CIPRO

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Cipro Adverse Events Reported to the FDA Over Time

How are Cipro adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Cipro, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Cipro is flagged as the suspect drug causing the adverse event.

Most Common Cipro Adverse Events Reported to the FDA

What are the most common Cipro adverse events reported to the FDA?

Arthralgia	934 (1.68%)
Tendon Rupture	707 (1.27%)
Pain In Extremity	705 (1.26%)
Tendonitis	673 (1.21%)
Pyrexia	618 (1.11%)
Renal Failure Acute	584 (1.05%)
Diarrhoea	574 (1.03%)
Drug Interaction	570 (1.02%)
Nausea	553 (.99%)
Dizziness	493 (.88%)
Rash	482 (.86%)
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Pain	449 (.81%)
Headache	425 (.76%)
Paraesthesia	425 (.76%)
Vomiting	424 (.76%)
Pruritus	410 (.74%)
Myalgia	403 (.72%)
Asthenia	398 (.71%)
Insomnia	384 (.69%)
Confusional State	370 (.66%)
Tendon Disorder	348 (.62%)
Fatigue	345 (.62%)
Anxiety	343 (.62%)
Oedema Peripheral	337 (.6%)
Gait Disturbance	333 (.6%)
Hypoaesthesia	331 (.59%)
Dyspnoea	324 (.58%)
Tendon Pain	322 (.58%)
Muscular Weakness	295 (.53%)
Urinary Tract Infection	295 (.53%)
Rotator Cuff Syndrome	281 (.5%)
Drug Ineffective	278 (.5%)
Tremor	273 (.49%)
Depression	257 (.46%)
Erythema	250 (.45%)
Malaise	248 (.44%)
Toxic Epidermal Necrolysis	248 (.44%)
Renal Failure	240 (.43%)
Back Pain	237 (.43%)
Convulsion	237 (.43%)
Abdominal Pain	236 (.42%)
Muscle Spasms	221 (.4%)
Feeling Abnormal	219 (.39%)
Burning Sensation	217 (.39%)
Drug Hypersensitivity	216 (.39%)
Hypersensitivity	215 (.39%)
Dehydration	214 (.38%)
Joint Swelling	212 (.38%)
International Normalised Ratio Incr...	211 (.38%)
Sepsis	206 (.37%)
Thrombocytopenia	205 (.37%)
Condition Aggravated	204 (.37%)
Urticaria	204 (.37%)
Musculoskeletal Pain	200 (.36%)
Hypotension	189 (.34%)
Tinnitus	189 (.34%)
Stevens-johnson Syndrome	186 (.33%)
Alanine Aminotransferase Increased	185 (.33%)
Abdominal Pain Upper	183 (.33%)
Abasia	182 (.33%)
Palpitations	182 (.33%)
Vision Blurred	182 (.33%)
Weight Decreased	182 (.33%)
Chills	178 (.32%)
Neuropathy Peripheral	176 (.32%)
Rhabdomyolysis	175 (.31%)
Multi-organ Failure	173 (.31%)
Chest Pain	172 (.31%)
Blood Creatinine Increased	171 (.31%)
Rash Maculo-papular	171 (.31%)
Tachycardia	171 (.31%)
Hypoglycaemia	170 (.3%)
Loss Of Consciousness	170 (.3%)
Fall	162 (.29%)
Hallucination	156 (.28%)
Pneumonia	155 (.28%)
Aspartate Aminotransferase Increase...	154 (.28%)
Heart Rate Increased	148 (.27%)
Rash Erythematous	145 (.26%)
Electrocardiogram Qt Prolonged	144 (.26%)
Drug Rash With Eosinophilia And Sys...	143 (.26%)
Agitation	142 (.25%)
Somnolence	134 (.24%)
Respiratory Failure	133 (.24%)
Anaemia	130 (.23%)
Dysphagia	130 (.23%)
Clostridium Difficile Colitis	127 (.23%)
Jaundice	126 (.23%)
Neck Pain	126 (.23%)
Death	124 (.22%)
Arthropathy	123 (.22%)
General Physical Health Deteriorati...	123 (.22%)
Blister	120 (.22%)
Blood Alkaline Phosphatase Increase...	120 (.22%)
Hepatic Failure	115 (.21%)
Hypertension	115 (.21%)
Torsade De Pointes	115 (.21%)
Atrial Fibrillation	113 (.2%)
Panic Attack	113 (.2%)
Renal Impairment	111 (.2%)
Balance Disorder	110 (.2%)

Share/Embed Graph Export Data

This graph shows the top adverse events submitted to the FDA for Cipro, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Cipro is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Cipro

What are the most common Cipro adverse events reported to the FDA?

