PENICILLIN

Penicillin Adverse Events Reported to the FDA Over Time

How are Penicillin adverse event reports trending over time?

This graph shows volume of adverse events submitted to the FDA by quarter for Penicillin, as well as related generic and/or brandname drugs containing the same primary active ingredients. Adverse events are counted if Penicillin is flagged as the suspect drug causing the adverse event.

Most Common Penicillin Adverse Events Reported to the FDA

What are the most common Penicillin adverse events reported to the FDA?

Drug Hypersensitivity	846 (12.2%)
No Adverse Event	167 (2.41%)
Rash	164 (2.36%)
Hypersensitivity	129 (1.86%)
Pyrexia	111 (1.6%)
Urticaria	82 (1.18%)
Nausea	73 (1.05%)
Dyspnoea	68 (.98%)
Vomiting	63 (.91%)
Pruritus	54 (.78%)
Toxic Epidermal Necrolysis	54 (.78%)
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Headache	51 (.74%)
Convulsion	47 (.68%)
Diarrhoea	46 (.66%)
Stevens-johnson Syndrome	44 (.63%)
Injection Site Pain	43 (.62%)
Drug Ineffective	42 (.61%)
Malaise	42 (.61%)
Rash Maculo-papular	39 (.56%)
Anaphylactic Reaction	37 (.53%)
Erythema	37 (.53%)
Arthralgia	36 (.52%)
Fatigue	36 (.52%)
Alanine Aminotransferase Increased	35 (.5%)
Asthenia	35 (.5%)
Dizziness	35 (.5%)
Oedema Peripheral	32 (.46%)
Confusional State	31 (.45%)
Medication Error	29 (.42%)
Pain	29 (.42%)
Pain In Extremity	29 (.42%)
Swelling Face	29 (.42%)
Renal Failure Acute	27 (.39%)
Weight Decreased	27 (.39%)
Leukocytosis	26 (.37%)
Rash Erythematous	26 (.37%)
Heart Rate Increased	25 (.36%)
Feeling Abnormal	23 (.33%)
Muscular Weakness	23 (.33%)
Restlessness	23 (.33%)
Swelling	23 (.33%)
Abdominal Pain Upper	22 (.32%)
Aspartate Aminotransferase Increase...	22 (.32%)
Blood Alkaline Phosphatase Increase...	22 (.32%)
Death	22 (.32%)
Injection Site Erythema	22 (.32%)
Pharyngeal Oedema	22 (.32%)
Thrombocytopenia	22 (.32%)
Expired Drug Administered	21 (.3%)
Skin Exfoliation	21 (.3%)
Abdominal Pain	20 (.29%)
Decreased Appetite	20 (.29%)
Hypotension	20 (.29%)
Chromaturia	19 (.27%)
Drug Exposure During Pregnancy	19 (.27%)
Drug Rash With Eosinophilia And Sys...	19 (.27%)
Jaundice	19 (.27%)
Lymphadenopathy	19 (.27%)
Acute Generalised Exanthematous Pus...	18 (.26%)
Anxiety	18 (.26%)
Blood Creatinine Increased	18 (.26%)
Depression	18 (.26%)
Disturbance In Attention	18 (.26%)
Gamma-glutamyltransferase Increased	18 (.26%)
Tremor	18 (.26%)
Tunnel Vision	18 (.26%)
Blister	17 (.25%)
Chest Pain	17 (.25%)
Drug Interaction	17 (.25%)
Epistaxis	17 (.25%)
Hypoaesthesia	17 (.25%)
Myalgia	17 (.25%)
Oropharyngeal Pain	17 (.25%)
Pancytopenia	17 (.25%)
Sleep Disorder	17 (.25%)
Colitis	16 (.23%)
Dysphagia	16 (.23%)
Lymphopenia	16 (.23%)
Pallor	16 (.23%)
Renal Failure	16 (.23%)
Anaphylactic Shock	15 (.22%)
Candidiasis	15 (.22%)
Cough	15 (.22%)
Hyperchlorhydria	15 (.22%)
Infection	15 (.22%)
Injection Site Swelling	15 (.22%)
Musculoskeletal Discomfort	15 (.22%)
Oedema	15 (.22%)
Wrong Drug Administered	15 (.22%)
Blood Bilirubin Increased	14 (.2%)
Cardio-respiratory Arrest	14 (.2%)
Disorientation	14 (.2%)
Eosinophilia	14 (.2%)
Neutropenia	14 (.2%)
Rash Generalised	14 (.2%)
Sensory Disturbance	14 (.2%)
Septic Shock	14 (.2%)
Stress	14 (.2%)
Cardiac Arrest	13 (.19%)
Chills	13 (.19%)
Face Oedema	13 (.19%)

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This graph shows the top adverse events submitted to the FDA for Penicillin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Penicillin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.

Adverse Event Categories for Penicillin

What are the most common Penicillin adverse events reported to the FDA?

