Augmentin and Eosinophilia

This page shows results related to Augmentin and Eosinophilia from the FDA Adverse Event Reporting System (AERS).

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Augmentin and Eosinophilia

Age

>60 Years	125
50-59 Years	25
30-39 Years	21
10-19 Years	9
40-49 Years	9
20-29 Years	8
0-12 Months	3
1-9 Years	2

Gender

Male: 56%
Female: 44%

Outcome

What were the most common outcomes of those reporting Eosinophilia?

Hospitalization	186
Other	31
Life Threatening	13
Death	12
Required Intervention	2

Reporter

Who most commonly reported Eosinophilia?

Consumer	119
Other	35
Physician	33
Pharmacist	4

Therapy

Of those reporting Eosinophilia, why were they taking Augmentin?

Bronchitis	18
Drug Use For Unknown Indication	15
Sinusitis	9
Urinary Tract Infection	9
Infection	8

Other Medications

Which medications reported to the FDA are most commonly associated with Eosinophilia?

Allopurinol	126
Clozaril	124
Lamictal	123
Tegretol	119
Augmentin 125	113
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Vancomycin	101
Omeprazole	98
Humira	97
Rifadin	91
Singulair	91
Clozapine	90
Carbamazepine	85
Gleevec	84
Zyprexa	83
Nexium	79
Rocephin	75
Cubicin	72
Lasix	68
Bactrim	64
Amoxicillin	64
Ketek	62
Plavix	61
Remicade	61
Acetaminophen	59
Fosamax	58
Ciprofloxacin	57
Lovenox	57
Zometa	56
Cordarone	55
Previscan	52
Aspirin	52
Xolair	50
Phenytoin	49
Isentress	49
Tazocilline	49
Enbrel	48
Vancomycin Hcl	47
Clarithromycin	47
Lipitor	46
Aranesp	46
Depakene	44
Lamisil	41
Claforan	40
Simvastatin	40
Ciflox	40
Ibuprofen	40
Augmentin	40
Clamoxyl	39
Tysabri	38
Tavanic	37
Truvada	37

Is the adverse drug reaction you’re experiencing actually due to the drug you took?

The Naranjo Scale is a questionnaire for determining the likelihood of whether an adverse drug reaction is actually due to the drug or caused by other factors. Probability is assigned via a score termed definite, probable, possible or doubtful.^*

	YES	NO	UNKOWN
Are there previous conclusive reports on this reaction?
Did the adverse event appear after the suspected drug was administered?
Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered?
Did the adverse reaction reappear when the drug was readministered?
Are there alternative causes (other than the drug) that could on their own have caused the reaction?
Did the reaction reappear when a placebo was given?
Was the drug detected in the blood (or other fluids) in concentrations known to be toxic?
Was the reaction more severe when the dose was increased, or less severe when the dose was decreased?
Did the patient have a similar reaction to the same or similar drugs in any previous exposure?
Was the adverse event confirmed by any objective evidence?

Probability of an Adverse Event

Doubtful

Possible

Probable

Definite

^*Naranjo, et al. "A method for estimating the probability of adverse drug reactions." Clin Pharmacol Ther. 1981 Aug;30(2):239-45.

To learn more about all adverse events for Augmentin, view the complete Augmentin adverse event report.

Scientific Publications on Eosinophilia

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