
58 (.66%)
Anxiety
56 (.64%)
Pulmonary Embolism
51 (.58%)
Depression
50 (.57%)
Myocardial Infarction
50 (.57%)
Deep Vein Thrombosis
40 (.46%)
Arthralgia
39 (.44%)
Drug Exposure During Pregnancy
38 (.43%)
Incorrect Dose Administered
38 (.43%)
Vaginal Haemorrhage
38 (.43%)
Inappropriate Schedule Of Drug Admi...
37 (.42%)
Menorrhagia
37 (.42%)
Nausea
37 (.42%)
Injury
36 (.41%)
Insomnia
35 (.4%)
Metrorrhagia
35 (.4%)
Breast Cancer Stage Iii
31 (.35%)
Lymphoedema
31 (.35%)
Condition Aggravated
29 (.33%)
Hypertension
29 (.33%)
Dizziness
28 (.32%)
Headache
28 (.32%)
Pregnancy With Injectable Contracep...
26 (.3%)
Weight Increased
26 (.3%)
Weight Decreased
24 (.27%)
Breast Disorder
23 (.26%)
Scar
23 (.26%)
Chest Pain
22 (.25%)
Feeling Abnormal
21 (.24%)
Dyspnoea
20 (.23%)
Fatigue
20 (.23%)
Breast Cancer Stage Ii
19 (.22%)
Haemorrhage
19 (.22%)
Malignant Breast Lump Removal
19 (.22%)
Osteoporosis
19 (.22%)
Rash
19 (.22%)
Vomiting
19 (.22%)
Alopecia
18 (.2%)
Asthma
18 (.2%)
Dysmenorrhoea
18 (.2%)
Hot Flush
18 (.2%)
Injection Site Reaction
18 (.2%)
Systemic Lupus Erythematosus
18 (.2%)
Asthenia
17 (.19%)
Death
17 (.19%)
Tremor
17 (.19%)
Abdominal Distension
16 (.18%)
Confusional State
16 (.18%)
Emotional Distress
16 (.18%)
Endometrial Cancer
16 (.18%)
Hypersensitivity
16 (.18%)
Metastases To Lymph Nodes
16 (.18%)
Abortion Spontaneous
15 (.17%)
Fall
15 (.17%)
Hypotension
15 (.17%)
Mood Altered
15 (.17%)
Oedema Peripheral
15 (.17%)
Scleroderma
15 (.17%)
Breast Mass
14 (.16%)
Urticaria
14 (.16%)
Arthritis
13 (.15%)
Back Pain
13 (.15%)
Cholelithiasis
13 (.15%)
Drug Ineffective For Unapproved Ind...
13 (.15%)
Emotional Disorder
13 (.15%)
Injection Site Pain
13 (.15%)
Lymphadenectomy
13 (.15%)
Malaise
13 (.15%)
Metastases To Bone
13 (.15%)
Nervousness
13 (.15%)
Osteopenia
13 (.15%)
Somnolence
13 (.15%)
Abdominal Pain
12 (.14%)
Abnormal Behaviour
12 (.14%)
Blood Cholesterol Increased
12 (.14%)
Breast Lump Removal
12 (.14%)
Cerebral Infarction
12 (.14%)
Decreased Appetite
12 (.14%)
Dehydration
12 (.14%)
Injection Site Atrophy
12 (.14%)
Marital Problem
12 (.14%)
Pregnancy
12 (.14%)
Pruritus
12 (.14%)
Pyrexia
12 (.14%)
Surgery
12 (.14%)
Diabetes Mellitus
11 (.13%)
Hyperhidrosis
11 (.13%)
Hyperlipidaemia
11 (.13%)

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This graph shows the top adverse events submitted to the FDA for Cycrin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Cycrin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Cycrin

What are the most common Cycrin adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Cycrin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Cycrin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Cycrin According to Those Reporting Adverse Events

Why are people taking Cycrin, according to those reporting adverse events to the FDA?

Hormone Replacement Therapy
9053
Menopausal Symptoms
644
Menopause
448
Contraception
386
Drug Use For Unknown Indication
117
Breast Cancer
54
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Product Used For Unknown Indication
47
Hormone Therapy
36
Menorrhagia
33
Hot Flush
28
Off Label Use
25
Menstruation Irregular
25
Osteoporosis
21
Breast Cancer Metastatic
19
Prophylaxis
18
Breast Cancer Recurrent
14
Osteoporosis Prophylaxis
12
Endometriosis
12
Amenorrhoea
11
Ill-defined Disorder
11
Endometrial Hyperplasia
11
Anorexia
10
Oestrogen Replacement Therapy
10
Menstrual Discomfort
9
Cardiac Disorder
9
Uterine Cancer
9
Menstrual Disorder
8
Endometrial Cancer
7
Menstrual Cycle Management
7
Hysterectomy
7
Decreased Appetite
6
Polycystic Ovaries
6
Metastases To Bone
6
Uterine Haemorrhage
6
Vaginal Haemorrhage
5
Increased Appetite
5
Lymphangioleiomyomatosis
4
Breast Cancer Female
4
Hormone Level Abnormal
4
Mood Swings
4
Postmenopause
3
Dysmenorrhoea
3
Injectable Contraception
3
Pelvic Pain
3
Sexually Inappropriate Behaviour
3
Postmenopausal Haemorrhage
3
Night Sweats
3
Depression
2
Metastasis
2
Abortion Threatened
2
Metrorrhagia
2

Cycrin Case Reports

What Cycrin safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Cycrin. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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