Epidermal And Dermal Conditions	3543 (6.35%)
Neurological	3114 (5.58%)
Gastrointestinal Signs	1989 (3.57%)
Joint	1911 (3.43%)
Infections - Pathogen Unspecified	1858 (3.33%)
Musculoskeletal And Connective Tiss...	1760 (3.16%)
Tendon, Ligament And Cartilage	1496 (2.68%)
Injuries	1495 (2.68%)
Muscle	1449 (2.6%)
Therapeutic And Nontherapeutic Effe...	1280 (2.3%)
Renal Disorders	1208 (2.17%)
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Respiratory	1149 (2.06%)
Hepatic And Hepatobiliary	1127 (2.02%)
Cardiac Arrhythmias	1002 (1.8%)
Hematology Investigations	890 (1.6%)
Bacterial Infectious	873 (1.57%)
Gastrointestinal Motility And Defec...	821 (1.47%)
Anxiety Disorders	766 (1.37%)
Hepatobiliary	730 (1.31%)
Cardiac And Vascular Investigations	666 (1.19%)
Body Temperature Conditions	657 (1.18%)
Sleep Disorders	599 (1.07%)
Allergic Conditions	576 (1.03%)
Movement Disorders	569 (1.02%)
Deliria	546 (.98%)
Urinary Tract Signs	496 (.89%)
Headaches	465 (.83%)
White Blood Cell	465 (.83%)
Vision	464 (.83%)
Electrolyte And Fluid Balance Condi...	457 (.82%)
Seizures	416 (.75%)
Disturbances In Thinking	351 (.63%)
Renal And Urinary Tract Investigati...	350 (.63%)
Lower Respiratory Tract Disorders	349 (.63%)
Anemias Nonhemolytic And Marrow Dep...	338 (.61%)
Lifestyle Issues	334 (.6%)
Peripheral Neuropathies	310 (.56%)
Administration Site Reactions	306 (.55%)
Physical Examination Topics	303 (.54%)
Depressed Mood Disorders	298 (.53%)
Mental Impairment	298 (.53%)
Bone And Joint Injuries	297 (.53%)
Medication Errors	291 (.52%)
Fungal Infectious	288 (.52%)
Decreased And Nonspecific Blood Pre...	287 (.51%)
Skin Appendage Conditions	277 (.5%)
Angiedema And Urticaria	276 (.49%)
Oral Soft Tissue Conditions	270 (.48%)
Inner Ear And Viiith Cranial Nerve	259 (.46%)
Cardiac Disorder Signs	258 (.46%)
Gastrointestinal Hemorrhages	249 (.45%)
Platelet	245 (.44%)
Appetite And General Nutritional	233 (.42%)
Enzyme	229 (.41%)
Glucose Metabolism Disorders	219 (.39%)
Eye	208 (.37%)
Gastrointestinal Inflammatory Condi...	205 (.37%)
Skin Vascular Abnormalities	205 (.37%)
Suicidal And Self-injurious Behavio...	189 (.34%)
Coagulopathies And Bleeding Diathes...	181 (.32%)
Central Nervous System Vascular	173 (.31%)
Vascular	165 (.3%)
Nephropathies	163 (.29%)
Chemical Injury And Poisoning	159 (.29%)
Viral Infectious	158 (.28%)
Hearing	151 (.27%)
Metabolic, Nutritional And Blood Ga...	150 (.27%)
Fatal Outcomes	148 (.27%)
Ocular Infections, Irritations And ...	146 (.26%)
Changes In Physical Activity	140 (.25%)
Heart Failures	140 (.25%)
Hematological And Lymphoid Tissue T...	139 (.25%)
Mood Disorders	135 (.24%)
Vascular Hemorrhagic	133 (.24%)
Bone Disorders	129 (.23%)
Procedural And Device Related Injur...	128 (.23%)
Protein And Chemistry Analyses	124 (.22%)
Toxicology And Therapeutic Drug Mon...	124 (.22%)
Tongue Conditions	123 (.22%)
Water, Electrolyte And Mineral	122 (.22%)
Psychiatric	119 (.21%)
Bronchial Disorders	118 (.21%)
Vascular Hypertensive	118 (.21%)
Personality Disorders	116 (.21%)
Upper Respiratory Tract Disorders	116 (.21%)
Gastrointestinal Conditions	112 (.2%)
Coronary Artery	111 (.2%)
Product Quality Issues	107 (.19%)
Synovial And Bursal	103 (.18%)
Embolism And Thrombosis	101 (.18%)
Neuromuscular	101 (.18%)
Salivary Gland Conditions	94 (.17%)
Vascular Inflammations	94 (.17%)
Acid-base	91 (.16%)
Hemolyses And Related Conditions	91 (.16%)
Exocrine Pancreas Conditions	90 (.16%)
Ocular Neuromuscular	87 (.16%)
Pleural	85 (.15%)
Encephalopathies	82 (.15%)
Schizophrenia And Other Psychotic	82 (.15%)
Arteriosclerosis, Stenosis, Vascula...	80 (.14%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Cipro, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Cipro is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Cipro According to Those Reporting Adverse Events

