Avinza and Drug Effect Decreased

This page shows results related to Avinza and Drug Effect Decreased from the FDA Adverse Event Reporting System (AERS).

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Avinza and Drug Effect Decreased

Age

50-59 Years	46
>60 Years	35
40-49 Years	21
30-39 Years	18
10-19 Years	1
20-29 Years	1

Gender

Male: 40%
Female: 50%
Gender Unknown: 10%

Outcome

What were the most common outcomes of those reporting Drug Effect Decreased?

Other	66
Hospitalization	61
Death	23
Required Intervention	9
Disability	2
Life Threatening	2

Reporter

Who most commonly reported Drug Effect Decreased?

Consumer	39
Physician	39
Pharmacist	30
Other	26

Therapy

Of those reporting Drug Effect Decreased, why were they taking Avinza?

Pain	45
Analgesia	18
Hospice Care	13
Cancer Pain	12
Back Pain	11

Other Medications

Which medications reported to the FDA are most commonly associated with Drug Effect Decreased?

Byetta	1712
Humira	1249
Enbrel	904
Tysabri	876
Duragesic-100	619
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Viagra	469
Lyrica	453
Fentanyl-100	390
Oxycontin	385
Remicade	353
Nexium	327
Pristiq	289
Strattera	282
Effexor Xr	270
Celebrex	267
Neurontin	263
Spiriva	241
Lunesta	231
Seroquel	202
Vyvanse	202
Lipitor	194
Fentanyl	188
Vioxx	181
Chantix	180
Proair Hfa	172
Fentanyl Transdermal System	162
Zoloft	159
Cymbalta	146
Bextra	143
Detrol La	142
Gabapentin	135
Levitra	123
Lioresal	118
Combivent	112
Xanax	105
Prilosec	105
Fentanyl Citrate	102
Effexor	101
Omeprazole	98
Mirapex	97
Symbicort	97
Advil Pm	95
Flomax	93
Morphine	88
Daytrana	85
Oxycodone Hcl	82
Duragesic	80
Symlin	79
Opana Er	76
Alprazolam	76
Toviaz	75

Is the adverse drug reaction you’re experiencing actually due to the drug you took?

The Naranjo Scale is a questionnaire for determining the likelihood of whether an adverse drug reaction is actually due to the drug or caused by other factors. Probability is assigned via a score termed definite, probable, possible or doubtful.^*

	YES	NO	UNKOWN
Are there previous conclusive reports on this reaction?
Did the adverse event appear after the suspected drug was administered?
Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered?
Did the adverse reaction reappear when the drug was readministered?
Are there alternative causes (other than the drug) that could on their own have caused the reaction?
Did the reaction reappear when a placebo was given?
Was the drug detected in the blood (or other fluids) in concentrations known to be toxic?
Was the reaction more severe when the dose was increased, or less severe when the dose was decreased?
Did the patient have a similar reaction to the same or similar drugs in any previous exposure?
Was the adverse event confirmed by any objective evidence?

Probability of an Adverse Event

Doubtful

Possible

Probable

Definite

^*Naranjo, et al. "A method for estimating the probability of adverse drug reactions." Clin Pharmacol Ther. 1981 Aug;30(2):239-45.

To learn more about all adverse events for Avinza, view the complete Avinza adverse event report.

Scientific Publications on Drug Effect Decreased

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