BISOPROLOL

Bisoprolol Adverse Events Reported to the FDA Over Time

How are Bisoprolol adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Bisoprolol, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Bisoprolol is flagged as the suspect drug causing the adverse event.

Most Common Bisoprolol Adverse Events Reported to the FDA

What are the most common Bisoprolol adverse events reported to the FDA?

Bradycardia	339 (2.14%)
Drug Interaction	315 (1.98%)
Dizziness	281 (1.77%)
Hypotension	280 (1.76%)
Dyspnoea	249 (1.57%)
Renal Failure Acute	248 (1.56%)
Fall	236 (1.49%)
Atrial Fibrillation	219 (1.38%)
Fatigue	202 (1.27%)
Syncope	176 (1.11%)
Dehydration	167 (1.05%)
	Show More
Hyperkalaemia	149 (.94%)
Nausea	149 (.94%)
Diarrhoea	145 (.91%)
Malaise	142 (.89%)
Drug Ineffective	134 (.84%)
Oedema Peripheral	118 (.74%)
Asthenia	114 (.72%)
Ventricular Tachycardia	114 (.72%)
Paraesthesia	113 (.71%)
Vomiting	109 (.69%)
Loss Of Consciousness	106 (.67%)
Renal Failure	105 (.66%)
Feeling Abnormal	104 (.65%)
Confusional State	100 (.63%)
Blood Pressure Increased	96 (.6%)
Condition Aggravated	96 (.6%)
Cardiac Murmur	91 (.57%)
Cardiac Failure	90 (.57%)
Vertigo	83 (.52%)
Venous Pressure Jugular Increased	82 (.52%)
Left Ventricular Dysfunction	79 (.5%)
Dyspnoea Exertional	76 (.48%)
Hyponatraemia	76 (.48%)
General Physical Health Deteriorati...	75 (.47%)
Vision Blurred	75 (.47%)
Oedema	74 (.47%)
Suicide Attempt	74 (.47%)
Shock	73 (.46%)
Atrioventricular Block Complete	70 (.44%)
Hypokalaemia	70 (.44%)
Pruritus	69 (.43%)
Orthostatic Hypotension	66 (.42%)
International Normalised Ratio Incr...	65 (.41%)
Sinus Bradycardia	64 (.4%)
Hypoglycaemia	63 (.4%)
Blood Pressure Decreased	60 (.38%)
Dissociation	60 (.38%)
Hypoaesthesia	60 (.38%)
Visual Impairment	60 (.38%)
Somnolence	59 (.37%)
Hypertension	56 (.35%)
Coma	55 (.35%)
Blood Creatinine Increased	53 (.33%)
Rash	53 (.33%)
Intentional Overdose	51 (.32%)
Pyrexia	51 (.32%)
Palpitations	50 (.31%)
Weight Decreased	50 (.31%)
Anaemia	48 (.3%)
Agitation	47 (.3%)
Cerebrovascular Accident	47 (.3%)
Interstitial Lung Disease	47 (.3%)
Drug Hypersensitivity	46 (.29%)
Thrombocytopenia	46 (.29%)
Depression	45 (.28%)
Alanine Aminotransferase Increased	44 (.28%)
Chest Pain	44 (.28%)
Depressed Level Of Consciousness	44 (.28%)
Dialysis	44 (.28%)
Electrocardiogram Qrs Complex Prolo...	44 (.28%)
Headache	44 (.28%)
Haemoglobin Decreased	43 (.27%)
Overdose	43 (.27%)
Rhabdomyolysis	43 (.27%)
Aspartate Aminotransferase Increase...	42 (.26%)
Circulatory Collapse	42 (.26%)
Electrocardiogram Qt Prolonged	42 (.26%)
Left Ventricular Failure	42 (.26%)
Transaminases Increased	42 (.26%)
Cardio-respiratory Arrest	41 (.26%)
Cardiogenic Shock	41 (.26%)
Abdominal Pain	40 (.25%)
Multiple Drug Overdose Intentional	40 (.25%)
Angina Pectoris	39 (.25%)
Arrhythmia	39 (.25%)
Cardiac Arrest	39 (.25%)
Cytolytic Hepatitis	38 (.24%)
Drug Rash With Eosinophilia And Sys...	38 (.24%)
Presyncope	38 (.24%)
Tachycardia	38 (.24%)
Drug Exposure During Pregnancy	37 (.23%)
Gait Disturbance	37 (.23%)
Sepsis	37 (.23%)
Muscle Spasms	36 (.23%)
Myocardial Infarction	36 (.23%)
Gamma-glutamyltransferase Increased	35 (.22%)
Hallucination	33 (.21%)
Neutropenia	33 (.21%)
Bradyarrhythmia	32 (.2%)
Atrioventricular Block	31 (.2%)

Share/Embed Graph Export Data

This graph shows the top adverse events submitted to the FDA for Bisoprolol, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Bisoprolol is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Bisoprolol

What are the most common Bisoprolol adverse events reported to the FDA?