Why are people taking Cipro, according to those reporting adverse events to the FDA?

Urinary Tract Infection	2676
Drug Use For Unknown Indication	1680
Product Used For Unknown Indication	1214
Infection	748
Prophylaxis	572
Pneumonia	440
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Cystitis	405
Prostatitis	324
Crohns Disease	305
Antibiotic Prophylaxis	304
Infection Prophylaxis	301
Diverticulitis	277
Sinusitis	230
Bronchitis	179
Pyrexia	172
Antibiotic Therapy	171
Sepsis	157
Pyelonephritis	150
Lower Respiratory Tract Infection	140
Bacterial Infection	127
Kidney Infection	127
Cellulitis	122
Pseudomonas Infection	121
Diarrhoea	108
Upper Respiratory Tract Infection	101
Osteomyelitis	88
Respiratory Tract Infection	88
Epididymitis	88
Ear Infection	81
Prostate Infection	75
Ill-defined Disorder	73
Lung Infection	73
Gastroenteritis	69
Staphylococcal Infection	68
Febrile Neutropenia	57
Wound Infection	56
Localised Infection	53
Bacteraemia	50
Lung Disorder	50
Urosepsis	47
Abscess	46
Cough	44
Pyelonephritis Acute	42
Bronchopneumonia	39
Chest Discomfort	36
Mycobacterium Avium Complex Infecti...	36
Nasopharyngitis	35
Surgery	34
Gastrointestinal Infection	34
Oropharyngeal Pain	32
Cholecystitis	32

Drug Labels

Label	Labeler	Effective
Cipro	Physicians Total Care, Inc.	27-APR-09
Cipro Hc	Stat Rx USA	27-OCT-09
Cipro	Physicians Total Care, Inc.	13-DEC-10
Cipro	Schering Plough Corporation	25-FEB-11
Cipro	Schering Plough Corporation	25-FEB-11
Cipro	Schering Plough Corporation	25-FEB-11
Ciprohc	Alcon Laboratories, Inc.	12-AUG-11
Cipro	Bayer HealthCare Pharmaceuticals Inc.	15-NOV-11
Cipro	Bayer HealthCare Pharmaceuticals Inc.	28-JUN-12
Cipro	Bayer HealthCare Pharmaceuticals Inc.	08-AUG-12

Cipro Case Reports

What Cipro safety concerns are being reported by doctors and researchers in the medical literature?

About Results

This report contains aggregated drug side effects and adverse events for Cipro. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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