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CANCIDAS

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Cancidas Adverse Events Reported to the FDA Over Time

How are Cancidas adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Cancidas, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Cancidas is flagged as the suspect drug causing the adverse event.

Most Common Cancidas Adverse Events Reported to the FDA

What are the most common Cancidas adverse events reported to the FDA?

Drug Ineffective
384 (7.03%)
Death
174 (3.19%)
Multi-organ Failure
108 (1.98%)
Septic Shock
102 (1.87%)
Bronchopulmonary Aspergillosis
97 (1.78%)
Sepsis
84 (1.54%)
Aspergillosis
72 (1.32%)
Respiratory Failure
63 (1.15%)
Pyrexia
62 (1.14%)
Stevens-johnson Syndrome
59 (1.08%)
Graft Versus Host Disease
55 (1.01%)
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Renal Failure
55 (1.01%)
Systemic Candida
55 (1.01%)
Renal Failure Acute
53 (.97%)
Fungal Infection
51 (.93%)
Alanine Aminotransferase Increased
50 (.92%)
Hepatic Failure
48 (.88%)
Acute Respiratory Distress Syndrome
42 (.77%)
Aspartate Aminotransferase Increase...
41 (.75%)
Convulsion
40 (.73%)
Drug Resistance
40 (.73%)
Rash
40 (.73%)
Candidiasis
38 (.7%)
Cardio-respiratory Arrest
37 (.68%)
Drug Interaction
37 (.68%)
Pneumonia
37 (.68%)
Acute Myeloid Leukaemia
35 (.64%)
Blood Bilirubin Increased
34 (.62%)
Condition Aggravated
31 (.57%)
Gamma-glutamyltransferase Increased
31 (.57%)
Overdose
31 (.57%)
Acute Graft Versus Host Disease
29 (.53%)
Hypotension
29 (.53%)
Blood Alkaline Phosphatase Increase...
28 (.51%)
Cholestasis
28 (.51%)
Hepatitis
27 (.49%)
Platelet Count Decreased
25 (.46%)
Hepatic Enzyme Increased
24 (.44%)
Jaundice
24 (.44%)
Liver Function Test Abnormal
24 (.44%)
Neutropenia
24 (.44%)
Bacterial Infection
23 (.42%)
Hepatic Necrosis
23 (.42%)
Pleural Effusion
23 (.42%)
Respiratory Distress
23 (.42%)
Transaminases Increased
23 (.42%)
Adverse Event
22 (.4%)
Anuria
22 (.4%)
Pancytopenia
22 (.4%)
Treatment Failure
22 (.4%)
Coagulopathy
21 (.38%)
Cytolytic Hepatitis
21 (.38%)
Dyspnoea
21 (.38%)
Infection
21 (.38%)
Medication Error
21 (.38%)
Tachycardia
21 (.38%)
Haemorrhage
20 (.37%)
Hepatotoxicity
20 (.37%)
Organ Failure
20 (.37%)
Thrombocytopenia
20 (.37%)
Toxic Epidermal Necrolysis
20 (.37%)
Confusional State
19 (.35%)
Shock
19 (.35%)
Endocarditis
18 (.33%)
General Physical Health Deteriorati...
18 (.33%)
Hypokalaemia
18 (.33%)
Pancreatitis
18 (.33%)
Pulmonary Haemorrhage
18 (.33%)
Arrhythmia
17 (.31%)
Coma
17 (.31%)
Febrile Neutropenia
17 (.31%)
Cardiac Arrest
16 (.29%)
Cytomegalovirus Infection
16 (.29%)
Disease Progression
16 (.29%)
Cardiac Failure
15 (.27%)
Cerebellar Syndrome
15 (.27%)
Electrocardiogram Qt Prolonged
15 (.27%)
Pathogen Resistance
15 (.27%)
Zygomycosis
15 (.27%)
Bradycardia
14 (.26%)
Candida Sepsis
14 (.26%)
Dermatitis Exfoliative
14 (.26%)
Fungaemia
14 (.26%)
Haemoglobin Decreased
14 (.26%)
Hepatitis Cholestatic
14 (.26%)
Oedema
14 (.26%)
Oedema Peripheral
14 (.26%)
Renal Impairment
14 (.26%)
Renal Tubular Disorder
14 (.26%)
Rhabdomyolysis
14 (.26%)
Tremor
14 (.26%)
Myocarditis
13 (.24%)
Off Label Use
13 (.24%)
Blood Creatinine Increased
12 (.22%)
Bone Marrow Failure
12 (.22%)
Fungal Sepsis
12 (.22%)
Gastrointestinal Haemorrhage
12 (.22%)
Hyperbilirubinaemia
12 (.22%)
Liver Disorder
12 (.22%)
Staphylococcal Infection
12 (.22%)
Systemic Mycosis
12 (.22%)

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This graph shows the top adverse events submitted to the FDA for Cancidas, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Cancidas is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Cancidas

What are the most common Cancidas adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Cancidas, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Cancidas is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Cancidas According to Those Reporting Adverse Events

Why are people taking Cancidas, according to those reporting adverse events to the FDA?

Aspergillosis
188
Candidiasis
178
Fungal Infection
170
Bronchopulmonary Aspergillosis
121
Systemic Candida
93
Pyrexia
88
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Drug Use For Unknown Indication
52
Sepsis
41
Febrile Neutropenia
29
Product Used For Unknown Indication
29
Antifungal Prophylaxis
28
Oesophageal Candidiasis
26
Prophylaxis
25
Infection
23
Evidence Based Treatment
21
Fungaemia
19
Pneumonia
15
Infection Prophylaxis
14
Candida Sepsis
14
Systemic Mycosis
14
Antifungal Treatment
13
Endocarditis
13
Lung Infection
12
Fungal Sepsis
12
Septic Shock
11
Pneumonia Fungal
10
Oral Candidiasis
7
Neutropenia
7
Respiratory Tract Infection Fungal
7
Urinary Tract Infection Fungal
7
Respiratory Moniliasis
7
Endocarditis Candida
7
Fungal Endocarditis
6
Stem Cell Transplant
5
Acute Myeloid Leukaemia
5
Blood Culture Positive
5
Systemic Antifungal Treatment
4
Peritonitis
4
Zygomycosis
4
Lower Respiratory Tract Infection F...
4
Pelvic Abscess
4
Bacterial Infection
4
Torulopsis Infection
3
Systemic Inflammatory Response Synd...
3
Localised Infection
3
Septic Embolus
3
Abdominal Sepsis
3
Bronchopulmonary Aspergillosis Alle...
3
Device Related Infection
3
Abdominal Infection
3
Candida Pneumonia
3

Drug Labels

LabelLabelerEffective
CancidasMerck Sharp & Dohme Corp.08-JAN-13

Cancidas Case Reports

What Cancidas safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Cancidas. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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