VITAMIN D

Vitamin D Adverse Events Reported to the FDA Over Time

How are Vitamin D adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Vitamin D, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Vitamin D is flagged as the suspect drug causing the adverse event.

Most Common Vitamin D Adverse Events Reported to the FDA

What are the most common Vitamin D adverse events reported to the FDA?

Nausea	137 (1.46%)
Drug Interaction	120 (1.28%)
Dizziness	114 (1.21%)
Ageusia	110 (1.17%)
Vomiting	101 (1.08%)
Diarrhoea	97 (1.03%)
Fatigue	91 (.97%)
Drug Ineffective	79 (.84%)
Headache	79 (.84%)
Pyrexia	79 (.84%)
Convulsion	68 (.72%)
	Show More
Insomnia	64 (.68%)
Asthenia	61 (.65%)
Fall	61 (.65%)
Dyspnoea	57 (.61%)
Rash	57 (.61%)
Pruritus	53 (.56%)
Confusional State	51 (.54%)
Constipation	48 (.51%)
Pain In Extremity	47 (.5%)
Pneumonia	46 (.49%)
Medication Error	45 (.48%)
Myocardial Infarction	44 (.47%)
Somnolence	44 (.47%)
Tremor	44 (.47%)
Decreased Appetite	42 (.45%)
Malaise	42 (.45%)
Blood Glucose Increased	41 (.44%)
Chest Pain	41 (.44%)
Feeling Abnormal	41 (.44%)
Hypotension	41 (.44%)
Pain	41 (.44%)
Weight Decreased	41 (.44%)
Abdominal Pain Upper	39 (.42%)
Arthralgia	39 (.42%)
Death	38 (.4%)
Dehydration	38 (.4%)
Drug Exposure During Pregnancy	38 (.4%)
International Normalised Ratio Incr...	38 (.4%)
Renal Failure Acute	38 (.4%)
Thrombocytopenia	38 (.4%)
Anaemia	37 (.39%)
Anosmia	37 (.39%)
Erythema	37 (.39%)
Toxic Epidermal Necrolysis	37 (.39%)
Anxiety	35 (.37%)
Abdominal Pain	34 (.36%)
Aspartate Aminotransferase Increase...	34 (.36%)
Depression	34 (.36%)
Cardiac Arrest	33 (.35%)
Condition Aggravated	33 (.35%)
Hypercalcaemia	33 (.35%)
Hypoaesthesia	33 (.35%)
Myalgia	33 (.35%)
Neutropenia	32 (.34%)
Urticaria	32 (.34%)
Alanine Aminotransferase Increased	31 (.33%)
Muscle Spasms	31 (.33%)
Stevens-johnson Syndrome	30 (.32%)
Disorientation	29 (.31%)
Haemoglobin Decreased	29 (.31%)
Wrong Drug Administered	28 (.3%)
Drug Rash With Eosinophilia And Sys...	27 (.29%)
Fibromyalgia	27 (.29%)
Lethargy	27 (.29%)
Oedema Peripheral	27 (.29%)
Tachycardia	27 (.29%)
Cerebrovascular Accident	26 (.28%)
Haemorrhage	26 (.28%)
Hypersensitivity	26 (.28%)
Memory Impairment	26 (.28%)
Overdose	26 (.28%)
Agitation	25 (.27%)
Pleural Effusion	25 (.27%)
Weight Increased	25 (.27%)
Blood Pressure Increased	24 (.26%)
Contusion	24 (.26%)
Dyspepsia	24 (.26%)
Flushing	24 (.26%)
Hypertension	24 (.26%)
Loss Of Consciousness	24 (.26%)
Maternal Drugs Affecting Foetus	24 (.26%)
Jaundice	23 (.24%)
Osteoporosis	23 (.24%)
Renal Failure	23 (.24%)
Blood Creatinine Increased	22 (.23%)
Blood Potassium Decreased	22 (.23%)
General Physical Health Deteriorati...	22 (.23%)
Completed Suicide	21 (.22%)
Haematocrit Decreased	21 (.22%)
Haematoma	21 (.22%)
Vision Blurred	21 (.22%)
Visual Impairment	21 (.22%)
Abortion Spontaneous	20 (.21%)
Cytolytic Hepatitis	20 (.21%)
Dysphagia	20 (.21%)
Liver Injury	20 (.21%)
Staphylococcal Infection	20 (.21%)
Sudden Death	20 (.21%)
Ascites	19 (.2%)
Balance Disorder	19 (.2%)

Share/Embed Graph Export Data

This graph shows the top adverse events submitted to the FDA for Vitamin D, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vitamin D is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Vitamin D

What are the most common Vitamin D adverse events reported to the FDA?

