Advil and Drug Dependence

This page shows results related to Advil and Drug Dependence from the FDA Adverse Event Reporting System (AERS).

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Advil and Drug Dependence

Age

50-59 Years	33
>60 Years	24
20-29 Years	16
40-49 Years	15
30-39 Years	9
10-19 Years	7

Gender

Male: 44%
Female: 52%
Gender Unknown: 4%

Outcome

What were the most common outcomes of those reporting Drug Dependence?

Other	166
Hospitalization	34
Death	11
Life Threatening	1
Required Intervention	1

Reporter

Who most commonly reported Drug Dependence?

Consumer	118
Other	19
Physician	17
Lawyer	2
Pharmacist	2

Therapy

Of those reporting Drug Dependence, why were they taking Advil?

Nasal Congestion	31
Insomnia	13
Drug Use For Unknown Indication	12
Sinus Disorder	9
Dyspnoea	8

Other Medications

Which medications reported to the FDA are most commonly associated with Drug Dependence?

Oxycontin	3871
Suboxone	494
Paxil	411
Lyrica	388
Xanax	356
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Effexor Xr	274
Oxycodone Hcl	271
Seroquel	239
Accutane	204
Fosamax	201
Percocet	194
Vioxx	179
Calcium Carbonate	167
Actiq	166
Duragesic-100	164
Neurontin	162
Zoloft	149
Alprazolam	147
Morphine Sulfate	146
Excedrin (migraine)	143
Effexor	140
Nicotine	132
Diazepam	123
Chantix	123
Vicodin	122
Paroxetine Hcl	118
Lorazepam	112
Otrivin	112
Nicorette	110
Valium	107
Ritalin	107
Zometa	104
Ambien	104
Ultram	103
Geodon	99
Tramadol Hcl	97
Cymbalta	96
Aleve (caplet)	95
Clonazepam	93
Methadone Hcl	87
Gabapentin	87
Lortab	85
Ms Contin	80
Zolpidem	76
Alcohol	73
Aredia	73
Cocaine	70
Excedrin Extra Strength Tablets	68
Pristiq	66
Dilaudid	65
Fentanyl	61

Is the adverse drug reaction you’re experiencing actually due to the drug you took?

The Naranjo Scale is a questionnaire for determining the likelihood of whether an adverse drug reaction is actually due to the drug or caused by other factors. Probability is assigned via a score termed definite, probable, possible or doubtful.^*

	YES	NO	UNKOWN
Are there previous conclusive reports on this reaction?
Did the adverse event appear after the suspected drug was administered?
Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered?
Did the adverse reaction reappear when the drug was readministered?
Are there alternative causes (other than the drug) that could on their own have caused the reaction?
Did the reaction reappear when a placebo was given?
Was the drug detected in the blood (or other fluids) in concentrations known to be toxic?
Was the reaction more severe when the dose was increased, or less severe when the dose was decreased?
Did the patient have a similar reaction to the same or similar drugs in any previous exposure?
Was the adverse event confirmed by any objective evidence?

Probability of an Adverse Event

Doubtful

Possible

Probable

Definite

^*Naranjo, et al. "A method for estimating the probability of adverse drug reactions." Clin Pharmacol Ther. 1981 Aug;30(2):239-45.

To learn more about all adverse events for Advil, view the complete Advil adverse event report.

Scientific Publications on Drug Dependence

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