Akineton and Rhabdomyolysis

This page shows results related to Akineton and Rhabdomyolysis from the FDA Adverse Event Reporting System (AERS).

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Akineton and Rhabdomyolysis

Age

50-59 Years	14
>60 Years	6
10-19 Years	5
30-39 Years	4
40-49 Years	4

Gender

Male: 57%
Female: 43%

Outcome

What were the most common outcomes of those reporting Rhabdomyolysis?

Hospitalization	27
Other	19
Life Threatening	7
Disability	3
Death	1

Reporter

Who most commonly reported Rhabdomyolysis?

Physician	18
Other	13
Consumer	1

Therapy

Of those reporting Rhabdomyolysis, why were they taking Akineton?

Drug Use For Unknown Indication	7
Schizophrenia	6
Akathisia	5
Hypertension	3
Parkinsonism	2

Other Medications

Which medications reported to the FDA are most commonly associated with Rhabdomyolysis?

Zocor	2302
Simvastatin	1963
Lipitor	1396
Crestor	1293
Vytorin	555
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Zetia	382
Atorvastatin Calcium	352
Zyprexa	337
Risperdal	329
Propofol	293
Gemfibrozil	289
Cyclosporine	239
Lyrica	239
Seroquel	238
Clarithromycin	224
Fenofibrate	192
Aricept	174
Omeprazole	160
Fusidic Acid	152
Fluconazole	143
Cozaar	142
Lamisil	142
Pepcid	139
Atorvastatin	137
Diprivan	134
Risperidone	133
Mirtazapine	129
Acetaminophen	129
Metformin Hcl	124
Cymbalta	122
Ciprofloxacin	121
Diovan	118
Plavix	116
Vioxx	114
Cubicin	112
Sevoflurane	110
Abilify	110
Pravastatin	109
Ambisome	108
Furosemide	108
Haloperidol	107
Olanzapine	107
Lamotrigine	106
Voltaren	106
Lovastatin	106
Tahor	104
Tricor	104
Zometa	101
Aspirin	98
Clozaril	97
Gabapentin	97

Is the adverse drug reaction you’re experiencing actually due to the drug you took?

The Naranjo Scale is a questionnaire for determining the likelihood of whether an adverse drug reaction is actually due to the drug or caused by other factors. Probability is assigned via a score termed definite, probable, possible or doubtful.^*

	YES	NO	UNKOWN
Are there previous conclusive reports on this reaction?
Did the adverse event appear after the suspected drug was administered?
Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered?
Did the adverse reaction reappear when the drug was readministered?
Are there alternative causes (other than the drug) that could on their own have caused the reaction?
Did the reaction reappear when a placebo was given?
Was the drug detected in the blood (or other fluids) in concentrations known to be toxic?
Was the reaction more severe when the dose was increased, or less severe when the dose was decreased?
Did the patient have a similar reaction to the same or similar drugs in any previous exposure?
Was the adverse event confirmed by any objective evidence?

Probability of an Adverse Event

Doubtful

Possible

Probable

Definite

^*Naranjo, et al. "A method for estimating the probability of adverse drug reactions." Clin Pharmacol Ther. 1981 Aug;30(2):239-45.

To learn more about all adverse events for Akineton, view the complete Akineton adverse event report.

Scientific Publications on Rhabdomyolysis

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