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Aspirin and Alanine Aminotransferase Increased

This page shows results related to Aspirin and Alanine Aminotransferase Increased from the FDA Adverse Event Reporting System (AERS).

Click here to learn about all Aspirin adverse events.

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Aspirin and Alanine Aminotransferase Increased

Age

>60 Years
105
50-59 Years
43
40-49 Years
31
30-39 Years
29
20-29 Years
15
0-12 Months
9
10-19 Years
7
1-9 Years
5

Gender

Male: 47%
Female: 51%
Gender Unknown: 2%

Outcome

What were the most common outcomes of those reporting Alanine Aminotransferase Increased?

Hospitalization
200
Other
112
Death
108
Life Threatening
25
Disability
5
Required Intervention
2

Reporter

Who most commonly reported Alanine Aminotransferase Increased?

Physician
118
Other
76
Pharmacist
26
Consumer
15

Therapy

Of those reporting Alanine Aminotransferase Increased, why were they taking Aspirin?

Drug Use For Unknown Indication
37
Suicide Attempt
20
Angina Pectoris
10
Prophylaxis
8
Myocardial Infarction
8

Other Medications

Which medications reported to the FDA are most commonly associated with Alanine Aminotransferase Increased?

Tracleer
1572
Cymbalta
1118
Lipitor
724
Exjade
715
Arava
685
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Ketek
600
Acetaminophen
573
Zyprexa
535
Clozaril
484
Methotrexate
454
Tegretol
451
Lamisil
418
Lamictal
418
Simvastatin
400
Gleevec
386
Zometa
382
Enbrel
382
Remicade
367
Crestor
364
Cyclophosphamide
351
Strattera
346
Zocor
321
Accutane
321
Nexavar
320
Avonex
298
Voltaren
278
Lamivudine
276
Diovan
275
Humira
269
Cytarabine
268
Seroquel
257
Neoral
255
Peg-intron
246
Zetia
245
Velcade
240
Iressa
233
Rebif
231
Vioxx
230
Augmentin 125
230
Mylotarg
218
Aspirin
213
Ibuprofen
210
Tysabri
209
Carbamazepine
209
Prednisolone
205
Cyclosporine
205
Pegasys
203
Rebetol
203
Lapatinib
200
Ribavirin
195
Clozapine
185

Is the adverse drug reaction you’re experiencing actually due to the drug you took?

The Naranjo Scale is a questionnaire for determining the likelihood of whether an adverse drug reaction is actually due to the drug or caused by other factors. Probability is assigned via a score termed definite, probable, possible or doubtful.*

YESNOUNKOWN
Are there previous conclusive reports on this reaction?
Did the adverse event appear after the suspected drug was administered?
Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered?
Did the adverse reaction reappear when the drug was readministered?
Are there alternative causes (other than the drug) that could on their own have caused the reaction?
Did the reaction reappear when a placebo was given?
Was the drug detected in the blood (or other fluids) in concentrations known to be toxic?
Was the reaction more severe when the dose was increased, or less severe when the dose was decreased?
Did the patient have a similar reaction to the same or similar drugs in any previous exposure?
Was the adverse event confirmed by any objective evidence?
Probability of an Adverse Event
Doubtful
Possible
Probable
Definite

*Naranjo, et al. "A method for estimating the probability of adverse drug reactions." Clin Pharmacol Ther. 1981 Aug;30(2):239-45.

To learn more about all adverse events for Aspirin, view the complete Aspirin adverse event report.

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