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CORTICOSTEROIDS

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Corticosteroids Adverse Events Reported to the FDA Over Time

How are Corticosteroids adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Corticosteroids, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Corticosteroids is flagged as the suspect drug causing the adverse event.

Most Common Corticosteroids Adverse Events Reported to the FDA

What are the most common Corticosteroids adverse events reported to the FDA?

Osteonecrosis
66 (1.12%)
Pyrexia
58 (.99%)
Respiratory Failure
48 (.82%)
Pneumonia
47 (.8%)
Sepsis
45 (.76%)
Drug Ineffective
41 (.7%)
Diarrhoea
40 (.68%)
Condition Aggravated
37 (.63%)
Dyspnoea
37 (.63%)
Vomiting
36 (.61%)
Asthenia
35 (.59%)
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Fatigue
35 (.59%)
Nausea
35 (.59%)
Gastrointestinal Haemorrhage
34 (.58%)
Pain In Extremity
34 (.58%)
Drug Exposure During Pregnancy
33 (.56%)
Depression
32 (.54%)
Oedema Peripheral
32 (.54%)
Septic Shock
32 (.54%)
Graft Versus Host Disease
30 (.51%)
Myalgia
30 (.51%)
Multi-organ Failure
29 (.49%)
Renal Failure
29 (.49%)
Weight Decreased
29 (.49%)
Asthma
25 (.42%)
Convulsion
25 (.42%)
Insomnia
25 (.42%)
Cytomegalovirus Infection
24 (.41%)
Death
24 (.41%)
Multiple Sclerosis
24 (.41%)
Abdominal Pain
23 (.39%)
Anxiety
23 (.39%)
Lymphadenopathy
23 (.39%)
Pruritus
23 (.39%)
Anaemia
22 (.37%)
Back Pain
22 (.37%)
Candidiasis
22 (.37%)
Liver Function Test Abnormal
22 (.37%)
Pain
22 (.37%)
Weight Increased
22 (.37%)
Progressive Multifocal Leukoencepha...
21 (.36%)
Arthralgia
20 (.34%)
Blood Glucose Increased
20 (.34%)
Drug Dependence
19 (.32%)
Hypertension
19 (.32%)
Osteoarthritis
19 (.32%)
Tendon Disorder
19 (.32%)
Diabetes Mellitus
18 (.31%)
Infection
18 (.31%)
Dizziness
17 (.29%)
Drug Interaction
17 (.29%)
General Physical Health Deteriorati...
17 (.29%)
Headache
17 (.29%)
Hypotension
17 (.29%)
Musculoskeletal Pain
17 (.29%)
Palpitations
17 (.29%)
Premature Baby
17 (.29%)
Haemoglobin Decreased
16 (.27%)
Cardiac Arrest
15 (.25%)
Disease Recurrence
15 (.25%)
Gingivitis
15 (.25%)
Haemodynamic Instability
15 (.25%)
Hepatic Failure
15 (.25%)
Herpes Zoster
15 (.25%)
Injection Site Erythema
15 (.25%)
Kidney Transplant Rejection
15 (.25%)
Melaena
15 (.25%)
Neutropenia
15 (.25%)
Osteomyelitis
15 (.25%)
Pulmonary Embolism
15 (.25%)
Arthropathy
14 (.24%)
Blood Potassium Decreased
14 (.24%)
Bronchitis
14 (.24%)
Decreased Appetite
14 (.24%)
Dental Caries
14 (.24%)
Dyspnoea Exertional
14 (.24%)
Exostosis
14 (.24%)
Fall
14 (.24%)
Heart Rate Increased
14 (.24%)
Hyperglycaemia
14 (.24%)
Hypoglycaemia
14 (.24%)
Muscle Spasms
14 (.24%)
Pancytopenia
14 (.24%)
Sinusitis
14 (.24%)
Swelling
14 (.24%)
Thrombocytopenia
14 (.24%)
Urinary Tract Infection
14 (.24%)
Arterial Disorder
13 (.22%)
Blood Creatinine Increased
13 (.22%)
Blood Testosterone Decreased
13 (.22%)
Confusional State
13 (.22%)
Epidural Lipomatosis
13 (.22%)
Erythema
13 (.22%)
Hepatic Enzyme Increased
13 (.22%)
Multiple Sclerosis Relapse
13 (.22%)
Pharyngitis Streptococcal
13 (.22%)
Platelet Count Decreased
13 (.22%)
Pneumocystis Jiroveci Pneumonia
13 (.22%)
Post Procedural Complication
13 (.22%)
Rash
13 (.22%)
Sensitivity Of Teeth
13 (.22%)

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This graph shows the top adverse events submitted to the FDA for Corticosteroids, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Corticosteroids is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Corticosteroids

What are the most common Corticosteroids adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Corticosteroids, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Corticosteroids is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Corticosteroids According to Those Reporting Adverse Events

Why are people taking Corticosteroids, according to those reporting adverse events to the FDA?

Idiopathic Thrombocytopenic Purpura
1037
Prophylaxis
548
Product Used For Unknown Indication
282
Drug Use For Unknown Indication
228
Premedication
167
Asthma
151
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Rheumatoid Arthritis
145
Renal Transplant
111
Crohns Disease
84
Psoriasis
70
Prophylaxis Against Transplant Reje...
61
Immunosuppression
54
Liver Transplant
51
Prophylaxis Against Graft Versus Ho...
37
Thrombocytopenia
37
Systemic Lupus Erythematosus
35
Graft Versus Host Disease
33
Multiple Sclerosis
32
Immunosuppressant Drug Therapy
26
Multiple Sclerosis Relapse
25
Colitis Ulcerative
25
Heart Transplant
23
Chronic Obstructive Pulmonary Disea...
23
Acute Graft Versus Host Disease
21
Prostate Cancer
18
Maternal Therapy To Enhance Foetal ...
18
Dermatitis Atopic
16
Multiple Myeloma
16
Wegeners Granulomatosis
16
Ill-defined Disorder
16
Lung Transplant
16
Juvenile Arthritis
16
Aplastic Anaemia
14
Eczema
13
Back Pain
12
Arthritis
12
Skin Disorder
11
Pain
10
Histiocytosis Haematophagic
10
Psoriatic Arthropathy
9
Drug Exposure During Pregnancy
9
Adrenal Insufficiency
9
Bronchitis
8
Polymyalgia Rheumatica
8
Hypersensitivity
8
Rash
7
Dyspnoea
7
Arthralgia
7
Exanthem
7
Autoimmune Hepatitis
7
Obstructive Airways Disorder
7

Corticosteroids Case Reports

What Corticosteroids safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Corticosteroids. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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