COMBIVIR

Combivir Adverse Events Reported to the FDA Over Time

How are Combivir adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Combivir, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Combivir is flagged as the suspect drug causing the adverse event.

Most Common Combivir Adverse Events Reported to the FDA

What are the most common Combivir adverse events reported to the FDA?

Drug Exposure During Pregnancy	1727 (9.68%)
Abortion Spontaneous	389 (2.18%)
Anaemia	319 (1.79%)
Premature Baby	292 (1.64%)
Stillbirth	249 (1.4%)
Pregnancy	212 (1.19%)
Pyrexia	179 (1%)
Abortion Induced	175 (.98%)
Vomiting	143 (.8%)
Diarrhoea	141 (.79%)
Nausea	127 (.71%)
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Cardiac Murmur	112 (.63%)
Abdominal Pain	106 (.59%)
Asthenia	106 (.59%)
Congenital Anomaly	106 (.59%)
Caesarean Section	104 (.58%)
Fatigue	100 (.56%)
Haemoglobin Decreased	99 (.56%)
Maternal Drugs Affecting Foetus	97 (.54%)
Alanine Aminotransferase Increased	94 (.53%)
Ventricular Septal Defect	94 (.53%)
Abdominal Distension	92 (.52%)
Pancytopenia	91 (.51%)
Exomphalos	90 (.5%)
Dyspnoea	88 (.49%)
Hepatitis	87 (.49%)
Neutropenia	87 (.49%)
Sepsis	87 (.49%)
Headache	84 (.47%)
Atrial Septal Defect	81 (.45%)
Cough	81 (.45%)
Intra-uterine Death	81 (.45%)
Ascites	80 (.45%)
Normal Newborn	80 (.45%)
Trisomy 21	77 (.43%)
Cardiac Malposition	74 (.41%)
Live Birth	71 (.4%)
Deformity Thorax	69 (.39%)
Diaphragmatic Aplasia	69 (.39%)
Aspartate Aminotransferase Increase...	67 (.38%)
Jaundice	67 (.38%)
Polydactyly	67 (.38%)
Premature Labour	67 (.38%)
Rash	66 (.37%)
Pallor	65 (.36%)
Pneumonia	65 (.36%)
Blood Bilirubin Increased	63 (.35%)
Cryptorchism	63 (.35%)
Malaise	63 (.35%)
Microcephaly	63 (.35%)
Patent Ductus Arteriosus	63 (.35%)
Hepatic Displacement	62 (.35%)
Talipes	61 (.34%)
Weight Decreased	61 (.34%)
Foetal Growth Retardation	60 (.34%)
Pre-eclampsia	58 (.33%)
Premature Rupture Of Membranes	58 (.33%)
Oedema Peripheral	56 (.31%)
Dizziness	54 (.3%)
Death	53 (.3%)
Pericardial Effusion	53 (.3%)
Pneumothorax	53 (.3%)
Thrombocytopenia	49 (.27%)
Confusional State	48 (.27%)
Respiratory Distress	48 (.27%)
Hydrops Foetalis	47 (.26%)
Hydronephrosis	46 (.26%)
Eating Disorder	45 (.25%)
Blood Alkaline Phosphatase Increase...	44 (.25%)
Blood Lactate Dehydrogenase Increas...	44 (.25%)
Gastroenteritis	44 (.25%)
Loss Of Consciousness	43 (.24%)
Pain In Extremity	43 (.24%)
Ultrasound Antenatal Screen Abnorma...	43 (.24%)
Cardiac Failure	41 (.23%)
Drug Interaction	41 (.23%)
Hepatotoxicity	41 (.23%)
Abdominal Hernia	40 (.22%)
Cardiomyopathy	40 (.22%)
Congenital Central Nervous System A...	40 (.22%)
Dehydration	40 (.22%)
Foetal Disorder	40 (.22%)
Cytolytic Hepatitis	39 (.22%)
Hepatic Enzyme Increased	39 (.22%)
Death Neonatal	38 (.21%)
Disseminated Intravascular Coagulat...	38 (.21%)
Developmental Delay	37 (.21%)
Leukopenia	37 (.21%)
Alpha 1 Foetoprotein Abnormal	36 (.2%)
Abdominal Pain Upper	35 (.2%)
Bone Marrow Failure	35 (.2%)
Heart Disease Congenital	35 (.2%)
Placental Disorder	35 (.2%)
Vanishing Bile Duct Syndrome	35 (.2%)
C-reactive Protein Increased	34 (.19%)
Chest Pain	34 (.19%)
Hepatomegaly	34 (.19%)
Laboratory Test Abnormal	34 (.19%)
Myocardial Infarction	34 (.19%)
Ultrasound Scan Abnormal	34 (.19%)
Spina Bifida	33 (.19%)

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This graph shows the top adverse events submitted to the FDA for Combivir, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Combivir is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Combivir

What are the most common Combivir adverse events reported to the FDA?