Neurological	594 (6.32%)
Epidermal And Dermal Conditions	460 (4.9%)
Gastrointestinal Signs	419 (4.46%)
Therapeutic And Nontherapeutic Effe...	272 (2.9%)
Hematology Investigations	216 (2.3%)
Respiratory	208 (2.21%)
Infections - Pathogen Unspecified	197 (2.1%)
Medication Errors	192 (2.04%)
Hepatic And Hepatobiliary	173 (1.84%)
Gastrointestinal Motility And Defec...	169 (1.8%)
Injuries	152 (1.62%)
	Show More
Cardiac Arrhythmias	134 (1.43%)
Muscle	128 (1.36%)
Hepatobiliary	124 (1.32%)
Musculoskeletal And Connective Tiss...	122 (1.3%)
Movement Disorders	115 (1.22%)
Renal Disorders	112 (1.19%)
Water, Electrolyte And Mineral	105 (1.12%)
Seizures	102 (1.09%)
Cardiac And Vascular Investigations	101 (1.08%)
Metabolic, Nutritional And Blood Ga...	99 (1.05%)
Appetite And General Nutritional	97 (1.03%)
Deliria	95 (1.01%)
Headaches	95 (1.01%)
Joint	94 (1%)
White Blood Cell	93 (.99%)
Sleep Disorders	91 (.97%)
Chemical Injury And Poisoning	90 (.96%)
Physical Examination Topics	90 (.96%)
Body Temperature Conditions	87 (.93%)
Anxiety Disorders	81 (.86%)
Renal And Urinary Tract Investigati...	74 (.79%)
Vision	73 (.78%)
Urinary Tract Signs	68 (.72%)
Allergic Conditions	67 (.71%)
Bacterial Infectious	67 (.71%)
Decreased And Nonspecific Blood Pre...	67 (.71%)
Central Nervous System Vascular	64 (.68%)
Electrolyte And Fluid Balance Condi...	63 (.67%)
Bone Disorders	61 (.65%)
Bone, Calcium, Magnesium And Phosph...	60 (.64%)
Coronary Artery	60 (.64%)
Anemias Nonhemolytic And Marrow Dep...	59 (.63%)
Fatal Outcomes	58 (.62%)
Mental Impairment	58 (.62%)
Vascular	57 (.61%)
Bone And Joint Injuries	56 (.6%)
Skin Appendage Conditions	55 (.59%)
Cardiac Disorder Signs	51 (.54%)
Vascular Hemorrhagic	50 (.53%)
Administration Site Reactions	49 (.52%)
Suicidal And Self-injurious Behavio...	48 (.51%)
Viral Infectious	46 (.49%)
Oral Soft Tissue Conditions	45 (.48%)
Cranial Nerve Disorders	44 (.47%)
Depressed Mood Disorders	44 (.47%)
Product Quality Issues	43 (.46%)
Lower Respiratory Tract Disorders	42 (.45%)
Mood Disorders	41 (.44%)
Disturbances In Thinking	40 (.43%)
Lipid Analyses	40 (.43%)
Angiedema And Urticaria	39 (.42%)
Platelet	39 (.42%)
Psychiatric	38 (.4%)
Bronchial Disorders	34 (.36%)
Enzyme	34 (.36%)
Lifestyle Issues	34 (.36%)
Toxicology And Therapeutic Drug Mon...	34 (.36%)
Pleural	33 (.35%)
Embolism And Thrombosis	32 (.34%)
Musculoskeletal And Connective Tiss...	31 (.33%)
Upper Respiratory Tract Disorders	30 (.32%)
Fungal Infectious	29 (.31%)
Procedural And Device Related Injur...	29 (.31%)
Gastrointestinal Hemorrhages	28 (.3%)
Musculoskeletal And Connective Tiss...	27 (.29%)
Reproductive Organ And Breast Inves...	27 (.29%)
Mycobacterial Infectious	26 (.28%)
Pulmonary Vascular	26 (.28%)
Skin Vascular Abnormalities	26 (.28%)
Spleen, Lymphatic And Reticulendoth...	25 (.27%)
Urolithiases	25 (.27%)
Vascular Hypertensive	25 (.27%)
Congenital And Hereditary	24 (.26%)
Eye	24 (.26%)
Gastrointestinal Tract Disorders Co...	24 (.26%)
Glucose Metabolism Disorders	24 (.26%)
Protein And Chemistry Analyses	24 (.26%)
Salivary Gland Conditions	24 (.26%)
Neonatal And Perinatal Conditions	23 (.24%)
Peripheral Neuropathies	23 (.24%)
Tissue	23 (.24%)
Vitamin Related	23 (.24%)
Abortions And Stillbirth	22 (.23%)
Obstetric And Gynecological Therape...	22 (.23%)
Peritoneal And Retroperitoneal Cond...	22 (.23%)
Cardiac Valve	21 (.22%)
Heart Failures	21 (.22%)
Arteriosclerosis, Stenosis, Vascula...	20 (.21%)
Endocrine Investigations	20 (.21%)
Nephropathies	19 (.2%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Vitamin D, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Vitamin D is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.