Allergic Conditions	1051 (15.15%)
Epidermal And Dermal Conditions	700 (10.09%)
Gastrointestinal Signs	257 (3.7%)
Infections - Pathogen Unspecified	198 (2.85%)
Neurological	192 (2.77%)
Respiratory	185 (2.67%)
Administration Site Reactions	172 (2.48%)
Medication Errors	158 (2.28%)
Bacterial Infectious	115 (1.66%)
Body Temperature Conditions	114 (1.64%)
Hepatic And Hepatobiliary	114 (1.64%)
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Hepatobiliary	110 (1.59%)
White Blood Cell	108 (1.56%)
Angiedema And Urticaria	93 (1.34%)
Muscle	89 (1.28%)
Hematology Investigations	79 (1.14%)
Cardiac And Vascular Investigations	77 (1.11%)
Musculoskeletal And Connective Tiss...	74 (1.07%)
Therapeutic And Nontherapeutic Effe...	74 (1.07%)
Urinary Tract Signs	63 (.91%)
Joint	62 (.89%)
Renal Disorders	60 (.86%)
Gastrointestinal Motility And Defec...	59 (.85%)
Headaches	56 (.81%)
Physical Examination Topics	55 (.79%)
Cardiac Arrhythmias	54 (.78%)
Seizures	53 (.76%)
Upper Respiratory Tract Disorders	51 (.74%)
Anxiety Disorders	48 (.69%)
Oral Soft Tissue Conditions	48 (.69%)
Deliria	46 (.66%)
Chemical Injury And Poisoning	43 (.62%)
Movement Disorders	41 (.59%)
Renal And Urinary Tract Investigati...	39 (.56%)
Viral Infectious	39 (.56%)
Sleep Disorders	38 (.55%)
Gastrointestinal Inflammatory Condi...	36 (.52%)
Vision	36 (.52%)
Enzyme	35 (.5%)
Mental Impairment	35 (.5%)
Decreased And Nonspecific Blood Pre...	33 (.48%)
Fungal Infectious	33 (.48%)
Skin Appendage Conditions	32 (.46%)
Platelet	31 (.45%)
Injuries	30 (.43%)
Metabolic, Nutritional And Blood Ga...	30 (.43%)
Ocular Infections, Irritations And ...	30 (.43%)
Anemias Nonhemolytic And Marrow Dep...	29 (.42%)
Appetite And General Nutritional	27 (.39%)
Coagulopathies And Bleeding Diathes...	27 (.39%)
Skin Vascular Abnormalities	26 (.37%)
Vascular	26 (.37%)
Changes In Physical Activity	25 (.36%)
Electrolyte And Fluid Balance Condi...	25 (.36%)
Embolism And Thrombosis	25 (.36%)
Fatal Outcomes	23 (.33%)
Central Nervous System Vascular	22 (.32%)
Gastrointestinal Conditions	22 (.32%)
Suicidal And Self-injurious Behavio...	22 (.32%)
Bronchial Disorders	20 (.29%)
Depressed Mood Disorders	20 (.29%)
Cardiac Disorder Signs	19 (.27%)
Lifestyle Issues	19 (.27%)
Spleen, Lymphatic And Reticulendoth...	19 (.27%)
Cardiac And Vascular Disorders Cong...	18 (.26%)
Gastrointestinal Hemorrhages	18 (.26%)
Neurological Disorders Of The Eye	18 (.26%)
Coronary Artery	17 (.25%)
Nephropathies	17 (.25%)
Arteriosclerosis, Stenosis, Vascula...	16 (.23%)
Disturbances In Thinking	16 (.23%)
Vascular Hemorrhagic	16 (.23%)
Eye	15 (.22%)
Immune	15 (.22%)
Immunology And Allergy	15 (.22%)
Microbiology And Serology	15 (.22%)
Skin And Subcutaneous Tissue	15 (.22%)
Tongue Conditions	15 (.22%)
Bone And Joint Injuries	14 (.2%)
Lower Respiratory Tract Disorders	14 (.2%)
Musculoskeletal And Connective Tiss...	13 (.19%)
Peripheral Neuropathies	13 (.19%)
Tissue	13 (.19%)
Vascular Inflammations	13 (.19%)
Dental And Gingival Conditions	12 (.17%)
Personality Disorders	12 (.17%)
Water, Electrolyte And Mineral	12 (.17%)
Gastrointestinal Ulceration And Per...	11 (.16%)
Obstetric And Gynecological Therape...	11 (.16%)
Food Intolerance Syndromes	10 (.14%)
Heart Failures	10 (.14%)
Inner Ear And Viiith Cranial Nerve	10 (.14%)
Protein And Chemistry Analyses	10 (.14%)
Psychiatric	10 (.14%)
Bile Duct	9 (.13%)
Mood Disorders	9 (.13%)
Schizophrenia And Other Psychotic	9 (.13%)
Acid-base	8 (.12%)
Gastrointestinal Vascular Condition...	8 (.12%)
Hemolyses And Related Conditions	8 (.12%)
Menstrual Cycle And Uterine Bleedin...	8 (.12%)

Share/Embed Graph Export Data

This graph shows the top categories of adverse events submitted to the FDA for Penicillin, as well as related generic and/or brandname drugs containing the same primary active ingredients, from Q1 2004 to Q3 2012. Adverse events are counted if Penicillin is flagged as a suspect drug causing the adverse event. For each adverse event listed, percent (%) represents percentage of the adverse event to all adverse events reported for the drug. Percent does not represent a rate related to drug utilization.