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ANGIOMAX

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Angiomax Adverse Events Reported to the FDA Over Time

How are Angiomax adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Angiomax, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Angiomax is flagged as the suspect drug causing the adverse event.

Most Common Angiomax Adverse Events Reported to the FDA

What are the most common Angiomax adverse events reported to the FDA?

Coronary Artery Thrombosis
179 (3.54%)
Thrombosis In Device
169 (3.34%)
Thrombosis
157 (3.1%)
Haemorrhage
154 (3.04%)
Stent Occlusion
131 (2.59%)
Myocardial Infarction
130 (2.57%)
Hypotension
105 (2.07%)
Chest Pain
100 (1.98%)
Coagulation Time Abnormal
100 (1.98%)
Procedural Complication
89 (1.76%)
Cardiac Arrest
80 (1.58%)
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Coronary Artery Occlusion
76 (1.5%)
Cardio-respiratory Arrest
61 (1.21%)
International Normalised Ratio Incr...
59 (1.17%)
Cerebrovascular Accident
55 (1.09%)
Off Label Use
54 (1.07%)
Post Procedural Complication
51 (1.01%)
Haemorrhage Intracranial
50 (.99%)
Retroperitoneal Haemorrhage
50 (.99%)
Gastrointestinal Haemorrhage
48 (.95%)
Acute Myocardial Infarction
46 (.91%)
Haematoma
46 (.91%)
Coronary Artery Perforation
44 (.87%)
Coronary Artery Dissection
41 (.81%)
Ventricular Fibrillation
40 (.79%)
Vascular Pseudoaneurysm
38 (.75%)
Dyspnoea
37 (.73%)
Bradycardia
36 (.71%)
Haemoglobin Decreased
36 (.71%)
Cardiac Procedure Complication
35 (.69%)
Post Procedural Haemorrhage
35 (.69%)
Cardiogenic Shock
34 (.67%)
Drug Ineffective
33 (.65%)
Renal Failure
33 (.65%)
Coagulation Time Prolonged
32 (.63%)
Heparin-induced Thrombocytopenia
32 (.63%)
Activated Partial Thromboplastin Ti...
31 (.61%)
Overdose
29 (.57%)
Electrocardiogram St Segment Elevat...
28 (.55%)
Hypersensitivity
28 (.55%)
Cardiac Tamponade
27 (.53%)
Haematocrit Decreased
27 (.53%)
Platelet Count Decreased
27 (.53%)
Cerebral Haemorrhage
26 (.51%)
Ventricular Tachycardia
26 (.51%)
Coagulopathy
25 (.49%)
Anaphylactic Reaction
23 (.45%)
Death
23 (.45%)
Blood Pressure Increased
22 (.43%)
Coronary Artery Stenosis
22 (.43%)
Coronary Revascularisation
21 (.41%)
Iatrogenic Injury
21 (.41%)
Nausea
21 (.41%)
Blood Pressure Decreased
20 (.4%)
Puncture Site Haemorrhage
20 (.4%)
Thrombocytopenia
20 (.4%)
Haemodynamic Instability
18 (.36%)
Respiratory Failure
18 (.36%)
Unresponsive To Stimuli
18 (.36%)
Embolism
17 (.34%)
Headache
17 (.34%)
Vomiting
17 (.34%)
Catheter Thrombosis
16 (.32%)
Coagulation Time Shortened
16 (.32%)
Deep Vein Thrombosis
16 (.32%)
Haemothorax
16 (.32%)
Angina Unstable
15 (.3%)
Haemorrhagic Stroke
15 (.3%)
Operative Haemorrhage
15 (.3%)
Atrial Fibrillation
14 (.28%)
Drug Administration Error
14 (.28%)
Hypertension
14 (.28%)
Reperfusion Injury
14 (.28%)
Convulsion
13 (.26%)
Device Occlusion
13 (.26%)
Disseminated Intravascular Coagulat...
13 (.26%)
Medical Device Complication
13 (.26%)
Pneumonia
13 (.26%)
Prothrombin Time Prolonged
13 (.26%)
Underdose
13 (.26%)
Chest Discomfort
12 (.24%)
Ejection Fraction Decreased
12 (.24%)
Hepatic Failure
12 (.24%)
Pericardial Effusion
12 (.24%)
Post Procedural Haematoma
12 (.24%)
Agitation
11 (.22%)
Angina Pectoris
11 (.22%)
Arterial Thrombosis
11 (.22%)
Cardiac Disorder
11 (.22%)
Cardiac Failure Congestive
11 (.22%)
Loss Of Consciousness
11 (.22%)
Medication Error
11 (.22%)
Myocardial Ischaemia
11 (.22%)
Pleural Effusion
11 (.22%)
Pulmonary Haemorrhage
11 (.22%)
Pulmonary Oedema
11 (.22%)
Cardiac Death
10 (.2%)
Catheter Site Haemorrhage
10 (.2%)
Gingival Bleeding
10 (.2%)
Hyperhidrosis
10 (.2%)
Organ Failure
10 (.2%)

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This graph shows the top adverse events submitted to the FDA for Angiomax, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Angiomax is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Angiomax

What are the most common Angiomax adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Angiomax, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Angiomax is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Angiomax According to Those Reporting Adverse Events

Why are people taking Angiomax, according to those reporting adverse events to the FDA?

Percutaneous Coronary Intervention
691
Anticoagulant Therapy
101
Stent Placement
62
Coronary Angioplasty
45
Heparin-induced Thrombocytopenia
39
Acute Coronary Syndrome
32
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Acute Myocardial Infarction
31
Coronary Artery Bypass
27
Angioplasty
27
Drug Use For Unknown Indication
23
Catheterisation Cardiac
20
Product Used For Unknown Indication
19
Thrombosis Prophylaxis
13
Arteriogram Coronary
12
Coronary Arterial Stent Insertion
11
Peripheral Revascularisation
11
Antiplatelet Therapy
10
Carotid Artery Stent Insertion
10
Prophylaxis
7
Coronary Artery Surgery
6
Peripheral Vascular Disorder
6
Angina Pectoris
5
Mitral Valve Replacement
5
Myocardial Infarction
5
Cardiac Operation
4
Therapeutic Procedure
4
Angiogram
4
Cardiopulmonary Bypass
3
Surgery
3
Ill-defined Disorder
3
Angina Unstable
3
White Clot Syndrome
2
Heart Valve Replacement
2
Ultrasound Doppler
2
Ventricular Assist Device Insertion
2
Anticoagulation Drug Level
2
Extracorporeal Membrane Oxygenation
2
Off Label Use
2
Thrombosis
2
Arterectomy With Graft Replacement
2
Thrombolysis
2
Transplant
2
Aortic Valve Replacement
2
Laser Therapy
1
Angiogram Cerebral
1
Arterial Therapeutic Procedure
1
Aortic Surgery
1
Deep Vein Thrombosis
1
Aortic Bypass
1
Coagulopathy
1
Cardiac Pacemaker Insertion
1

Drug Labels

LabelLabelerEffective
AngiomaxThe Medicines Company01-JUN-10
AngiomaxCardinal Health11-OCT-11

Angiomax Case Reports

What Angiomax safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Angiomax. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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