DrugCite
Search

TOPLEXIL

Adverse Events
Drug Profile
Learn More
Reference
About Results
Comments

Toplexil Adverse Events Reported to the FDA Over Time

How are Toplexil adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Toplexil, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Toplexil is flagged as the suspect drug causing the adverse event.

Most Common Toplexil Adverse Events Reported to the FDA

What are the most common Toplexil adverse events reported to the FDA?

Stevens-johnson Syndrome
7 (3.18%)
Urticaria
7 (3.18%)
Eosinophilia
6 (2.73%)
Lymphadenopathy
6 (2.73%)
Pyrexia
6 (2.73%)
Rash Erythematous
6 (2.73%)
Conjunctivitis
4 (1.82%)
Diarrhoea
4 (1.82%)
Drug Rash With Eosinophilia And Sys...
4 (1.82%)
Fungal Infection
4 (1.82%)
Mouth Ulceration
4 (1.82%)
Show More Show More
Pharyngitis
4 (1.82%)
Swelling
4 (1.82%)
Thrombocytopenia
4 (1.82%)
Thrombocytopenic Purpura
4 (1.82%)
Abdominal Pain
3 (1.36%)
Erythema
3 (1.36%)
Fall
3 (1.36%)
Gastrointestinal Disorder
3 (1.36%)
Hepatitis Cholestatic
3 (1.36%)
Hypergammaglobulinaemia Benign Mono...
3 (1.36%)
Loss Of Consciousness
3 (1.36%)
Malaise
3 (1.36%)
Rash
3 (1.36%)
Rash Macular
3 (1.36%)
Renal Failure Acute
3 (1.36%)
Skin Exfoliation
3 (1.36%)
Tendon Rupture
3 (1.36%)
Agitation
2 (.91%)
Bronchitis
2 (.91%)
Caesarean Section
2 (.91%)
Condition Aggravated
2 (.91%)
Cytolytic Hepatitis
2 (.91%)
Drug Exposure During Pregnancy
2 (.91%)
Electrocardiogram Qt Prolonged
2 (.91%)
Foetal Arrhythmia
2 (.91%)
Generalised Oedema
2 (.91%)
Hallucination, Visual
2 (.91%)
Head Injury
2 (.91%)
Infection
2 (.91%)
Leukopenia
2 (.91%)
Lung Disorder
2 (.91%)
Nervousness
2 (.91%)
Pancreatitis Acute
2 (.91%)
Pleural Effusion
2 (.91%)
Pneumococcal Infection
2 (.91%)
Pneumonia Pneumococcal
2 (.91%)
Speech Disorder
2 (.91%)
Torsade De Pointes
2 (.91%)
Vomiting
2 (.91%)
Abdominal Pain Lower
1 (.45%)
Abnormal Behaviour
1 (.45%)
Acute Generalised Exanthematous Pus...
1 (.45%)
Agranulocytosis
1 (.45%)
Anaemia Macrocytic
1 (.45%)
Ascites
1 (.45%)
Ataxia
1 (.45%)
Autoimmune Thrombocytopenia
1 (.45%)
Blood Magnesium Decreased
1 (.45%)
Blood Pressure Increased
1 (.45%)
Bordetella Infection
1 (.45%)
Cholestasis
1 (.45%)
Clostridial Infection
1 (.45%)
Cough
1 (.45%)
Death
1 (.45%)
Decreased Appetite
1 (.45%)
Dermatitis Exfoliative
1 (.45%)
Disorientation
1 (.45%)
Dizziness
1 (.45%)
Drug Interaction
1 (.45%)
Dysphagia
1 (.45%)
Dystonia
1 (.45%)
Ecchymosis
1 (.45%)
Epstein-barr Virus Antibody Positiv...
1 (.45%)
Eyelid Oedema
1 (.45%)
Face Injury
1 (.45%)
Global Amnesia
1 (.45%)
Granulocytes Maturation Arrest
1 (.45%)
Histiocytosis Haematophagic
1 (.45%)
Hypersensitivity
1 (.45%)
Hypertension
1 (.45%)
Hypoglycaemia
1 (.45%)
Hypotension
1 (.45%)
Idiopathic Thrombocytopenic Purpura
1 (.45%)
Intestinal Villi Atrophy
1 (.45%)
Lactic Acidosis
1 (.45%)
Laryngeal Oedema
1 (.45%)
Lymphocytosis
1 (.45%)
Medication Error
1 (.45%)
Metrorrhagia
1 (.45%)
Migraine
1 (.45%)
Musculoskeletal Stiffness
1 (.45%)
Neutropenia
1 (.45%)
No Therapeutic Response
1 (.45%)
Oedema Peripheral
1 (.45%)
Oropharyngeal Pain
1 (.45%)
Overdose
1 (.45%)
Pancytopenia
1 (.45%)
Posture Abnormal
1 (.45%)
Pruritus
1 (.45%)
Purpura
1 (.45%)

ExportShare/Embed GraphExport Export Data

This graph shows the top adverse events submitted to the FDA for Toplexil, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Toplexil is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Toplexil

What are the most common Toplexil adverse events reported to the FDA?

Show More Show More

ExportShare/Embed Graph Export Export Data

This graph shows the top categories of adverse events submitted to the FDA for Toplexil, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Toplexil is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Common Uses of Toplexil According to Those Reporting Adverse Events

Why are people taking Toplexil, according to those reporting adverse events to the FDA?

Cough
20
Drug Use For Unknown Indication
16
Influenza
14
Bronchitis
14
Product Used For Unknown Indication
3
Nasopharyngitis
2
Show More Show More
Pharyngitis
2
Dyspnoea
2
Bronchial Obstruction
1
Headache
1
Productive Cough
1

Toplexil Case Reports

What Toplexil safety concerns are being reported by doctors and researchers in the medical literature?

Powered by Google

About Results

This report contains aggregated drug side effects and adverse events for Toplexil. The data has been pulled from the United States Food and Drug Administration's (US FDA) Adverse Event Reporting System (AERS), a database containing more than 4,000,000 adverse event reports.

DrugCite expands your query using the Unified Medical Language System (UMLS) to include generic drugs and primary active ingredients. While the core of DrugCite's advanced drug filtering algorithm is based on the industry standard UMLS, DrugCite's proprietary filtering system also includes dozens of additional steps to reconcile malformed drug names in the FDA's data.

DrugCite only counts a drug if the submitter of the adverse event indicates that the drug is suspected to have caused the adverse event.

Depending on how the data is aggregated, different counts may occur. When someone submits an adverse event to the FDA, the submitter can attribute multiple adverse events to one or more drugs. For example, an individual taking Paxil could submit the adverse events "anxiety" and "suicidal ideation" for the same individual safety report (ISR). This means when DrugCite aggregates by adverse event, two distinct adverse events are counted in the adverse event graph; once for "anxiety" and again for "suicidal ideation". However, when DrugCite aggregates by individual safety reports irrespective of the details of the adverse events contained within the safety report, the report is only counted once.

Comments

Share your experience with Toplexil.