Chemical Injury And Poisoning	1863 (10.45%)
Abortions And Stillbirth	753 (4.22%)
Gastrointestinal Signs	605 (3.39%)
Hepatic And Hepatobiliary	551 (3.09%)
Anemias Nonhemolytic And Marrow Dep...	543 (3.04%)
Cardiac And Vascular Disorders Cong...	503 (2.82%)
Respiratory	452 (2.53%)
Hepatobiliary	406 (2.28%)
Infections - Pathogen Unspecified	396 (2.22%)
Musculoskeletal And Connective Tiss...	396 (2.22%)
Neonatal And Perinatal Conditions	390 (2.19%)
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Pregnancy, Labour, Delivery And Pos...	375 (2.1%)
Epidermal And Dermal Conditions	350 (1.96%)
Neurological	318 (1.78%)
Obstetric And Gynecological Therape...	288 (1.61%)
Neurological Disorders Congenital	264 (1.48%)
Hematology Investigations	259 (1.45%)
Fetal Complications	209 (1.17%)
Body Temperature Conditions	195 (1.09%)
Cardiac And Vascular Investigations	195 (1.09%)
Myocardial	185 (1.04%)
Gastrointestinal Tract Disorders Co...	182 (1.02%)
Placental, Amniotic And Cavity Diso...	176 (.99%)
Gastrointestinal Motility And Defec...	173 (.97%)
Renal Disorders	167 (.94%)
Congenital And Hereditary	165 (.93%)
White Blood Cell	157 (.88%)
Maternal Complications Of Labour An...	138 (.77%)
Physical Examination Topics	134 (.75%)
Maternal Complications Of Pregnancy	132 (.74%)
Chromosomal Abnormalities And Abnor...	128 (.72%)
Enzyme	125 (.7%)
Cardiac Arrhythmias	123 (.69%)
Viral Infectious	114 (.64%)
Muscle	112 (.63%)
Appetite And General Nutritional	111 (.62%)
Therapeutic And Nontherapeutic Effe...	111 (.62%)
Bacterial Infectious	110 (.62%)
Musculoskeletal And Connective Tiss...	109 (.61%)
Protein And Chemistry Analyses	108 (.61%)
Respiratory Disorders Congenital	108 (.61%)
Reproductive Tract And Breast Disor...	107 (.6%)
Fatal Outcomes	101 (.57%)
Musculoskeletal And Connective Tiss...	99 (.56%)
Electrolyte And Fluid Balance Condi...	98 (.55%)
Urinary Tract Signs	93 (.52%)
Glucose Metabolism Disorders	90 (.5%)
Fetal And Neonatal	89 (.5%)
Peritoneal And Retroperitoneal Cond...	89 (.5%)
Headaches	85 (.48%)
Heart Failures	82 (.46%)
Vascular	81 (.45%)
Coronary Artery	76 (.43%)
Investigations, Imaging And Histopa...	76 (.43%)
Pleural	76 (.43%)
Acid-base	71 (.4%)
Cardiac Disorder Signs	71 (.4%)
Renal And Urinary Tract Disorders C...	71 (.4%)
Protozoal Infectious	63 (.35%)
Microbiology And Serology	62 (.35%)
Platelet	59 (.33%)
Cardiac Valve	58 (.33%)
Abdominal Hernias And Other Abdomin...	55 (.31%)
Pericardial	55 (.31%)
Spleen, Lymphatic And Reticulendoth...	55 (.31%)
Anxiety Disorders	54 (.3%)
Deliria	53 (.3%)
Medication Errors	51 (.29%)
Skin And Subcutaneous Tissue	51 (.29%)
Fungal Infectious	50 (.28%)
Allergic Conditions	48 (.27%)
Decreased And Nonspecific Blood Pre...	48 (.27%)
Coagulopathies And Bleeding Diathes...	47 (.26%)
Seizures	47 (.26%)
Neonatal Respiratory	46 (.26%)
Eating Disorders	45 (.25%)
Joint	45 (.25%)
Water, Electrolyte And Mineral	44 (.25%)
Metabolism	43 (.24%)
Urolithiases	43 (.24%)
Vision	43 (.24%)
Bile Duct	42 (.24%)
Lower Respiratory Tract Disorders	42 (.24%)
Metabolic And Nutritional Disorders...	42 (.24%)
Metabolic, Nutritional And Blood Ga...	42 (.24%)
Sleep Disorders	42 (.24%)
Bone Disorders	39 (.22%)
Renal And Urinary Tract Investigati...	39 (.22%)
Gastrointestinal Inflammatory Condi...	38 (.21%)
Movement Disorders	38 (.21%)
Depressed Mood Disorders	37 (.21%)
Central Nervous System Vascular	36 (.2%)
Gallbladder	36 (.2%)
Gastrointestinal Conditions	36 (.2%)
Hepatobiliary Disorders Congenital	36 (.2%)
Mycobacterial Infectious	36 (.2%)
Skin Appendage Conditions	35 (.2%)
Endocrine Disorders Congenital	34 (.19%)
Mental Impairment	34 (.19%)
Neuromuscular	34 (.19%)
Increased Intracranial Pressure And...	33 (.19%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Combivir, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Combivir is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.