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CO TRIMOXAZOLE

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Co Trimoxazole Adverse Events Reported to the FDA Over Time

How are Co Trimoxazole adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Co Trimoxazole, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Co Trimoxazole is flagged as the suspect drug causing the adverse event.

Most Common Co Trimoxazole Adverse Events Reported to the FDA

What are the most common Co Trimoxazole adverse events reported to the FDA?

Pyrexia
41 (2.35%)
Renal Impairment
33 (1.89%)
Cholestasis
24 (1.37%)
Drug Toxicity
24 (1.37%)
Rash
24 (1.37%)
Hypertension
22 (1.26%)
Myopathy
22 (1.26%)
Renal Failure Acute
22 (1.26%)
Hyperlipidaemia
21 (1.2%)
Lymphadenopathy
21 (1.2%)
Neutropenia
21 (1.2%)
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Sepsis
21 (1.2%)
Vomiting
20 (1.15%)
Cachexia
19 (1.09%)
Drug Ineffective
19 (1.09%)
Graft Dysfunction
19 (1.09%)
Hepatic Encephalopathy
19 (1.09%)
Acute Hepatic Failure
18 (1.03%)
Cough
18 (1.03%)
Pharyngitis
18 (1.03%)
Disease Recurrence
17 (.97%)
Jaundice
17 (.97%)
Transplant Rejection
17 (.97%)
Vanishing Bile Duct Syndrome
17 (.97%)
Hepatic Function Abnormal
16 (.92%)
Hepatitis
16 (.92%)
Liver Function Test Abnormal
16 (.92%)
Alanine Aminotransferase Increased
15 (.86%)
Confusional State
15 (.86%)
Haemoglobin Decreased
15 (.86%)
Agitation
14 (.8%)
Anaemia
14 (.8%)
Nausea
14 (.8%)
Liver Transplant
13 (.74%)
Solitary Kidney
13 (.74%)
Blood Bilirubin Increased
12 (.69%)
Ocular Icterus
12 (.69%)
Pain In Extremity
12 (.69%)
Urine Colour Abnormal
12 (.69%)
Blood Alkaline Phosphatase Increase...
11 (.63%)
Blood Creatinine Increased
11 (.63%)
Blood Lactate Dehydrogenase Increas...
10 (.57%)
Drug Interaction
10 (.57%)
Leukopenia
10 (.57%)
Liver Disorder
10 (.57%)
Drug Eruption
9 (.52%)
Drug Exposure During Pregnancy
9 (.52%)
Hiv Infection
9 (.52%)
Hypersensitivity
9 (.52%)
Pancytopenia
9 (.52%)
Biopsy Liver Abnormal
8 (.46%)
Hepatomegaly
8 (.46%)
Pneumonia
8 (.46%)
Scleral Discolouration
8 (.46%)
Stevens-johnson Syndrome
8 (.46%)
Thrombocytopenia
8 (.46%)
Tuberculosis
8 (.46%)
Acute Myocardial Infarction
7 (.4%)
Dizziness
7 (.4%)
Drug Hypersensitivity
7 (.4%)
Foetal Growth Retardation
7 (.4%)
Hepatotoxicity
7 (.4%)
Pelvic Kidney
7 (.4%)
White Blood Cell Count Decreased
7 (.4%)
Blood Immunoglobulin E Increased
6 (.34%)
Erythema
6 (.34%)
Fatigue
6 (.34%)
Headache
6 (.34%)
Hepatic Necrosis
6 (.34%)
Hypotension
6 (.34%)
Multi-organ Failure
6 (.34%)
Pregnancy
6 (.34%)
Renal Failure
6 (.34%)
Respiratory Failure
6 (.34%)
Toxic Skin Eruption
6 (.34%)
Weight Decreased
6 (.34%)
Abdominal Pain
5 (.29%)
Condition Aggravated
5 (.29%)
Dehydration
5 (.29%)
Diarrhoea
5 (.29%)
Haemodialysis
5 (.29%)
Immune Reconstitution Syndrome
5 (.29%)
Inflammation
5 (.29%)
Maternal Drugs Affecting Foetus
5 (.29%)
Neutropenic Sepsis
5 (.29%)
Oral Candidiasis
5 (.29%)
Polyuria
5 (.29%)
Premature Baby
5 (.29%)
Toxic Epidermal Necrolysis
5 (.29%)
Acute Graft Versus Host Disease
4 (.23%)
Angioedema
4 (.23%)
Blood Glucose Increased
4 (.23%)
Cd4 Lymphocytes Decreased
4 (.23%)
Cholangitis
4 (.23%)
Congenital Anomaly
4 (.23%)
Dandy-walker Syndrome
4 (.23%)
Disseminated Intravascular Coagulat...
4 (.23%)
Drug Rash With Eosinophilia And Sys...
4 (.23%)
Face Oedema
4 (.23%)
General Physical Health Deteriorati...
4 (.23%)
Haematemesis
4 (.23%)

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This graph shows the top adverse events submitted to the FDA for Co Trimoxazole, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Co Trimoxazole is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Co Trimoxazole

What are the most common Co Trimoxazole adverse events reported to the FDA?

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This graph shows the top categories of adverse events submitted to the FDA for Co Trimoxazole, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Co Trimoxazole is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Co Trimoxazole According to Those Reporting Adverse Events

Why are people taking Co Trimoxazole, according to those reporting adverse events to the FDA?

Prophylaxis
125
Antifungal Prophylaxis
59
Infection Prophylaxis
53
Drug Use For Unknown Indication
51
Pneumocystis Jiroveci Pneumonia
31
Urinary Tract Infection
21
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Antibiotic Prophylaxis
15
Antiretroviral Therapy
13
Hiv Infection
8
Infection
7
Pneumocystis Jiroveci Infection
6
Pneumocystis Carinii Pneumonia
5
Upper Respiratory Tract Infection
5
Product Used For Unknown Indication
4
Whipples Disease
4
Hiv Test Positive
3
Acne
3
Cystic Fibrosis
2
Lung Infection
2
Pneumonia
2
Tuberculosis
2
Non-hodgkins Lymphoma
2
Cystitis
2
Toxoplasmosis Prophylaxis
2
Antibiotic Therapy
2
Diarrhoea
2
Sinusitis
2
Pyrexia
2
Influenza Like Illness
1
Stem Cell Transplant
1
Endocarditis Bacterial
1
Dysuria
1
Drug Exposure During Pregnancy
1
Burkholderia Cepacia Infection
1
Ear Infection
1
Acute Graft Versus Host Disease In ...
1
Stenotrophomonas Infection
1
Wound Infection Staphylococcal
1
Scrub Typhus
1
Respiratory Tract Infection
1
Opportunistic Infection
1
Multiple Myeloma
1
Salmonellosis
1
Uveitis
1
Pneumonia Legionella
1
Serratia Infection
1
Cellulitis
1
Bladder Disorder
1
Renal Transplant
1
Acquired Immunodeficiency Syndrome
1
Epididymitis
1

Co Trimoxazole Case Reports

What Co Trimoxazole safety concerns are being reported by doctors and researchers in the medical literature?

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About Results

This report contains aggregated drug side effects and adverse events for Co Trimoxazole. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

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