Cardiac Arrhythmias	1343 (8.46%)
Neurological	1095 (6.9%)
Cardiac And Vascular Investigations	646 (4.07%)
Epidermal And Dermal Conditions	627 (3.95%)
Respiratory	529 (3.33%)
Decreased And Nonspecific Blood Pre...	510 (3.21%)
Therapeutic And Nontherapeutic Effe...	510 (3.21%)
Electrolyte And Fluid Balance Condi...	504 (3.17%)
Renal Disorders	478 (3.01%)
Gastrointestinal Signs	427 (2.69%)
Injuries	342 (2.15%)
	Show More
Hepatic And Hepatobiliary	319 (2.01%)
Hematology Investigations	250 (1.57%)
Infections - Pathogen Unspecified	242 (1.52%)
Medication Errors	230 (1.45%)
Hepatobiliary	207 (1.3%)
Heart Failures	206 (1.3%)
Vision	193 (1.22%)
Lower Respiratory Tract Disorders	181 (1.14%)
Gastrointestinal Motility And Defec...	173 (1.09%)
Myocardial	158 (1%)
Central Nervous System Vascular	155 (.98%)
Deliria	155 (.98%)
Muscle	147 (.93%)
White Blood Cell	143 (.9%)
Coronary Artery	135 (.85%)
Suicidal And Self-injurious Behavio...	119 (.75%)
Renal And Urinary Tract Investigati...	116 (.73%)
Anemias Nonhemolytic And Marrow Dep...	112 (.71%)
Glucose Metabolism Disorders	112 (.71%)
Inner Ear And Viiith Cranial Nerve	101 (.64%)
Cardiac Disorder Signs	98 (.62%)
Chemical Injury And Poisoning	97 (.61%)
Physical Examination Topics	94 (.59%)
Body Temperature Conditions	90 (.57%)
Water, Electrolyte And Mineral	85 (.54%)
Joint	83 (.52%)
Anxiety Disorders	81 (.51%)
Urinary Tract Signs	78 (.49%)
Musculoskeletal And Connective Tiss...	77 (.48%)
Allergic Conditions	74 (.47%)
Appetite And General Nutritional	74 (.47%)
Platelet	74 (.47%)
Movement Disorders	73 (.46%)
Vascular Hypertensive	70 (.44%)
Enzyme	69 (.43%)
Metabolic, Nutritional And Blood Ga...	67 (.42%)
Hematological And Lymphoid Tissue T...	65 (.41%)
Bacterial Infectious	64 (.4%)
Depressed Mood Disorders	64 (.4%)
Headaches	62 (.39%)
Dissociative	60 (.38%)
Bone And Joint Injuries	59 (.37%)
Vascular	59 (.37%)
Acid-base	58 (.37%)
Disturbances In Thinking	56 (.35%)
Mental Impairment	56 (.35%)
Psychiatric	54 (.34%)
Arteriosclerosis, Stenosis, Vascula...	53 (.33%)
Bronchial Disorders	53 (.33%)
Cardiac Valve	51 (.32%)
Oral Soft Tissue Conditions	51 (.32%)
Pulmonary Vascular	47 (.3%)
Skin Appendage Conditions	46 (.29%)
Gastrointestinal Hemorrhages	44 (.28%)
Skin Vascular Abnormalities	44 (.28%)
Sleep Disorders	44 (.28%)
Angiedema And Urticaria	41 (.26%)
Bone, Calcium, Magnesium And Phosph...	39 (.25%)
Fungal Infectious	39 (.25%)
Lifestyle Issues	38 (.24%)
Neonatal And Perinatal Conditions	37 (.23%)
Fatal Outcomes	34 (.21%)
Seizures	34 (.21%)
Vascular Hemorrhagic	34 (.21%)
Protein And Chemistry Analyses	33 (.21%)
Personality Disorders	32 (.2%)
Obstetric And Gynecological Therape...	31 (.2%)
Nephropathies	30 (.19%)
Thyroid Gland	30 (.19%)
Fetal Complications	29 (.18%)
Toxicology And Therapeutic Drug Mon...	29 (.18%)
Viral Infectious	29 (.18%)
Hearing	28 (.18%)
Ocular Infections, Irritations And ...	27 (.17%)
Peritoneal And Retroperitoneal Cond...	27 (.17%)
Procedural And Device Related Injur...	27 (.17%)
Skin And Subcutaneous Tissue	26 (.16%)
Tongue Conditions	26 (.16%)
Exocrine Pancreas Conditions	25 (.16%)
Immunology And Allergy	25 (.16%)
Ocular Neuromuscular	25 (.16%)
Embolism And Thrombosis	24 (.15%)
Product Quality Issues	24 (.15%)
Upper Respiratory Tract Disorders	24 (.15%)
Eye	23 (.14%)
Gastrointestinal Ulceration And Per...	23 (.14%)
Neuromuscular	22 (.14%)
Pleural	22 (.14%)
Gallbladder	21 (.13%)
Peripheral Neuropathies	21 (.13%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Bisoprolol, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Bisoprolol is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.