ALENDRONATE SODIUM

Alendronate Sodium Adverse Events Reported to the FDA Over Time

How are Alendronate Sodium adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Alendronate Sodium, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Alendronate Sodium is flagged as the suspect drug causing the adverse event.

Most Common Alendronate Sodium Adverse Events Reported to the FDA

What are the most common Alendronate Sodium adverse events reported to the FDA?

Femur Fracture	2153 (6.97%)
Low Turnover Osteopathy	903 (2.92%)
Stress Fracture	714 (2.31%)
Bone Disorder	707 (2.29%)
Fall	619 (2%)
Arthralgia	404 (1.31%)
Fracture	340 (1.1%)
Pain In Extremity	332 (1.07%)
Anxiety	300 (.97%)
Pain	266 (.86%)
Osteoarthritis	261 (.84%)
	Show More
Impaired Healing	250 (.81%)
Tooth Disorder	211 (.68%)
Hypertension	209 (.68%)
Back Pain	203 (.66%)
Gastrooesophageal Reflux Disease	203 (.66%)
Depression	177 (.57%)
Osteoporosis	172 (.56%)
Gait Disturbance	166 (.54%)
Hyperlipidaemia	164 (.53%)
Anaemia	154 (.5%)
Oedema Peripheral	147 (.48%)
Nausea	146 (.47%)
Osteonecrosis	145 (.47%)
Osteomyelitis	143 (.46%)
Foot Fracture	142 (.46%)
Myalgia	138 (.45%)
Fatigue	134 (.43%)
Device Failure	132 (.43%)
Vitamin D Deficiency	129 (.42%)
Multiple Fractures	126 (.41%)
Chest Pain	123 (.4%)
Arthropathy	122 (.39%)
Fracture Nonunion	121 (.39%)
Diarrhoea	117 (.38%)
Constipation	115 (.37%)
Pathological Fracture	115 (.37%)
Bone Density Decreased	112 (.36%)
Emotional Distress	110 (.36%)
Spinal Osteoarthritis	110 (.36%)
Adverse Drug Reaction	108 (.35%)
Headache	107 (.35%)
Insomnia	106 (.34%)
Intervertebral Disc Degeneration	103 (.33%)
Urinary Tract Infection	102 (.33%)
Dental Caries	100 (.32%)
Dyspnoea	99 (.32%)
Arthritis	97 (.31%)
Osteogenesis Imperfecta	97 (.31%)
Fear Of Disease	96 (.31%)
Intervertebral Disc Protrusion	96 (.31%)
Muscle Spasms	96 (.31%)
Asthenia	95 (.31%)
Drug Hypersensitivity	94 (.3%)
Chronic Obstructive Pulmonary Disea...	92 (.3%)
Bursitis	91 (.29%)
Cataract	88 (.28%)
Dizziness	86 (.28%)
Haemorrhagic Anaemia	83 (.27%)
Blood Cholesterol Increased	82 (.27%)
Cellulitis	82 (.27%)
Exostosis	82 (.27%)
Dysphagia	80 (.26%)
Haemorrhoids	80 (.26%)
Rash	80 (.26%)
Osteopenia	79 (.26%)
Jaw Disorder	78 (.25%)
Hypercholesterolaemia	77 (.25%)
Joint Swelling	77 (.25%)
Weight Decreased	77 (.25%)
Anhedonia	75 (.24%)
Quality Of Life Decreased	75 (.24%)
Asthma	74 (.24%)
Pyrexia	74 (.24%)
Anaemia Postoperative	72 (.23%)
Cough	71 (.23%)
Rotator Cuff Syndrome	71 (.23%)
Hip Fracture	70 (.23%)
Pneumonia	70 (.23%)
Tooth Extraction	70 (.23%)
Bone Pain	69 (.22%)
Bronchitis	67 (.22%)
Musculoskeletal Pain	67 (.22%)
Drug Ineffective	66 (.21%)
Pain In Jaw	66 (.21%)
Urinary Incontinence	66 (.21%)
Oral Infection	65 (.21%)
Vomiting	65 (.21%)
Abdominal Pain Upper	64 (.21%)
Muscular Weakness	64 (.21%)
Oesophagitis	64 (.21%)
Hypothyroidism	63 (.2%)
Rib Fracture	63 (.2%)
Adverse Event	62 (.2%)
Hypokalaemia	62 (.2%)
Oral Disorder	62 (.2%)
Sciatica	61 (.2%)
Paraesthesia	60 (.19%)
Ankle Fracture	59 (.19%)
Toothache	58 (.19%)
Contusion	57 (.18%)

Share/Embed Graph Export Data

This graph shows the top adverse events submitted to the FDA for Alendronate Sodium, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Alendronate Sodium is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Alendronate Sodium

What are the most common Alendronate Sodium adverse events reported to the FDA?

