ADVAFERON

Advaferon Adverse Events Reported to the FDA Over Time

How are Advaferon adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Advaferon, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Advaferon is flagged as the suspect drug causing the adverse event.

Most Common Advaferon Adverse Events Reported to the FDA

What are the most common Advaferon adverse events reported to the FDA?

Injection Site Necrosis	13 (3%)
Malaise	13 (3%)
Bacterial Infection	10 (2.31%)
Injection Site Ulcer	10 (2.31%)
Peritonsillitis	10 (2.31%)
White Blood Cell Count Decreased	9 (2.08%)
Anorexia	8 (1.85%)
Neutrophil Count Decreased	8 (1.85%)
Prostate Cancer	8 (1.85%)
Weight Decreased	8 (1.85%)
Alanine Aminotransferase Increased	7 (1.62%)
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Convulsion	7 (1.62%)
Platelet Count Decreased	7 (1.62%)
Pyrexia	7 (1.62%)
Skin Ulcer	7 (1.62%)
Interstitial Lung Disease	6 (1.39%)
Skin Necrosis	6 (1.39%)
Ascites	5 (1.15%)
Cerebral Haemorrhage	5 (1.15%)
Deafness	5 (1.15%)
Depression	5 (1.15%)
Erythema	5 (1.15%)
Pneumonia	5 (1.15%)
Rhabdomyolysis	5 (1.15%)
Anxiety	4 (.92%)
Aspartate Aminotransferase Increase...	4 (.92%)
Depressed Level Of Consciousness	4 (.92%)
Diabetes Mellitus	4 (.92%)
Electrocardiogram St Segment Depres...	4 (.92%)
Face Oedema	4 (.92%)
Insomnia	4 (.92%)
Intestinal Ischaemia	4 (.92%)
Oedema Peripheral	4 (.92%)
Staphylococcal Infection	4 (.92%)
Abdominal Distension	3 (.69%)
Affect Lability	3 (.69%)
Ammonia Increased	3 (.69%)
Autoimmune Disorder	3 (.69%)
Endocrine Ophthalmopathy	3 (.69%)
Enterococcal Infection	3 (.69%)
General Physical Health Deteriorati...	3 (.69%)
Generalised Oedema	3 (.69%)
Hepatic Neoplasm Malignant	3 (.69%)
Injection Site Induration	3 (.69%)
Mental Disorder	3 (.69%)
Nasopharyngitis	3 (.69%)
Pallor	3 (.69%)
Pancytopenia	3 (.69%)
Retinal Vein Occlusion	3 (.69%)
Vomiting	3 (.69%)
Weight Increased	3 (.69%)
Antinuclear Antibody Positive	2 (.46%)
Anuria	2 (.46%)
Arthralgia	2 (.46%)
Blood Lactate Dehydrogenase Increas...	2 (.46%)
Blood Pressure Decreased	2 (.46%)
Breast Cancer Male	2 (.46%)
Cellulitis	2 (.46%)
Completed Suicide	2 (.46%)
Diabetic Ketoacidosis	2 (.46%)
Dizziness	2 (.46%)
Eating Disorder	2 (.46%)
Emotional Disorder	2 (.46%)
Feeling Abnormal	2 (.46%)
Haemophilus Infection	2 (.46%)
Hemiplegia	2 (.46%)
Hyperamylasaemia	2 (.46%)
Hypertension	2 (.46%)
Hypothyroidism	2 (.46%)
Immunodeficiency	2 (.46%)
Injection Site Erythema	2 (.46%)
Injection Site Pruritus	2 (.46%)
Loss Of Consciousness	2 (.46%)
Meningitis	2 (.46%)
Mydriasis	2 (.46%)
Pain	2 (.46%)
Pain In Extremity	2 (.46%)
Pancreatitis Acute	2 (.46%)
Proteinuria	2 (.46%)
Pupillary Reflex Impaired	2 (.46%)
Rash	2 (.46%)
Rectal Cancer	2 (.46%)
Respiratory Failure	2 (.46%)
Retinal Haemorrhage	2 (.46%)
Sepsis	2 (.46%)
Skin Warm	2 (.46%)
Subcutaneous Haematoma	2 (.46%)
Systemic Sclerosis	2 (.46%)
Thalamus Haemorrhage	2 (.46%)
Thirst	2 (.46%)
Abdominal Pain Upper	1 (.23%)
Acute Prerenal Failure	1 (.23%)
Affective Disorder	1 (.23%)
Anaemia	1 (.23%)
Angina Pectoris	1 (.23%)
Anti-gad Antibody Positive	1 (.23%)
Anti-neutrophil Cytoplasmic Antibod...	1 (.23%)
Antibody Test Abnormal	1 (.23%)
Autoimmune Hepatitis	1 (.23%)
Autophony	1 (.23%)
Azotaemia	1 (.23%)

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This graph shows the top adverse events submitted to the FDA for Advaferon, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Advaferon is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Advaferon

What are the most common Advaferon adverse events reported to the FDA?

Administration Site Reactions	34 (7.85%)
Hematology Investigations	27 (6.24%)
Infections - Pathogen Unspecified	25 (5.77%)
Bacterial Infectious	22 (5.08%)
Epidermal And Dermal Conditions	17 (3.93%)
Hepatobiliary	14 (3.23%)
Physical Examination Topics	11 (2.54%)
Neurological	9 (2.08%)
Appetite And General Nutritional	8 (1.85%)
Central Nervous System Vascular	8 (1.85%)
Reproductive Neoplasms Male Maligna...	8 (1.85%)
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Body Temperature Conditions	7 (1.62%)
Cardiac And Vascular Investigations	7 (1.62%)
Gastrointestinal Signs	7 (1.62%)
Hearing	7 (1.62%)
Respiratory	7 (1.62%)
Seizures	7 (1.62%)
Skin And Subcutaneous Tissue	7 (1.62%)
Lower Respiratory Tract Disorders	6 (1.39%)
Mood Disorders	6 (1.39%)
Retina, Choroid And Vitreous Hemorr...	6 (1.39%)
Depressed Mood Disorders	5 (1.15%)
Glucose Metabolism Disorders	5 (1.15%)
Muscle	5 (1.15%)
Ocular Neuromuscular	5 (1.15%)
Peritoneal And Retroperitoneal Cond...	5 (1.15%)
Anemias Nonhemolytic And Marrow Dep...	4 (.92%)
Anxiety Disorders	4 (.92%)
Gastrointestinal Vascular Condition...	4 (.92%)
Immunology And Allergy	4 (.92%)
Metabolic, Nutritional And Blood Ga...	4 (.92%)
Microbiology And Serology	4 (.92%)
Musculoskeletal And Connective Tiss...	4 (.92%)
Renal Disorders	4 (.92%)
Sleep Disorders	4 (.92%)
Autoimmune	3 (.69%)
Connective Tissue Disorders	3 (.69%)
Gastrointestinal Neoplasms Malignan...	3 (.69%)
Hepatobiliary Neoplasms Malignant A...	3 (.69%)
Immunodeficiency Syndromes	3 (.69%)
Movement Disorders	3 (.69%)
Ocular Structural Change, Deposit A...	3 (.69%)
Psychiatric	3 (.69%)
Urinary Tract Signs	3 (.69%)
Vascular	3 (.69%)
Breast Neoplasms Malignant And Unsp...	2 (.46%)
Coronary Artery	2 (.46%)
Diabetic Complications	2 (.46%)
Eating Disorders	2 (.46%)
Enzyme	2 (.46%)
Exocrine Pancreas Conditions	2 (.46%)
Fungal Infectious	2 (.46%)
Hepatic And Hepatobiliary	2 (.46%)
Injuries	2 (.46%)
Joint	2 (.46%)
Metabolism	2 (.46%)
Suicidal And Self-injurious Behavio...	2 (.46%)
Thyroid Gland	2 (.46%)
Vascular Hypertensive	2 (.46%)
Acid-base	1 (.23%)
Bone And Joint Therapeutic Procedur...	1 (.23%)
Cardiac Arrhythmias	1 (.23%)
Cardiac Disorder Signs	1 (.23%)
Coagulopathies And Bleeding Diathes...	1 (.23%)
Diverticular	1 (.23%)
Encephalopathies	1 (.23%)
Eye	1 (.23%)
Gastrointestinal	1 (.23%)
Gastrointestinal Hemorrhages	1 (.23%)
Gastrointestinal Motility And Defec...	1 (.23%)
Headaches	1 (.23%)
Hematological And Lymphoid Tissue T...	1 (.23%)
Immune	1 (.23%)
Inner Ear And Viiith Cranial Nerve	1 (.23%)
Investigations, Imaging And Histopa...	1 (.23%)
Metastases	1 (.23%)
Ocular Infections, Irritations And ...	1 (.23%)
Pleural	1 (.23%)
Procedural And Device Related Injur...	1 (.23%)
Protein And Chemistry Analyses	1 (.23%)
Respiratory And Pulmonary Investiga...	1 (.23%)
Skin And Subcutaneous Tissue Therap...	1 (.23%)
Therapeutic And Nontherapeutic Effe...	1 (.23%)
Therapeutic Procedures And Supporti...	1 (.23%)
Tissue	1 (.23%)
Vision	1 (.23%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Advaferon, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Advaferon is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.