Bone And Joint Injuries	4271 (13.82%)
Bone Disorders	2511 (8.13%)
Joint	1444 (4.67%)
Infections - Pathogen Unspecified	1279 (4.14%)
Injuries	1130 (3.66%)
Musculoskeletal And Connective Tiss...	957 (3.1%)
Dental And Gingival Conditions	671 (2.17%)
Gastrointestinal Signs	616 (1.99%)
Anxiety Disorders	540 (1.75%)
Epidermal And Dermal Conditions	536 (1.73%)
Neurological	508 (1.64%)
	Show More
Gastrointestinal Motility And Defec...	501 (1.62%)
Musculoskeletal And Connective Tiss...	483 (1.56%)
Respiratory	469 (1.52%)
Muscle	391 (1.27%)
Procedural And Device Related Injur...	382 (1.24%)
Tissue	375 (1.21%)
Lipid Metabolism	310 (1%)
Therapeutic And Nontherapeutic Effe...	309 (1%)
Fractures	298 (.96%)
Depressed Mood Disorders	291 (.94%)
Oral Soft Tissue Conditions	289 (.94%)
Anemias Nonhemolytic And Marrow Dep...	282 (.91%)
Urinary Tract Signs	280 (.91%)
Bacterial Infectious	267 (.86%)
Vascular Hypertensive	243 (.79%)
Cardiac Arrhythmias	225 (.73%)
Bronchial Disorders	203 (.66%)
Upper Respiratory Tract Disorders	202 (.65%)
Renal Disorders	192 (.62%)
Electrolyte And Fluid Balance Condi...	183 (.59%)
Spinal Cord And Nerve Root	171 (.55%)
Gastrointestinal Inflammatory Condi...	163 (.53%)
Headaches	163 (.53%)
Allergic Conditions	162 (.52%)
Vitamin Related	161 (.52%)
Cardiac And Vascular Investigations	156 (.5%)
Synovial And Bursal	154 (.5%)
Gastrointestinal Hemorrhages	153 (.5%)
Gastrointestinal Ulceration And Per...	153 (.5%)
Sleep Disorders	150 (.49%)
Central Nervous System Vascular	146 (.47%)
Lower Respiratory Tract Disorders	141 (.46%)
Gastrointestinal Conditions	140 (.45%)
Hematology Investigations	139 (.45%)
Bone, Calcium, Magnesium And Phosph...	138 (.45%)
Physical Examination Topics	133 (.43%)
Skin Appendage Conditions	131 (.42%)
Anterior Eye Structural Change, Dep...	129 (.42%)
Peripheral Neuropathies	128 (.41%)
Mood Disorders	124 (.4%)
Coronary Artery	122 (.39%)
Musculoskeletal And Soft Tissue Inv...	121 (.39%)
Thyroid Gland	118 (.38%)
Glucose Metabolism Disorders	113 (.37%)
Lifestyle Issues	112 (.36%)
Arteriosclerosis, Stenosis, Vascula...	109 (.35%)
Musculoskeletal And Connective Tiss...	109 (.35%)
Uterine, Pelvic And Broad Ligament	107 (.35%)
Tendon, Ligament And Cartilage	103 (.33%)
Cardiac Disorder Signs	100 (.32%)
Medication Errors	98 (.32%)
Fungal Infectious	95 (.31%)
Vascular	94 (.3%)
Viral Infectious	93 (.3%)
Head And Neck Therapeutic Procedure...	92 (.3%)
Investigations, Imaging And Histopa...	90 (.29%)
Lipid Analyses	90 (.29%)
Vision	88 (.28%)
Gastrointestinal Vascular Condition...	83 (.27%)
Appetite And General Nutritional	77 (.25%)
Skin Vascular Abnormalities	77 (.25%)
Hepatic And Hepatobiliary	76 (.25%)
Embolism And Thrombosis	75 (.24%)
Body Temperature Conditions	74 (.24%)
Gallbladder	74 (.24%)
Product Quality Issues	72 (.23%)
Abdominal Hernias And Other Abdomin...	71 (.23%)
Cardiac Valve	66 (.21%)
Hepatobiliary	66 (.21%)
Bone And Joint Therapeutic Procedur...	64 (.21%)
Myocardial	64 (.21%)
White Blood Cell	64 (.21%)
Metabolic, Nutritional And Blood Ga...	63 (.2%)
Breast	62 (.2%)
Cutaneous Neoplasms Benign	59 (.19%)
Gastrointestinal Stenosis And Obstr...	59 (.19%)
Mental Impairment	59 (.19%)
Bladder And Bladder Neck Disorders	58 (.19%)
Inner Ear And Viiith Cranial Nerve	58 (.19%)
Aural	57 (.18%)
Hearing	54 (.17%)
Decreased And Nonspecific Blood Pre...	51 (.17%)
Respiratory And Mediastinal Neoplas...	51 (.17%)
Vascular Hemorrhagic	51 (.17%)
Endocrine Investigations	49 (.16%)
Movement Disorders	48 (.16%)
Diverticular	47 (.15%)
Ocular Infections, Irritations And ...	47 (.15%)
Ovarian And Fallopian Tube	47 (.15%)
Psychiatric	46 (.15%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Alendronate Sodium, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Alendronate Sodium is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.